Integrative Environmental Health Sciences Facility Core

综合环境健康科学设施核心

基本信息

批准号：
10165397
负责人：
CATHERINE J KARR
金额：
$ 16.9万
依托单位：
UNIVERSITY OF WASHINGTON
依托单位国家：
美国
项目类别：
财政年份：
1997
资助国家：
美国
起止时间：
1997-06-01 至 2026-02-28
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10165397
关键词：
Address Area Basic Science Biomedical Research Child Clinical Clinical Research Clinical Sciences Collaborations Collection Communities Consultations Core Facility Disasters Discipline Disease Early Diagnosis Environment Environmental Health Environmental Risk Factor Epigenetic Process Ethics Evolution Fostering Fred Hutchinson Cancer Research Center Funding Funding Opportunities Genetic Genomics Goals Health Health Policy Health Sciences Human Individual Interdisciplinary Study Leadership Methods National Institute of Environmental Health Sciences Occupational Health Patients Physiological Population Study Predisposition Prevention Public Health Public Health Schools Research Research Design Research Institute Research Personnel Resources Sampling Science Scientist Services Structure Technology Testing Time Translational Research Universities Washington base catalyst cohesion community center community engaged research community engagement data to knowledge exposed human population gene environment interaction health practice health science research implementation science improved innovation instrumentation member novel organizational structure population based population health programs repository research study response translational study virtual

项目摘要

INTEGRATIVE ENVIRONMENTAL HEALTH SCIENCES FACILITY CORE ABSTRACT The Integrative Environmental Health Sciences Facility Core (IEHS-FC) acts as the navigator for EDGE Center interdisciplinary research. Here, investigators and trainees connect to Center services and a comprehensive consultation resource emphasizing clinical, translational, and population-based studies. The IEHS-FC facilitates Center member research along the translational continuum. Whether the investigator is involved in basic or experimental sciences, clinical studies or observational population-based studies, the IEHS-FC offers high quality advisement, methods, and resources to enhance EHS research, inform public health policy and practice, and impact individual and population health. The IEHS-FC fosters interdisciplinary team science research throughout the University of Washington by integrating basic sciences research with population-based and clinical EHS research to improve early detection and prevention of environmentally related disorders. The Core also helps to identify collaborative opportunities within the greater NIEHS Core Centers program by promoting and connecting researchers to respond to the EHS Core Centers collaborative research funding opportunities. The IEHS-FC is re-structured with two focus areas in addition to the navigator function. The clinical, translational, and population-based studies focus area remains. Investigators will continue to benefit from services covering study design and execution, clinical and physiological testing, collection and storage of human samples, access to controlled-human exposure facilities, and identifying patient groups and sample repositories. In this renewal, new resources are added to support translational research to address emerging needs in Disaster Research Response (DR2), an emerging focus of the Center. This second focus area supports investigators in the conduct of rigorous, timely, ethical, and safe environmental health disaster research response. The IEHS-FC is the gateway for EDGE Center investigators, fostering interdisciplinary and novel EHS research. Its emphasis on clinical and translational sciences, individual susceptibility factors, and gene-environment interactions are in keeping with the goals of NIEHS to maximize the utilization of human population-based studies in EHS research. By offering expert consultation, research services and appropriate referrals to EDGE Center investigators, the IEHS-FC enhances the interconnectedness of the EDGE Center Facility Cores, the Community Engagement Core (CEC), and other EDGE Center components. By leveraging the outstanding resources of the EDGE Center, the Department of Environmental & Occupational Health Sciences, the School of Public Health and the broader UW biomedical research community, the IEHS-FC provides an important and valued hub for NIEHS funded investigators at the UW, the Fred Hutchinson Cancer Research Center, Seattle Children’s Research Institute, the Center’s community partners, and the local, regional, and national EHS research community.

综合环境健康科学设施核心抽象的综合环境健康科学设施核心 (IEHS-FC) 充当 EDGE 的导航器中心跨学科研究。在这里，研究人员和受训者连接到中心服务和一个中心。全面的咨询资源，强调临床、转化和基于人群的研究。 IEHS-FC 促进中心成员沿着转化连续体进行研究，无论研究者是不是。涉及基础或实验科学、临床研究或基于人群的观察性研究， IEHS-FC 提供高质量的建议、方法和资源，以加强 EHS 研究、告知公众卫生政策和实践，并影响个人和人口健康。整个华盛顿大学的跨学科团队科学研究通过整合基础知识科学研究与基于人群和临床的 EHS 研究相结合，以改善早期发现和预防该核心还有助于识别环境相关疾病的合作机会。通过促进和连接研究人员响应 EHS 核心，扩大 NIEHS 核心中心计划中心合作研究资助机会。除了导航功能外，IEHS-FC 还进行了重组，增加了两个重点区域。转化和基于人群的研究重点领域仍然是研究人员将继续受益的领域。服务涵盖研究设计和执行、临床和生理测试、收集和存储人体样本、进入受控人体暴露设施以及识别患者群体和样本在这次更新中，添加了新的资源来支持转化研究，以解决新兴问题。灾害研究响应（DR2）的需求，这是该中心的第二个重点领域。支持调查人员进行严格、及时、道德和安全的环境健康灾难 IEHS-FC 是 EDGE 中心研究人员的门户，促进跨学科和研究响应。新颖的 EHS 研究。其重点是临床和转化科学、个人易感因素和基因与环境的相互作用符合 NIEHS 的目标，即最大限度地利用人类 EHS 研究中基于人群的研究通过提供专家咨询、研究服务和适当的方法。转介给 EDGE 中心研究人员后，IEHS-FC 增强了 EDGE 的互连性中心设施核心、社区参与核心 (CEC) 和其他 EDGE 中心组件。通过利用EDGE中心的优秀资源，环境与环境部职业健康科学、公共卫生学院和更广泛的华盛顿大学生物医学研究社区，IEHS-FC 为华盛顿大学 NIEHS 资助的研究人员提供了一个重要且有价值的中心，弗雷德·哈钦森癌症研究中心、西雅图儿童研究所、该中心的社区合作伙伴以及当地、区域和国家 EHS 研究社区。