FLYBASE--A DROSOPHILA RELATIONAL DATABASE

Flybase——果蝇关系数据库

• 批准号: 2208999
• 负责人: WILLIAM MARTIN GELBART
• 金额: $ 42.72万
• 依托单位: HARVARD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-08-01 至 1995-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2208999
• 关键词: Drosophilidae; RNA; chromosomes; clone cells; complementary DNA; computer program /software; genome; information systems; nucleic acid sequence; transposon /insertion element; Drosophilidae; RNA; chromosomes; clone cells; complementary DNA; computer program /software; genome; information systems; nucleic acid sequence; transposon /insertion element

The goal of this project is to develop a database of the Drosophila genome as a resource for the scientific community. The great utility and special advantages of Drosophila as an experimental system has been reflected in its choice as one of the few model organisms for the Human Genome Initiative. The information available on Drosophila genetics and molecular biology is already overwhelming, and new global research projects, such as those supported by the Human Genome Office promise to make huge amounts of new data available to the community. In the past, databases have been prepared as flat file catalogs of existing information on some aspects of the Drosophila genome. It is the view of this proposal that it is now essential to the continued exploitation of Drosophila as a model system to develop a continuously curated database of the most important information on the Drosophila genome. In this multi-site collaboration, we propose to develop a research resource which will meet this need. 1. We will develop a relational database structure, which we will call FlyBase, for the Drosophila genome. 2. We will set up a curatorial system for continuously incorporating new information on the Drosophila genome, with assigned responsibilities for the various data tables. at four university locations. 3. We will develop structures, query systems and front ends for the retrieval of information from FlyBase. 4. We will distribute FlyBase to the community in several fashions. It will be accessible on-line, by distribution by CD-ROM or other electronic media, and by occasional hard copy excerpts comprising issues of the Drosophila Information Service (DIS).

该项目的目的是开发果蝇的数据库 基因组是科学界的资源。 伟大的实用程序和 果蝇作为实验系统的特殊优势已经 反映在其选择中是人类的少数模型生物之一 基因组倡议。 有关果蝇遗传学和的信息 分子生物学已经压倒了，新的全球研究 像人类基因组办公室支持的项目有望 为社区提供大量新数据。 在过去， 数据库已作为现有的平面文件目录准备 有关果蝇基因组某些方面的信息。 这是 这项提出的提议现在对继续剥削至关重要 果蝇作为建立连续策划数据库的模型系统 关于果蝇基因组的最重要信息。 在这个 多站点协作，我们建议开发一种研究资源 将满足这种需求。 1。我们将开发一个关系数据库结构，我们将调用该结构 Flybase，用于果蝇基因组。 2。我们将建立一个策展系统，用于连续合并新的 有关果蝇基因组的信息，并具有分配的责任 各种数据表。在四个大学地点。 3。我们将开发结构，查询系统和前端 从Flybase检索信息。 4。我们将以几个时尚的方式向社区分发飞行案。 它 通过CD-ROM或其他电子的分配可以在线访问 媒体，以及偶尔的硬拷贝摘录，包括 果蝇信息服务（DIS）。