Graduate Training in Molecular and Cellular Pharmacology

分子和细胞药理学研究生培训

• 批准号: 10175159
• 负责人: Anjon Audhya
• 金额: $ 48.76万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10175159
• 关键词: Molecular; Pharmacology; Training

Program Summary The main objectives of Graduate Training in Molecular and Cellular Pharmacology (GTMCP) at the University of Wisconsin (UW)-Madison are to provide predoctoral-level training in interdisciplinary research at the forefront of quantitative and systems pharmacology and a nucleus around which interdepartmental faculty, students, and scientists from across campus can meet and collaborate. Its overall mission is to provide a highly diverse group of trainees with the skills necessary to enter careers related to the Pharmacological Sciences in academia, industry, government, science education, and public policy. Discovering new approaches to drug delivery and developing novel drugs as therapeutics are cornerstones of the program, with a major emphasis on understanding pathways that are relevant to disease. To accomplish these goals, the curriculum focuses on delivering foundational knowledge in Pharmacology, including mechanisms of drug action, pharmacokinetics, and pharmacodynamics, stressing quantitative thinking and the value of -omic technologies. Carefully evaluated coursework centered on the importance of rigor and reproducibility, responsible conduct of research, safety within the laboratory, and grant writing promote the development of trained PhD scientists who can contribute to the biomedical research workforce. A core group of 29 dedicated faculty trainers has been assembled for this application, representing 10 departments, whose interests focus on understanding molecular, cellular, and physiological mechanisms by which drugs or natural ligands interact with cellular receptors and elicit effects in biological systems. All trainers have robust research programs and were selected based on a demonstrated commitment to mentoring graduate students in Pharmacology. Faculty members work in the interdisciplinary areas of Neuropharmacology, Cancer Pharmacology, Cardiovascular Pharmacology, Endocrine Pharmacology, and Immunopharmacology, and collaborate extensively with one another to create a highly interactive network. Each trainer has received extensive mentor training and understands the importance of strong mentor-mentee relationships in establishing an inclusive and supportive research environment. GTMCP leverages strong institutional support and substantial resources to facilitate the professional development of its trainees. Through its well-funded seminar series, all trainees are provided regular opportunities to develop excellent oral presentation skills and invite outside faculty speakers from top institutions across the country. Research retreats and symposia offer additional opportunities for students to host and interact with prominent members of the Pharmacology community and develop networking skills. GTMCP also boasts considerable trainee diversity, a high retention rate, a rapid time to degree, and an excellent record of trainee publications. Ten slots to support trainees for two years of their early graduate education are requested based on the growing demand for PhD- level scientists trained in Pharmacology and the high quality of students that apply to UW-Madison.

计划概要 大学分子和细胞药理学（GTMCP）研究生培训的主要目标 威斯康星大学麦迪逊分校将提供前沿跨学科研究的博士前水平培训 定量和系统药理学以及跨部门教师、学生和人员围绕的核心 来自整个校园的科学家可以见面并合作。其总体使命是提供高度多元化的团队 具有进入学术界药理学科学相关职业所需技能的学员， 工业、政府、科学教育和公共政策。发现药物输送的新方法 开发新药作为治疗方法是该计划的基石，重点是 了解与疾病相关的途径。为了实现这些目标，课程重点是 提供药理学基础知识，包括药物作用机制、药代动力学、 和药效学，强调定量思维和组学技术的价值。仔细评估 课程重点是严谨性和可重复性、负责任的研究行为、安全性的重要性 在实验室内，资助写作促进了受过训练的博士科学家的发展，他们可以为 生物医学研究人员。为此，我们组建了一个由 29 名专职教师培训师组成的核心团队 应用程序，代表 10 个部门，其兴趣集中于了解分子、细胞和 药物或天然配体与细胞受体相互作用并引起效应的生理机制 生物系统。所有培训师都有强大的研究计划，并根据经过论证的结果进行选择 致力于指导药理学研究生。教职员工在跨学科领域工作 神经药理学、癌症药理学、心血管药理学、内分泌药理学等领域 和免疫药理学，并相互广泛合作，创建一个高度互动的网络。 每位培训师都接受过广泛的导师培训，并了解强有力的导师的重要性 建立包容性和支持性研究环境的关系。 GTMCP杠杆强大 机构支持和大量资源，以促进学员的专业发展。通过 其资金充足的研讨会系列，为所有学员提供定期发展优秀口语的机会 演讲技巧并邀请来自全国顶尖机构的外部教师演讲。研究静修 和研讨会为学生提供了额外的机会主持并与杰出成员互动 药理学社区并培养网络技能。 GTMCP 还拥有相当大的学员多样性， 高保留率、快速获得学位以及优秀的实习出版物记录。支持十个插槽 由于对博士的需求不断增长，要求实习生接受两年的早期研究生教育 接受过药理学培训的科学家水平和申请威斯康星大学麦迪逊分校的学生质量很高。