Modification and Renovation of Vivarium for the Advancement of Institutional Biomedical Research

为促进机构生物医学研究而对动物饲养场进行改造和翻新

• 批准号: 10374473
• 负责人: Andrea Gentry-Apple
• 金额: $ 513.07万
• 依托单位: NORTH CAROLINA AGRI & TECH ST UNIV
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-20 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10374473
• 关键词: Accreditation; Address; Agriculture; Animal Housing; Animal Model; Animals; Applications Grants; Biological; Biological Sciences; Biomedical Research; Communities; Faculty; Funding; Goals; Healthcare; Home; Institution; Laboratory Animal Production and Facilities; Modeling; Modernization; Modification; Noise; North Carolina; Pattern; Postdoctoral Fellow; Productivity; Research; Research Personnel; Research Project Grants; Research Proposals; Research Training; Resources; Safety; Science; Strategic Planning; Structure; Triad Acrylic Resin; United States National Institutes of Health; Universities; career; design; exhaust; faculty research; interest; programs; recruit; research facility; trend; undergraduate student

The proposed project will renovate North Carolina Agricultural and Technical State University’s (NCA&T) 38- year-old vivarium for use as a core research facility serving the university community and the Piedmont Triad region in central NC. This renovation is critically needed to address the vivarium’s structural and design issues that make it challenging to meet the needs of biomedical researchers, a group whose numbers are increasing at our institution. The requested funding will help drive this increase in biomedical research, breaking the Catch-22 predicament that limits faculty submission of federal grant proposals for research with animal subjects and constrains further expansion of our institution’s biomedical research enterprise. As a result of the vivarium’s outdated status, our researchers are using other facilities or changing their research agendas to alternative models. To reverse this trend and align with the university’s strategic plan and stated intent to attain R1 status, the project goals are to (1) renovate and redesign the existing vivarium to provide a modern environmentally-controlled unit, with noise reduction and an efficient cage washing facility and traffic pattern and (2) to create a near barrier facility with fixed exhaust ventilated cages and biological safety cabinets. Long-term impact of the proposed renovation will enable the expansion of biomedical, life science, and agricultural research at NCA&T and the Piedmont Triad region, which is home to a growing number of companies in the biosciences, pharma, and healthcare; and increase the advancement of undergraduate, doctoral and post-doctoral research training to increase regional, statewide and national diversity within biomedical sciences and careers. Renovation of the vivarium will enhance research programs across the institution by providing the resources needed to conduct biomedical research projects on campus in a core research animal facility versus seeking animal housing and ancillary support at other facilities. The renovated facility will also support increased research productivity by encouraging faculty to seek targeted external funding to grow their biomedical research portfolios incorporating animal models and by promoting recruitment of new research faculty with biomedical research interests. Additionally, the project will help us accomplish our long-term goal of achieving AAALAC accreditation. Per the four criteria at U.S.C. 42 Section 283k(c)(2), NCA&T declares its status as an Institution of Emerging Excellence (IEE). The renovated vivarium will help NCA&T elevate its status from an NIH- designated IEE to a research-intensive institution.

拟议项目将翻新北卡罗来纳州立农业技术大学 (NCA&T) 拥有 38 年历史的动物园，用作服务大学社区和社区的核心研究设施 北卡罗来纳州中部的皮埃蒙特三合会地区迫切需要进行这项改造，以解决动物园的问题。 结构和设计问题使得满足生物医学研究人员的需求具有挑战性， 我们机构的人数正在增加，所请求的资金将有助于推动这一目标。 生物医学研究的增加，打破了限制教师提交论文的第二十二条军规困境 用于动物研究的联邦拨款提案和限制进一步扩大我们的研究 由于动物园的陈旧状况，我们的生物医学研究企业。 研究人员正在使用其他设施或将他们的研究议程更改为替代模型。 扭转这一趋势并与大学的战略计划和获得 R1 地位的既定意图保持一致， 项目目标是 (1) 翻新和重新设计现有的动物园，以提供现代化的环境 环境控制装置，具有降噪功能和高效的笼子清洗设施和交通 (2) 创建具有固定排气通风笼和生物安全的近屏障设施 拟议改造的长期影响将使生物医学、生活的扩展。 NCA&T 和皮埃蒙特三合会地区的科学和农业研究，该地区是不断增长的 生物科学、制药和医疗保健领域的公司数量，并提高其进步； 本科生、博士生和博士后研究培训，以增加地区、联邦和 生物医学科学和职业领域的民族多样性。 动物园的翻新将通过提供以下资源来加强整个机构的研究项目： 在校园核心研究动物设施中开展生物医学研究项目所需的资源 与在其他设施中寻求动物饲养和辅助支持相比，翻新后的设施也将。 通过鼓励教师寻求有针对性的外部资金来支持提高研究生产力 扩大他们的生物医学研究组合，纳入动物模型并促进招募 此外，该项目将帮助我们完成生物医学研究的新研究人员。 我们的长期目标是获得 AAALAC 认证。 根据 U.S.C. 42 第 283k(c)(2) 条的四项标准，NCA&T 声明其作为机构的地位 新兴卓越 (IEE) 翻新后的动物园将帮助 NCA&T 提升其 NIH 地位。 指定 IEE 为研究密集型机构。