Core-007

核心007

• 批准号: 10409671
• 负责人: JAMES E. HEUBI
• 金额: $ 43.07万
• 依托单位: UNIVERSITY OF CINCINNATI
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-14 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10409671
• 关键词: Caring; Clinical; Clinical Research; Clinical Sciences; Health; Health system; Healthcare; Intervention; Knowledge; Laboratories; Lead; Learning; Organizational Models; System; Testing; Training; Translational Research; Work; clinical care; clinical center; design; improved outcome; informatics infrastructure

Creating a Learning Health System (LHS) that overcomes the artificial barriers between clinical care and research will require significant learning and change. We have developed extensive, world recognized expertise and capacity in health system transformation and have demonstrated that a network organizational model to create LHSs works at scale. Our objective is to develop and test interventions that facilitate the emergence of two pilot LHSs within our Academic Health Center (AHC). We will pursue two specific aims to: 1) engage stakeholders in co-designing and collaboratively testing interventions to facilitate emergence of LHSs that improve outcomes by integrating clinical/translational research with health care practice; and 2) develop a collaborative laboratory to further advance best practices for instantiating the networked organization by aligning and integrating functions across existing Center for Clinical and Translational Science and Training (CCTST) Cores. As a result of the proposed effort, we expect to have a replicable, tested approach to facilitating the emergence of LHSs within the AHC, as well as workforce, scientific, and informatics infrastructure to enable the CCTST to function as a learning system to pursue this work at the AHC and across the CTSA network. This is significant because it will further advance knowledge for how to accelerate the translation of research into improved outcomes and lead to better care and health for our region and the nation.

创建一个学习健康系统 (LHS)，克服临床护理和治疗之间的人为障碍 研究需要大量的学习和改变。我们开发了广泛的、世界认可的 卫生系统转型方面的专业知识和能力，并已证明网络组织 创建 LHS 的模型可以大规模发挥作用。我们的目标是开发和测试促进 我们的学术健康中心 (AHC) 内出现了两个试点 LHS。我们将追求两个具体目标：1) 让利益相关者参与共同设计和协作测试干预措施，以促进 LHS 的出现 通过将临床/转化研究与医疗保健实践相结合来改善结果； 2）开发一个 合作实验室进一步推进实例化网络组织的最佳实践 调整和整合现有临床和转化科学与培训中心的功能 (CCTST) 核心。作为拟议工作的结果，我们期望有一种可复制的、经过测试的方法来 促进 AHC 内 LHS 以及劳动力、科学和信息学的出现 使 CCTST 能够作为学习系统发挥作用的基础设施，以便在 AHC 和整个机构开展这项工作 CTSA 网络。这很重要，因为它将进一步推进有关如何加速的知识 将研究转化为改善的结果，并为我们地区和整个地区带来更好的护理和健康 国家。