Administrative Core

行政核心

基本信息

批准号：
10172080
负责人：
DEDRA S BUCHWALD
金额：
$ 52.14万
依托单位：
WASHINGTON STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-01 至 2026-04-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10172080
关键词：
Advisory Committees Alaska Native Alzheimer&apos s Disease Alzheimer&apos s disease related dementia American Indians Appointment Biology Budgets Businesses Clinical Trials Data Monitoring Committees Collaborations Collection Communication Communities Community Actions Computers Doctor of Philosophy Education Ensure Evaluation Faculty Genetic Goals Health Health care facility Human Resources Institution Institutional Review Boards International Lead Leadership Logistics Medicine Mental Health Minnesota Minority Groups Mission Monitor National Institute on Aging Native Hawaiian Neighborhood Health Center Neurology Oral Pacific Island Americans Policies Population Research Preparation Principal Investigator Process Publications Regulation Research Research Activity Research Methodology Research Personnel Research Project Grants Research Support Rural Scholarship Scientist Site Specialist Supervision Travel Tribes Underrepresented Minority Underrepresented Populations Underserved Population Universities Washington Work base brain health career development college community organizations data sharing decision research experience health disparity implementation facilitation meetings operation outreach physical conditioning professor programs recruit urban Native American

项目摘要

ADMINISTRATIVE CORE: ABSTRACT Natives Engaged in Alzheimer’s Research (NEAR) will be organized into an Administrative Core, a Recruitment and Engagement Core, a Biospecimen Core, a Research Methods Core, and 3 Research Projects. We will also incorporate a nationwide network of 8 Satellite Centers led by American Indian/Alaska Native and Native Hawaiian/Pacific Islander investigators who will assist with outreach, recruitment, and biospecimen collection. The contact Principal Investigator and Administrative Core Leader of NEAR, Dedra Buchwald, MD, Professor of Medicine at Washington State University, is widely recognized for her research, experience, and leadership in Alzheimer’s disease and related dementias in Native communities, and for her ongoing efforts to eliminate health disparities. She is the Founding Director of Partnerships for Native Health, a program of culturally appropriate research that has established 150+ partnerships with various Native entities in a 15-state region, including tribes, Indian health facilities, and organizations serving American Indians, Alaska Natives, Native Hawaiians, and Pacific islanders. Dr. Buchwald will be joined by James Galvin, MD, MPH, Professor, University of Miami, who will serve as the Scientific Director of NEAR and as a Multiple Principal Investigator and by John Kauwe, PhD, who will also serve as a Multiple Principal Investigator and as Co-Leader of the Biospecimen Core. This Core will integrate the contributions of 6 academic partner institutions, all of which have experience collaborating with American Indian/Alaska Native and Native Hawaiian/Pacific Islander, and other underrepresented minority populations, and with strengths in administration, research methods, scholarship, community-informed research, field work, and dissemination. Notably, our 3 Research Projects include 11 tribes, 7 urban Indian programs, an AI-owned small business, and 5 Native Hawaiian-serving community organizations. Our Specific Aims are to: 1) Support logistical and field operations across academic sites, including coordination of meetings and travel, and facilitate interactions with the Satellite Centers; 2) Oversee a plan for management, organization, and communication that stimulates, coordinates, integrates, and monitors activities and functions across and among all NEAR Research Projects, Cores, faculty, and institutions; 3) Supervise and facilitate implementation of key strategic decisions, research regulatory processes, and data sharing plans; 4) Collaborate on program planning, review, and evaluation to ensure that NEAR achieves its goals and maintains its focus on population-based research in Alzheimer’s disease and related dementias-related health disparities; and 5) Convene the Executive Committee, the External Advisory Committee, the Publications and Presentations Committee, the Data Safety and Monitoring Board, and the Community Action Board. The latter will include diverse stakeholders and guide researchers on local cultural concerns and solutions. In summary, the Administrative Core will manage, coordinate, and supervise the entire range of activities; monitor progress; ensure that component plans are implemented; and verify that all NEAR-supported research is carried out in compliance with Federal regulations and policies. Together, NEAR committees and activities will ensure the successful implementation of all efforts.

行政核心：摘要从事阿尔茨海默病研究的当地人 (NEAR) 将被组织成一个行政核心、一个招募团队我们还将开展参与核心、生物样本核心、研究方法核心和 3 个研究项目。合并由美洲印第安人/阿拉斯加原住民和原住民领导的 8 个卫星中心组成的全国网络夏威夷/太平洋岛民调查员将协助外展、招募和生物样本收集。联系人 NEAR 首席研究员兼行政核心领导者 Dedra Buchwald 医学博士、教授华盛顿州立大学医学博士，因其在医学领域的研究、经验和领导力而受到广泛认可土著社区的阿尔茨海默病和相关痴呆症，以及她为消除健康问题所做的持续努力她是土著健康合作伙伴关系的创始董事，该计划是一个适合文化的项目。研究已与 15 个州地区的各种原住民实体（包括部落）建立了 150 多个合作伙伴关系，印第安人医疗机构和组织为美洲印第安人、阿拉斯加原住民、夏威夷原住民和太平洋岛民、迈阿密大学教授詹姆斯·加尔文 (James Galvin) 也将加入其中。将担任 NEAR 的科学总监和多项首席研究员，约翰·考威 (John Kauwe) 博士，他还将担任多项首席研究员和生物样本核心的联合领导者。将整合 6 个学术合作机构的贡献，所有这些机构都有与美洲印第安人/阿拉斯加原住民和夏威夷原住民/太平洋岛民以及其他代表性不足的少数民族人口，并在管理、研究方法、学术、社区知情研究方面具有优势，值得注意的是，我们的 3 个研究项目包括 11 个部落、7 个城市印第安项目、一家人工智能拥有的小型企业，以及 5 个为夏威夷原住民服务的社区组织。的目的是： 1) 支持跨学术场所的后勤和现场运作，包括协调会议和旅行，并促进与卫星中心的互动； 2) 监督管理、组织和管理计划；促进、协调、整合和监控跨部门和部门之间的活动和职能的沟通所有 NEAR 研究项目、核心、教员和机构 3) 监督和促进关键的实施 4) 协作进行项目规划，审查和评估，以确保 NEAR 实现其目标并保持对基于人口的关注阿尔茨海默病和相关痴呆症相关的健康差异研究；以及 5) 召集执行委员会；委员会、外部咨询委员会、出版物和演示委员会、数据安全监督委员会和社区行动委员会，后者将包括不同的利益相关者并提供指导。研究当地文化问题和解决方案的研究人员总而言之，行政核心将管理：协调并监督整个活动的进展；实施；并验证所有 NEAR 支持的研究均符合联邦法规 NEAR 委员会和活动将共同确保所有努力的成功实施。