PEDIATRIC BODY COMPOSITION--ETHNIC SPECIFICITIES

儿科身体成分——种族特征

• 批准号: 2140078
• 负责人: RICHARD N PIERSON
• 金额: $ 37.29万
• 依托单位: ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-08-01 至 1999-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2140078
• 关键词: African American; Asian Americans; adolescence (12-20); age difference; body composition; body physical characteristic; body water; body weight; caucasian American; electrical impedance; ethnic group; fats; gender difference; health surveys; human puberty; human subject; middle childhood (6-11); pediatrics; photon absorptiometry; potassium; questionnaires; racial /ethnic difference; saliva

Results obtained from phases I and II of the Rosetta stone project for body composition (BC) in White, Black and Asian adults have shown that measurements of BC are strongly influenced by age, sex, race, and choice of method. Also, the traditional methods for measuring BC based on the assumed constants of potassium, water, or density of the fat free mass, give erroneous results because these "constants" vary by sex, age, race and health status. Studying fatness by applying complementary techniques orthogonal to one another, we have developed translation tables between the traditional and new methods. We have also studied anthropometrics and BIA, as surrogate methods for field uses, and we have mapped the compartmental relationships of fat and the f at free body as functions of aging in healthy adults. These results have been used as norms for the interpretation of BC measurements in patients with AIDS, obesity, paraplegia and aging. A similar study for children and adolescents is needed. We propose to perform our standard BC measurements: total body potassium, water, dual photon absorptiometry, bioimpedance analysis, electrical capacitance, anthropometry and underwater weighing, in White, Black and Asian children aged 6 to 18 years, an extension of our previous studies in adults. We shall generate standards based on sex, age, race and pubertal stage for body fat, fat free mass, bone mineral and density, and other derived descriptors of BC will be extended. We shall develop translation tables between methods and validate surrogate methods for children as we have for adults. A second and compelling motive for extending these studies to children is to enhance the quality of clinical care and the underlying research applications from which pediatricians and their patients may benefit. Our summary publication for the completed study of approximately 2000 volunteer adults and the 1170 studies in children and adolescents this project will add will be designed to serve workers in nutrition, physiology, pediatrics, aging, and the other research communities where body composition parameters are required.

从Rosetta Stone项目的I和II阶段获得的结果 白色，黑人和亚洲成年人的成分（BC）表明 卑诗省的测量受到年龄，性别，种族和选择的强烈影响 方法。 另外，基于 假定的钾，水或无脂肪质量密度的常数， 给出错误的结果，因为这些“常数”因性别，年龄，种族和 健康状况。 通过应用互补技术研究肥胖 彼此正交，我们已经开发了翻译表 传统和新方法。 我们还研究了人类学和BIA， 作为现场用途的替代方法，我们已经映射了隔室 脂肪和自由体的F作为衰老的功能 健康的成年人。 这些结果已被用作规范 解释艾滋病，肥胖症患者的BC测量 截瘫和衰老。 针对儿童和青少年的类似研究是 需要。 我们建议执行我们的标准BC测量：总体钾， 水，双光子吸收法，生物阻抗分析，电气 电容，人体测量法和水下称重，白色，黑色和 6至18岁的亚洲儿童，我们先前的研究延伸 成年人。 我们将根据性别，年龄，种族和青春期产生标准 体内脂肪，无脂肪质量，骨矿物质和密度以及其他阶段 BC的派生描述符将扩展。 我们将发展翻译 当我们的方法和验证儿童的替代方法之间的表格 有成年人。 第二个且引人注目的动机来扩展这些 对儿童的研究是为了提高临床护理的质量和 儿科医生及其其的基础研究应用 患者可能会受益。 我们大约2000年完成研究的摘要出版物 志愿成年人和1170年对儿童和青少年的研究 项目将添加旨在为营养人员提供服务， 生理学，儿科，衰老以及其他研究社区 需要身体成分参数。