Comorbidity: Substance Use Disorders and Other Psychiatric Conditions

合并症：药物使用障碍和其他精神疾病

• 批准号: 10176435
• 负责人: MATT G KUSHNER
• 金额: $ 30.66万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10176435
• 关键词: Substance Use Disorder; comorbidity

Abstract Introduction: This is a renewal application for T32 institutional training grant application – Comorbidity: Substance Use Disorders and Other Psychiatric Conditions (NIDA DA037183) -- following the completion of its first five-year funding cycle. Among the current portfolio of NIDA funded training grants, only one program other than ours (Dartmouth) has comorbidity as a primary focus. This is striking given co-occurrence prevalence of Substance Use Disorders (SUD) with other psychiatric conditions and health conditions (e.g. diabetes), and the extent to which either SUD or the comorbid disorder can go under- or untreated in conventional treatment settings. The goals, elements and resources of the renewal program retains critical and effective elements of the initial funding period while incorporating important lessons learned. Long term goals: The proposed program will develop a cadre of scientists with research expertise in comorbidity mechanisms, antecedents and correlates, diagnostics, and psychosocial and pharmacological interventions. Component objectives are to provide each trainee with a working knowledge of comorbidity research including: (a) translational science from Early Phase Clinical Trials to Community Based Participatory Research perspectives; (b) effective research strategies for comorbid conditions across populations and ethnic and cultural groups (e.g. American Indian, Hmong, Somali). Accomplishing programmatic features will capitalize on (a) the spectrum of faculty expertise providing mentoring across multiple areas, and (b) integration across training programs and departments. Key Elements: (1) Involvement of scientists and clinicians with diverse expertise and a core internal advisory group. Primary sites (4 postdoctoral trainees, 2 yrs each) are the Departments of Psychiatry and Psychology (UMN Twin Cities) and Family Medicine and Biobehavioral Health (UMN Duluth); (2) Recruitment, including under represented group outreach, of rigorously screened PhD and MD candidates with SUD and comorbidity as primary career focus; (3) Training with an interdisciplinary mentoring team (primary & 2 secondary mentors) with complementary expertise; (4) Formal training plans with clear milestones including trainee development of an NIH application initiated in Year 1; (5) Active research, seminars, didactic course work, workshops, and development of management, ethics, and regulatory expertise; (6) Dynamic program administration entailing monitoring with enhancements and problem resolution along with continued contact with trainees after completion and; (7) Annually convened external advisory group. Resources: Mentor funding sources include NIH Institutes, NSF, Minnesota Medical Foundation, and pharmaceutical industry. Key Personnel and Primary Mentors are directors of clinics, centers, or departments with significant resources.

抽象的 简介：这是T32机构培训补助金申请的续签申请——合并症： 物质使用障碍和其他精神疾病（NIDA DA037183）——在其完成后 第一个五年资助周期中，NIDA 资助的培训补助金组合中只有一个项目。 除了我们（达特茅斯）以外，其他大学都将合并症作为主要关注点，考虑到同时发生的情况，这是令人震惊的。 药物滥用障碍 (SUD) 与其他精神疾病和健康状况（例如，精神疾病）的患病率 糖尿病），以及 SUD 或合并症的治疗不足或未治疗的程度 更新计划的目标、要素和资源保留了关键和重要的内容。 初始资助期的有效要素，同时纳入重要的长期目标： 拟议的计划将培养一支在合并症机制方面具有研究专业知识的科学家骨干队伍， 前因和相关性、诊断以及心理和药物干预。 目标是为每位学员提供共病研究的实用知识，包括：(a) 从早期临床试验到社区参与性研究的转化科学 (b) 针对不同人群和种族的共病状况的有效研究策略 文化群体（例如美洲印第安人、苗族、索马里人）将利用这一点实现纲领性特征。 (a) 教师专业知识范围广泛，提供跨多个领域的指导，以及 (b) 跨领域的整合 培训计划和部门的关键要素： (1) 科学家和多元化的参与。 专业知识和核心内部咨询小组（4 名博士后实习生，每人 2 年）是。 精神病学和心理学系（UMN 双城）以及家庭医学和生物行为健康系 （UMN 德卢斯）；(2) 招募经过严格筛选的博士和 以 SUD 和合并症为主要职业重点的医学博士候选人 (3) 跨学科培训； 具有互补专业知识的导师团队（主要导师和 2 位二级导师） (4) 正式培训计划； 明确的里程碑，包括第一年启动的 NIH 应用程序的实习生开发；(5) 积极的研究； 研讨会、教学课程、讲习班以及管理、道德和监管方面的发展 (6) 动态计划管理，需要加强监控和解决问题 以及在完成后与学员的持续联系； (7) 每年召开外部咨询会议 资源：导师资金来源包括 NIH 研究所、NSF、明尼苏达医学基金会和 制药行业的关键人员和主要导师是诊所、中心或部门的主任。 拥有大量资源。