FASEB's Mobile DNA: Evolution, Diversity, and Impact Conference.

FASEB 的移动 DNA：进化、多样性和影响会议。

• 批准号: 10317953
• 负责人: Victoria Perepelitsa Belancio
• 金额: $ 4万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-01 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10317953
• 关键词: Academy; Affect; Age; Aging; Binding Sites; Bioinformatics; Biological Assay; Biological Models; Biological Process; Biology; Biology of Aging; COVID-19 pandemic; Cell Survival; Chronic; Collaborations; Colorectal Cancer; Committee Members; Communication; Communities; Consensus; CpG dinucleotide; DNA Damage; DNA Repair; DNA Sequence Rearrangement; DNA Transposable Elements; Data Set; Development; Diagnosis; Disease; Elements; Ensure; Epigenetic Process; Europe; European; Event; Evolution; Experimental Models; Family Leave; Female; Fostering; Funding; Genes; Genetic; Genetic Variation; Genome; Genomic Instability; Genomics; Germ Lines; Geroscience; Goals; Grant; Health; Human; Human Genome; Immune; Immune response; Individual; Inflammation; Institutes; International; Investigation; Ireland; Leadership; Location; Longevity; Maintenance; Malignant Neoplasms; Minority Participation; Modeling; Mutation; National Institute of Drug Abuse; Nature; Nerve Degeneration; Neurons; Normal tissue morphology; Pathologic; Pathology; Persons; Phenotype; Play; Polyadenylation; Principal Investigator; Process; RNA Processing; RNA Splicing; Recording of previous events; Repetitive Sequence; Research; Research Personnel; Role; Schedule; Science; Scientist; Signal Transduction; Site; Somatic Cell; Source; Students; System; Techniques; Technology; Testing; Thinking; Time; Tissues; Travel; United States National Academy of Sciences; United States National Institutes of Health; age related; base; career; career development; circadian; coronavirus disease; deep sequencing; experience; functional decline; genomic variation; high throughput technology; human disease; improved; innovation; interdisciplinary collaboration; interest; mammalian genome; meetings; member; minority scientist; nervous system disorder; neuronal cell body; normal aging; novel; outreach program; pandemic disease; posters; prevent; programs; promoter; recruit; response; senescence; symposium; tool; transcription factor; transposon/insertion element; trend; virtual

Mobile elements continue to play a major role in restructuring their host genomes. Since the discovery of transposons, the main focus has been on their contribution to germ line diseases, which is proven to be relevant to human health. The major departure of the 2021 FASEB conference from this line of thinking is its focus on the TE contribution to somatic genetic variation and its impact on normal aging and age-associated diseases, specifically those involving transformation or degeneration. Integration of this research direction into the FASEB “Mobile DNA: Evolution, Diversity, and Impact” meeting sets it apart from previous FASEB conferences as well as other TE- and aging-related meetings. Three members of the organizing committee, including the organizer of the conference, are NIA-funded investigators. One member of the committee, Dr. Steven Austad, is a prominent member of the aging field. Four US National Academy of Sciences members and two members of the European Academy of Sciences agreed to present at the conference and participate in the career development and meet-the-expert sessions. Our 2021 FASEB conference was scheduled for June 6-9 in Dublin, Ireland. Having an international location for the first time in the history of this conference is beneficial because both fields are strong in Europe. The European location will also make travel easier (i.e. fewer visa restrictions) and less expensive, which will increase attendance. In response to COVID the FASEB has changed the format to a 2- day virtual conference in June 8-9, 2021, followed by the traditional on-site conference in June 5-9, 2022. This format is beneficial to our goals of establishing and fostering collaborations between the two fields of research.

自从发现以来，移动元件在重组宿主基因组方面继续发挥着重要作用。 转座子，主要关注点是它们对种系疾病的贡献，这已被证明是相关的 2021 年 FASEB 会议与这一思路的主要区别在于其重点关注 TE 对体细胞遗传变异的贡献及其对正常衰老和年龄相关疾病的影响， 特别是涉及将该研究方向整合到 FASEB 中的领域。 “移动 DNA：进化、多样性和影响”会议也与之前的 FASEB 会议不同 与其他 TE 和老龄化相关的会议一样，三名组委会成员，包括组织者。 该委员会的成员之一史蒂文·奥斯塔德 (Steven Austad) 博士是 NIA 资助的研究人员。 老龄化领域的杰出成员，四名美国国家科学院院士和两名美国国家科学院院士。 欧洲科学院同意出席会议并参与职业发展 我们的 2021 年 FASEB 会议定于 6 月 6 日至 9 日在爱尔兰都柏林举行。 本次会议历史上首次在国际上举办是有益的，因为这两个领域 欧洲的地位也将使旅行变得更容易（即签证限制更少）并且更少。 昂贵，这将增加出席人数，FASEB 已将格式更改为 2- 2021 年 6 月 8 日至 9 日举行一天虚拟会议，随后于 2022 年 6 月 5 日至 9 日举行传统现场会议。 这种形式有利于我们建立和促进两个研究领域之间合作的目标。