A novel Rhamnosidase: immobilised for repeated biocatalysis use to produce high value chemicals

一种新型鼠李糖苷酶：固定化用于重复生物催化生产高价值化学品

基本信息

批准号：
104611
负责人：
金额：
$ 75.65万
依托单位：
UNILEVER U.K. CENTRAL RESOURCES LIMITED
依托单位国家：
英国
项目类别：
Collaborative R&D
财政年份：
2019
资助国家：
英国
起止时间：
2019 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=104611
关键词：
novel Rhamnosidase immobilised repeated biocatalysis

项目摘要

"Bio-inspired processes will have a major impact on the challenges of the global society in 21st century, including those associated with environmental sustainability. The employment of biocatalysts in industrial processes is expected to boost a sustainable production of chemicals, materials and fuels from renewable resources. The scope of this proposal is to encourage and translate academic research and its outcome into a novel industrially usable platform technology for the sustainable production of commercial high value materials.Rhamnolipids (RL) are biosurfactants from the glycolipid family produced by certain microorganisms (Kiran et al. 2016\*) that could address the growing consumer demand for environmentally friendly, sustainably produced ingredients in everyday products. RL are chemical compounds composed of lipid and sugar moieties containing one (mono-RL) or two (di-RL) molecules of Rhamnose. Di-RL, Mono-RL and Rhamnose all have potential for broader commercial applications (Rhamnose in the flavour/food industry & Skincare, RLs in Skincare, Fabric/Surface Cleaning and Pharmaceuticals). This project will address key challenges in the process of the biocatalytic conversion of RL species, and will therefore be a key enabler for a scalable supply of diverse products to the market.\* Kiran at al. (2016) Rhamnolipids Biosurfactants: evolutionary implications, applications and future prospects from untapped marine resource. Crit Rev Biotechnol., 36(3): 399-415"

“仿生工艺将对 21 世纪全球社会的挑战产生重大影响，包括与环境可持续性相关的挑战。在工业过程中使用生物催化剂预计将促进利用可再生能源可持续生产化学品、材料和燃料。该提案的范围是鼓励学术研究及其成果并将其转化为一种新颖的工业可用平台技术，用于可持续生产商业高价值材料。鼠李糖脂（RL）是来自糖脂家族的生物表面活性剂。某些微生物（Kiran 等人，2016\*）可以满足消费者对日常产品中环保、可持续生产成分日益增长的需求，RL 是由含有一个（单 RL）或两个（单 RL）的脂质和糖部分组成的化合物。 di-RL) 鼠李糖分子，Di-RL、Mono-RL 和鼠李糖都具有更广泛的商业应用潜力（鼠李糖在香料/食品工业和护肤品中，RL 在护肤品中，织物/表面清洁和药品）。该项目将解决 RL 物种生物催化转化过程中的关键挑战，因此将成为向市场扩大多样化产品供应的关键推动者。* Kiran 等人。 (2016) 鼠李糖脂生物表面活性剂：未开发海洋资源的进化意义、应用和未来前景。临界评论生物技术，36（3）：399-415”