Exploring Health Beliefs for Community Engagement and Diversity in Clinical Trials

探索临床试验中社区参与和多样性的健康信念

• 批准号: 10399907
• 负责人: Kimberly Page
• 金额: $ 22.08万
• 依托单位: UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2023-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10399907
• 关键词: Address; Area; Belief; Clinical Research; Clinical Trials; Clinical Trials Network; Communication; Communities; Community Health; Community Health Aides; Decision Making; Development; Dissemination and Implementation; Enrollment; Evaluation; Evidence based practice; Family; Feedback; Funding; Goals; Health; Health Personnel; Health Promotion; Health behavior; Healthcare; Individual; Institution; Interview; Knowledge; Literature; Locales; Location; Logic; Medical; Medical Research; Methods; Minority Groups; Modeling; National Institute of Drug Abuse; New Mexico; Online Systems; Outcome; Pathway interactions; Patients; Phase; Population; Population Heterogeneity; Practice based research; Predisposition; Process; Professional counselor; Provider; Research; Research Methodology; Research Personnel; Resources; Special Population; Structure; Support Groups; Surveys; Techniques; Testing; Training; Translational Research; Translations; Visual; Work; behavioral health; care providers; clinical trial participant; community engagement; field study; health belief; health disparity; health inequalities; health literacy; improved; interest; literacy; minority communities; motivational enhancement therapy; novel; opioid use disorder; peer; recruit; social factors; social health determinants; social vulnerability; substance use; tool

ABSTRACT Improving inclusion and engagement of diverse populations in clinical research can broaden the relevance and translation of research findings into practice. Many communities are under-represented in health research due to: lack of knowledge about clinical research, mistrust, lack of access, geo-location, and social factors. Lack of knowledge about how research works and how it can benefit communities is a common reason for non- engagement, especially if research is carried out in academic medical institutions and locations where a significant proportion of people do not access care. Providers and community health groups often lack knowledge and training about clinical research and how it may or may not align with patients’ and community priorities. To our knowledge, there is no compendium of tools aimed at advancing inclusion and engagement of diverse and minority populations in clinical research. In this supplemental application, we propose to develop such a toolkit. The goal of the toolkit will be to provide researchers and community partners a guide to taking the individual, cultural, and structural perspectives into consideration when proposing clinical research. We are specifically interested in advancing engagement in research and trials that deal with substance use, and especially opioid use disorder (OUD), in association with our HEAL funding from the National Institute on Drug Abuse for the Southwest Clinical Trial Node of the NIDA Clinical Trials Network. We propose to conduct this work in southern New Mexico, an area with a highly diverse population, where many groups are impacted by OUD and there has been low clinical trial engagement. Using existing materials and resources, we will examine, adapt, and test these to produce a clinical research engagement toolkit that can be used to enhance engagement in clinical research by addressing both individual and structural barriers to engagement. The Health Beliefs Toolkit includes items that can be adapted to assess individuals’ knowledge of health, their perceived susceptibility to illness, and barriers (including personal values and beliefs) or benefits to health research engagement. We will review and adapt health literacy tools to develop ‘clinical research literacy’ tools for toolkit inclusion. We will also develop components that aim to enhance communication about clinical research with motivational interviewing techniques. Finally, we will develop an assessment of structural vulnerability adapted from the structural vulnerability checklist for health care providers. The target groups we will work with to adapt, develop and test the toolkit will include: primary care providers, promotora/es (community health workers), peer counselors, agency representatives, and patient and non-patient groups. We will use a mixed-methods approach to adaptation and evaluation of the proposed toolkit. Ripple Effects Mapping will be conducted as part of the final evaluation. The proposed EXPLORE toolkit project will use a novel web-based platform for project activities, community engagement, and evaluation.

抽象的 提高不同人群在临床研究中的包容性和参与度可以扩大临床研究的相关性和 由于将研究成果转化为实践，许多社区在健康研究中的代表性不足。 导致：缺乏对临床研究的了解、不信任、缺乏机会、地理位置和社会因素。 了解研究如何运作以及如何使社区受益是非 参与，特别是如果研究是在学术医疗机构和地方进行的 很大一部分人无法获得医疗服务，而社区卫生团体往往缺乏医疗服务。 有关临床研究的知识和培训，以及它如何与患者和社区保持一致或不一致 据我们所知，目前还没有旨在促进包容性和参与性的工具概要。 在此补充申请中，我们建议开发多样化和少数群体的临床研究。 该工具包的目标是为研究人员和社区合作伙伴提供使用指南。 在提出临床研究时，我们会考虑个人、文化和结构的观点。 对促进参与涉及物质使用的研究和试验特别感兴趣，并且 特别是阿片类药物使用障碍 (OUD)，与国家药物研究所的 HEAL 资助相关 NIDA 临床试验网络西南临床试验节点的滥用 我们建议进行此项活动。 在新墨西哥州南部工作，该地区人口高度多样化，许多群体都受到 OUD 和临床试验参与度较低，我们将利用现有材料和资源。 检查、调整和测试这些内容以生成可用于增强临床研究参与工具包 通过解决参与的个人和结构障碍来参与临床研究。 健康信念工具包包括可用于评估个人健康知识、健康状况的项目 感知到的疾病易感性以及对健康的障碍（包括个人价值观和信仰）或益处 我们将审查和调整健康素养工具，以开发“临床研究素养”工具。 我们还将开发旨在加强临床沟通的组件。 最后，我们将开展结构性评估。 脆弱性改编自卫生保健提供者的结构脆弱性清单。 将合作调整、开发和测试该工具包，其中包括：初级保健提供者、promotora/es （社区卫生工作者）、同伴咨询师、机构代表以及患者和非患者团体。 将使用混合方法来适应和评估拟议的涟漪效应。 绘制地图将作为最终评估的一部分进行。拟议的 EXPLORE 工具包项目将使用 用于项目活动、社区参与和评估的新型网络平台。