Wyoming Sensory Biology COBRE

怀俄明州感官生物学 COBRE

• 批准号: 10216275
• 负责人: Qian-Quan Sun
• 金额: $ 200.41万
• 依托单位: UNIVERSITY OF WYOMING
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10216275
• 关键词: Address; Antibodies; Area; Basic Science; Behavior; Biology; Biomedical Research; Centers of Research Excellence; Collaborations; Core Facility; Development; Equilibrium; Faculty; Fostering; Functional disorder; Funding; Future Teacher; Goals; Image; Impairment; Interdisciplinary Study; Journals; Laboratory Research; Leadership; Learning Disorders; Link; Manuscripts; Mentors; Methodology; Microscopy; Mission; Modality; Molecular; Molecular Analysis; National Institute on Deafness and Other Communication Disorders; Obesity; Peer Review; Physiological; Process; Publications; Publishing; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Support; Role; Sensory; Sensory Disorders; Sensory Process; System; Training; Translational Research; United States; United States National Institutes of Health; Universities; Vision; Wyoming; chronic pain; experience; interest; multidisciplinary; operation; recruit; sensory neuroscience; sensory stimulus; sensory system; success; visual learning; web site

Abstract The primary mission of the Wyoming Sensory Biology COBRE (SBC) is to foster and conduct high-quality scientific research that advances the understanding of our sensory systems and disorders related to them. SBC will accomplish its mission through the augmentation and strengthening of UW's institutional biomedical research capacity. This will be accomplished through building a critical mass of investigators whose research interests center around sensory processes at the molecular, cellular, physiological and system levels. SBC will promote the competitiveness of the core investigators by providing mentoring, training, collaboration and research support. The SBC will be led by the PI with the help of an excellent group of additional mentors. The PI is an established sensory system investigator with expertise that is germane to the research theme of the center, has an active research laboratory, has obtained peer-reviewed funding and has extensive administrative leadership and mentoring experience. The SBC is comprised of the Administration Core, the Integrated Microscopy Core (IMcore), and four interrelated research projects. As a whole, the SBC will support four new junior investigators and four future faculty hires that are committed to the SBC, during the five years of the COBRE funding. The Center will comprise a multi-disciplinary team of investigators with expertise across multiple sensory modalities, including somatosensation, chemosensation, and vision. The SBC investigators' research portfolios demonstrate a balance of basic and translational research across multiple fields. The five-year goals of the SBC are the following: 1. Establish a multi- disciplinary center that brings together investigators with expertise in diverse areas of sensory neuroscience and experimental methodology, and fosters collaborations to address key issues in sensory function and dysfunction. 2. Support the projects of junior investigators by providing strong mentoring and guidance to help them obtain independent funding and professional success. 3. Grow the SBC in both size and scope through the recruitment of new faculty, as described in the Institutional Commitment, and fostering multi-disciplinary research among current UW faculty, respectively. 4. Build the required research infrastructure by expanding the capabilities of the Microscopy Core. 5. Advance our understanding of the development and function of sensory systems and their dysfunctions. Successful operation of the Center is expected to achieve the following milestones within the initial five years of funding: successful expansion of a state-of-the-art imaging and microscopy core facility, all four Project Leaders successfully competing for R01-level funding; four to six new or early-stage investigators added to the Center; two to four new mentors added (including Project Leaders who recently graduated from COBRE support); and at least 20 manuscripts accepted for publication or published in reputable peer-reviewed journals.

抽象的 怀俄明州感觉生物学 COBRE (SBC) 的主要使命是培养和开展 高质量的科学研究促进了我们对感官系统的理解和 与他们相关的疾病。 SBC 将通过增强和 加强华盛顿大学生物医学研究机构的能力。这将实现 通过建立一批关键的研究人员，他们的研究兴趣集中在感官上 分子、细胞、生理和系统水平的过程。 SBC将推动 通过提供指导、培训、协作和 研究支持。 SBC 将由 PI 领导，并得到优秀团队的帮助 导师。 PI 是一位成熟的感觉系统调查员，其专业知识与 该中心的研究主题，拥有活跃的研究实验室，已获得同行评审 资金并拥有丰富的行政领导和指导经验。 SBC 是 由管理核心、集成显微镜核心 (IMcore) 和四个 相互关联的研究项目。总体而言，SBC 将支持四名新的初级调查员和 在 COBRE 的五年内，将聘用四名未来的教员，致力于 SBC 资金。该中心将由具有跨领域专业知识的多学科研究人员组成 多种感觉方式，包括体感、化学感觉和视觉。南美银行 研究人员的研究组合展示了基础研究和转化研究的平衡 跨越多个领域。 SBC 的五年目标如下： 1. 建立多方合作机制 学科中心汇集了具有不同感官领域专业知识的研究人员 神经科学和实验方法，并促进合作解决关键问题 感觉功能和功能障碍。 2. 支持初级研究者的项目，提供 强有力的指导和指导，帮助他们获得独立的资金和专业的帮助 成功。 3. 通过招聘新教师来扩大 SBC 的规模和范围， 机构承诺中所述，并促进跨学科研究 现任华盛顿大学教师。 4. 通过扩大研究范围来建设所需的研究基础设施 显微镜核心的功能。 5. 加深我们对发展的理解 感觉系统的功能及其功能障碍。中心的成功运作是 预计在资助的最初五年内实现以下里程碑： 成功 扩建最先进的成像和显微镜核心设施，所有四位项目负责人 成功竞争R01级资助；增加了四到六名新的或早期研究人员 前往中心；添加了两到四名新导师（包括最近毕业的项目负责人） 来自 COBRE 支持）；以及至少 20 篇稿件被接受发表或发表于 著名的同行评审期刊。