Core A: Administrative Core

核心A：行政核心

• 批准号: 10333055
• 负责人: Margaret A. Pericak-Vance
• 金额: $ 81.52万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10333055
• 关键词: Address; Advisory Committees; African; African American; Aging; Agreement; Alzheimer' s Disease; Awareness; Budgets; Clinical; Collaborations; Communication; Communities; Complex; Data; Data Set; Dementia; Development; Elements; Ensure; Feedback; Funding; Genetic; Genetic Predisposition to Disease; Genetic Research; Genetic Risk; Genetic Variation; Genomics; Goals; Head; Hispanic; Individual; Infrastructure; Institution; Institutional Review Boards; International; Latinx population; Lead; Logistics; Machine Learning; Minority; Minority Groups; Monitor; Nature; Neuropsychology; Not Hispanic or Latino; Occupational activity of managing finances; Participant; Persons; Population; Press Releases; Principal Investigator; Protocols documentation; Publications; Recommendation; Research; Research Personnel; Resources; Role; Sampling; Scientist; Site; Time; Underserved Population; United States National Institutes of Health; Videoconferencing; Work; cohort; data sharing; experience; functional genomics; genetic analysis; genetic architecture; human subject protection; inter-institutional; meetings; post-doctoral training; recruit; response; video chat; web site

ABSTRACT The large number of sites (14) and the international nature of the READD-ADSP proposal make the logistical, regulatory and financial aspects particularly complex. Core A, the administrative core, provides the necessary oversight, coordination, and administrative infrastructure for this proposal. Core A will oversee the regulatory and financial aspects of our international collaboration and assure broad data sharing. The proper sharing of data and samples being collected necessitates the execution of a number of institutional agreements and assurance that the proper IRBs are in place. Core A will ensure that all documents have been signed and IRB approval has been obtained prior to the transfer of samples. An experienced Director of Finance will oversee all financial aspects, with close interaction and collaboration with the individual Core, Project and Site PIs at the different READD-ADSP institutions. Core A will coordinate and integrate all READD-ADSP components and activities. In a study this large, frequent communication is imperative. Semi-monthly video conferences of the MPIs and investigators will be organized and managed by Core A. Core A will coordinate and organize internal executive and external scientific advisory committee meetings. An internal executive committee of all the MPIs will meet every other month to review progress and address any outstanding issues. An external scientific advisory committee comprised of individuals with relevant expertise will meet four times a year (one in- person) to provide feedback. Core A will support these meetings and ensure that any recommendations are implemented. Lastly, Core A will facilitate the interaction with scientific communities relevant to READD- ADSP goals as well as the lay public. A resource is only valuable if people are aware of it. Core A will assist investigators with publicizing their work through national/international meetings, publications, and press releases and through the development of a website. The website will also contain information geared to the lay audience, including highlights of research funding and participation opportunities. Core A will also interface with NIA to keep them apprised of findings and to implement any changes that NIA requests.

抽象的 READD-ADSP 提案的大量站点 (14) 和国际性质使得后勤、 监管和财务方面尤其复杂。核心 A，行政核心，提供必要的 该提案的监督、协调和行政基础设施。核心A将监督监管 我们的国际合作的财务方面，并确保广泛的数据共享。正确的分享 收集的数据和样本需要执行许多机构协议和 确保适当的 IRB 到位。核心 A 将确保所有文件均已签署且 IRB 样品转移前已获得批准。经验丰富的财务总监将监督所有 财务方面，与各个核心、项目和站点 PI 密切互动和协作 不同的 READD-ADSP 机构。核心 A 将协调和集成所有 READD-ADSP 组件， 活动。在一项研究中，这种大规模、频繁的沟通是必不可少的。每半个月召开一次视频会议 MPI 和调查员将由核心 A 组织和管理。核心 A 将协调和组织 内部执行和外部科学咨询委员会会议。内部执行委员会 所有 MPI 每隔一个月举行一次会议，审查进展情况并解决任何悬而未决的问题。一个外部 由具有相关专业知识的个人组成的科学咨询委员会每年举行四次会议（其中一位 人）提供反馈。核心 A 将支持这些会议并确保任何建议得到落实 实施的。最后，核心 A 将促进与 READD 相关科学界的互动 ADSP 目标以及公众。资源只有被人们意识到才有价值。核心A将协助 研究人员通过国内/国际会议、出版物和新闻稿宣传他们的工作 并通过网站的开发。该网站还将包含面向非专业受众的信息， 包括研究资助和参与机会的重点。 Core A 还将与 NIA 接口 让他们了解调查结果并实施 NIA 要求的任何变更。