Animal Models and Phenotyping Core

动物模型和表型核心

基本信息

批准号：
10208902
负责人：
Daniel Joseph Conklin
金额：
$ 19.76万
依托单位：
UNIVERSITY OF LOUISVILLE
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-07-01 至 2023-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10208902
关键词：
Animal Model Animals Capital Cardiometabolic Disease Cardiovascular system Centers of Research Excellence Complex Complications of Diabetes Mellitus Consultations Consumption Continuing Education Core Facility Country Development Diabetes Mellitus Educational workshop Equipment Evaluation Fees Funding Future Grant Human Resources Infrastructure Institution Instruction Insulin Resistance Investments Learning Marshal Metabolic Metabolism Methods Modeling Molecular National Heart, Lung, and Blood Institute National Institute of Environmental Health Sciences Obesity Phase Phenotype Procedures Protocols documentation Research Research Personnel Resource Sharing Resources Series Services Standardization Structure Study models Superfund Techniques Technology Time Training Training Activity Universities animal imaging base career career development detection method expectation experience instrument investigator training lectures member metabolomics pre-clinical programs success user-friendly

项目摘要

The function of the Animal Core of the University of Louisville’s Diabetes and Obesity Center (DOC) is to provide members of the DOC with the resources, facilities and knowhow needed for the development, interrogation and phenotyping of animal models for diabetes and obesity research using state-of-the-art techniques, procedures and protocols relevant to the evaluation of metabolism and assessment of adiposity, insulin resistance, and the cardiovascular complications of diabetes. By successive accumulation of expertise, resources, and experience, the Core has become an integral component of the Center and an indispensable resource for diabetes and obesity research, comparable with research cores at leading institutions around the country. Developing on this trajectory of success, the Core will continue to provide unique and unduplicated services to UofL investigators, and continue to grow by progressively acquiring and accumulating new capabilities, resources, and expertise.

路易斯维尔大学糖尿病和肥胖中心 (DOC) 动物核心的职能是为DOC成员提供发展所需的资源、设施和专业知识，使用最先进的技术对糖尿病和肥胖研究的动物模型进行询问和表型分析与代谢评估和肥胖评估相关的技术、程序和方案，胰岛素抵抗和糖尿病心血管并发症通过不断积累的专业知识，资源和经验，核心已成为中心的组成部分和不可或缺的糖尿病和肥胖研究的资源，可与世界各地领先机构的研究核心相媲美沿着这条成功的轨迹发展，核心将继续提供独特的、不可复制的产品。为伦敦大学调查人员提供服务，并通过逐步获取和积累新的资源来不断发展能力、资源和专业知识。