CACHET - Pilot Project

CACHET - 试点项目

• 批准号: 10394646
• 负责人: Gokhan M. Mutlu
• 金额: $ 22.18万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-30 至 2027-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10394646
• 关键词: Abbreviations; Address; Applications Grants; Area; Aryl Hydrocarbon Receptor; Award; Biological Markers; Cell physiology; Centers for Disease Control and Prevention (U.S.); Chicago; Clinical Sciences; Clinical and Translational Science Awards; Collaborations; Communities; Core Facility; Data; Development; Discipline; Environment; Environmental Exposure; Environmental Health; Environmental Risk Factor; Faculty; Focus Groups; Fostering; Funding; Funding Agency; Future; Grant; Growth; Health; Health Sciences; Illinois; Institution; Lead; Leadership; Mentors; Methods; Molecular; National Institute of Environmental Health Sciences; Occupational Health; Participant; Pilot Projects; Plant Roots; Program Development; Progress Reports; Public Health Schools; Publications; Request for Applications; Research; Research Personnel; Research Project Grants; Resources; SARS-CoV-2 infection; Testing; Time; Toxic effect; Translational Research; United States National Institutes of Health; Universities; Work; career; career development; clinical center; community based participatory research; community based research; community engagement; design; environmental justice; ethnic health disparity; health disparity; health science research; high reward; high risk; innovation; inter-institutional; member; next generation; non-alcoholic fatty liver disease; programs; racial and ethnic; recruit; response; success

1. PILOT PROJECT PROGRAM: ABSTRACT The ChicAgo Center for Health and EnvironmenT (CACHET) Pilot Project Program is designed to fund new directions in environmental health sciences (EHS) research and provide a primary mechanism for developing the careers of CACHET members. The Pilot Project Program is critical to promoting the success of CACHET investigators and the development of future CACHET resources in EHS research. Indeed, in the current abbreviated funding cycle, this program funded 28 pilot awards totaling $639,000 in research dollars to Center members. To date, these awards have directly led to five NIH-funded R01 and one K08 grants totaling $11,329,383, while five submitted grants are pending and four were submitted but not funded. Pilot projects awarded through this program explore new EHS research areas, build research collaborations and teams (within each institution, between the two institutions and externally), support the next generation of EHS researchers and accelerate external grant support of CACHET members. Proposals that consider data collected by the Community Engagement Core (CEC) as well as proposals that actively collaborate with CEC community participants are encouraged. This focus enables CACHET to directly address the environmental research needs of the community and, in so doing, undertake research aimed at mitigating racial and ethnic health disparities as a function of adverse environmental factors. Innovative and high-risk/high-reward studies are also encouraged. The Pilot Project Program has four primary award types: Young Investigator Award, Idea Award, Focused Research Award and Inter-Institutional Award; each addresses specific needs for building and supporting a strong EHS research community in Chicago. Proposals are reviewed for scientific merit, feasibility, community- relevance, and potential to lead to external grants in EHS research from NIEHS and other funding agencies. Funds awarded by the program are not only essential for cultivating the careers of junior investigators by enhancing their success in obtaining grants and publications, but also for attracting established investigators from other disciplines into the EHS research field and fostering new collaborations. We are confident that in the next five years, the Pilot Project Program will result in a substantial increase in NIEHS funding for CACHET investigators, will noticeably expand EHS research capacity in Chicago, fostering the next generation of EHS researchers and will meaningfully impact the local community.

1. 试点项目计划：摘要 芝加哥健康与环境中心 (CACHET) 试点项目计划旨在资助新的 环境健康科学（EHS）研究的方向，并提供发展的主要机制 CACHET 会员的职业生涯。试点项目计划对于促进 CACHET 的成功至关重要 EHS 研究中的研究人员和未来 CACHET 资源的开发。确实，在当前 该计划缩短了资助周期，向中心资助了 28 个试点项目，总计 639,000 美元的研究资金 成员。迄今为止，这些奖项已直接带来 NIH 资助的 5 项 R01 和 1 项 K08 资助，总计 11,329,383 美元，五项已提交的赠款正在等待处理，四项已提交但尚未获得资助。试点项目 通过该计划授予探索新的 EHS 研究领域、建立研究合作和团队（在 每个机构（两个机构之间以及外部）支持下一代 EHS 研究人员 并加速对 CACHET 成员的外部资助支持。考虑收集的数据的提案 社区参与核心 (CEC) 以及与 CEC 社区积极合作的提案 参与者受到鼓励。这一重点使 CACHET 能够直接满足环境研究需求 社区，并在此过程中开展旨在减轻种族和民族健康差异的研究 不利环境因素的作用。还鼓励创新和高风险/高回报的研究。 试点项目计划有四种主要奖项类型：青年研究者奖、创意奖、聚焦奖 研究奖和机构间奖；每个都解决了构建和支持一个特定的需求 芝加哥强大的 EHS 研究社区。对提案的科学价值、可行性、社区价值进行审查 相关性以及从 NIEHS 和其他资助机构获得 EHS 研究外部资助的潜力。 该计划授予的资金不仅对于培养初级研究人员的职业生涯至关重要 提高他们在获得资助和出版物方面的成功率，同时也吸引知名研究人员 来自其他学科的人员进入 EHS 研究领域并促进新的合作。我们有信心在 未来五年，试点项目计划将导致 NIEHS 对 CACHET 的资助大幅增加 研究人员将显着扩大芝加哥的 EHS 研究能力，培育下一代 EHS 研究人员并将对当地社区产生有意义的影响。