Ring-Strain Relief: Applications in Total Synthesis

环应力消除：全合成中的应用

• 批准号: DP200100722
• 负责人: Prof Mark Rizzacasa
• 金额: $ 9.48万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2020
• 资助国家: 澳大利亚
• 起止时间: 2020-01-01 至 2022-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP200100722
• 关键词: Ring; Strain; Relief; Applications; Total

This proposal aims to investigate the chemical synthesis of a number of structurally different natural product target molecules by strategies involving the use of either three or four membered ring-strained compounds to afford key synthetic intermediates in an efficient manner. The key aim of this research is to provide more efficient routes to complex natural products and analogues. The research strives to be at the forefront of modern synthetic organic chemistry and aims to contribute to the Science of complex molecule synthesis.

该提案旨在通过涉及使用三种或四个成员的环形化合物来提供有效的合成中间体的策略来研究许多结构上不同的自然产物目标分子的化学合成。这项研究的主要目的是为复杂的天然产品和类似物提供更有效的途径。该研究致力于成为现代合成有机化学的最前沿，并旨在为复杂分子合成的科学做出贡献。