Synthesis and evaluation of BSH-containing kojic acid (KA-BSH) as a novel agent for boron neutron capture therapy
含 BSH 的曲酸(KA-BSH)的合成和评价作为硼中子俘获疗法的新型药物
基本信息
- 批准号:26462192
- 负责人:
- 金额:$ 3.16万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2014
- 资助国家:日本
- 起止时间:2014-04-01 至 2017-03-31
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The Anti-Proliferative Effect of Boron Neutron Capture Therapy in Prostate Cancer Xenograft Model
硼中子捕获疗法在前列腺癌异种移植模型中的抗增殖作用
- DOI:10.1371/journal.pone.0136981
- 发表时间:2015
- 期刊:
- 影响因子:3.7
- 作者:Takahara K; Inamoto T; Minami K; Yoshikawa Y; Takai T; Ibuki N; Hirano H; Nomi H; Kawabata S; Kiyama S; Miyatake S; Kuroiwa T; Suzuki M; Kirihata M; Azuma H.
- 通讯作者:Azuma H.
Evaluation of BSH containing Kojic acid (KA-BSH) as novel agents for boron neutron capture therapy
含有曲酸的 BSH(KA-BSH)作为硼中子俘获疗法新型药物的评价
- DOI:
- 发表时间:2016
- 期刊:
- 影响因子:0
- 作者:Takeuchi K; Kawabata S; Futamura G; Hiramatsu R; Kuroiwa T; Hattori Y; Kirihata M; Tanaka H; Sakurai Y; Masunaga S; Ono K; Miyatake SI
- 通讯作者:Miyatake SI
Inflammation as well as angiogenesis may participate in the pathophysiology of brain radiation necrosis.
炎症和血管生成可能参与脑放射性坏死的病理生理学。
- DOI:10.1093/jrr/rru017
- 发表时间:2014
- 期刊:
- 影响因子:2
- 作者:Yoritsune E; Furuse M; Kuwabara H; Miyata T; Nonoguchi N; Kawabata S; Hana Hayasaki H; Kuroiwa T; Ono K; Shibayama Y;Miyatake S
- 通讯作者:Miyatake S
ホウ素中性子捕捉療法(BNCT)による再発悪性神経膠腫の治療~現状と展望
硼中子俘获疗法(BNCT)治疗复发性恶性胶质瘤——现状与前景
- DOI:
- 发表时间:2015
- 期刊:
- 影响因子:0
- 作者:川端信司;宮武伸一;竹内孝治;平松 亮;松下葉子;野々口直助;古瀬元雅;鈴木 実;小野公二;黒岩敏彦
- 通讯作者:黒岩敏彦
Delayed brain radiation necrosis: pathological review and new molecular targets for treatment.
迟发性脑放射性坏死:病理学检查和新的分子治疗靶点。
- DOI:
- 发表时间:2015
- 期刊:
- 影响因子:0
- 作者:Furuse M; Nonoguchi N; Kawabata S; Miyatake S; Kuroiwa T
- 通讯作者:Kuroiwa T
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Kawabata Shinji其他文献
Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model
多靶点中子捕获疗法与 18 kDa 易位蛋白靶向硼化合物相结合是大鼠脑肿瘤模型中的有效策略
- DOI:
10.3390/cancers15041034 - 发表时间:
2023 - 期刊:
- 影响因子:5.2
- 作者:
Kashiwagi Hideki;Hattori Yoshihide;Kawabata Shinji;Kayama Ryo;Yoshimura Kohei;Fukuo Yusuke;Kanemitsu Takuya;Shiba Hiroyuki;Hiramatsu Ryo;Takami Toshihiro;Takata Takushi;Tanaka Hiroki;Watanabe Tsubasa;Suzuki Minoru;Hu Naonori;Miyatake Shin;Kirihata Mi - 通讯作者:
Kirihata Mi
Multi-Targeted Neutron Capture Therapy Combined with an 18 kDa Translocator Protein-Targeted Boron Compound Is an Effective Strategy in a Rat Brain Tumor Model
多靶点中子捕获疗法与 18 kDa 易位蛋白靶向硼化合物相结合是大鼠脑肿瘤模型中的有效策略
- DOI:
10.3390/cancers15041034 - 发表时间:
2023 - 期刊:
- 影响因子:5.2
- 作者:
Kashiwagi Hideki;Hattori Yoshihide;Kawabata Shinji;Kayama Ryo;Yoshimura Kohei;Fukuo Yusuke;Kanemitsu Takuya;Shiba Hiroyuki;Hiramatsu Ryo;Takami Toshihiro;Takata Takushi;Tanaka Hiroki;Watanabe Tsubasa;Suzuki Minoru;Hu Naonori;Miyatake Shin;Kirihata Mi - 通讯作者:
Kirihata Mi
Dodecaborate Conjugates Targeting Tumor Cell Overexpressing Translocator Protein for Boron Neutron Capture Therapy
十二硼酸盐缀合物靶向肿瘤细胞过表达易位蛋白,用于硼中子捕获疗法
- DOI:
10.1021/acsmedchemlett.1c00377 - 发表时间:
2021 - 期刊:
- 影响因子:4.2
- 作者:
Hattori Yoshihide;Ishimura Miki;Ohta Youichirou;Takenaka Hiroshi;Kawabata Shinji;Kirihata Mitsunori - 通讯作者:
Kirihata Mitsunori
Evaluation of the energy resolution of a prompt gamma-ray imaging detector using LaBr3(Ce) scintillator and 8 × 8 array MPPC for an animal study of BNCT
使用 LaBr3(Ce) 闪烁体和 8 × 8 阵列 MPPC 评估瞬发伽马射线成像探测器的能量分辨率,用于 BNCT 动物研究
- DOI:
10.1016/j.apradiso.2020.109214 - 发表时间:
2020 - 期刊:
- 影响因子:1.6
- 作者:
Okazaki Keita;Tanaka Hiroki;Takata Takushi;Kawabata Shinji;Akabori Kiyotaka;Sakurai Yoshinori - 通讯作者:
Sakurai Yoshinori
The Therapeutic Effects of Dodecaborate Containing Boronophenylalanine for Boron Neutron Capture Therapy in a Rat Brain Tumor Model
含硼苯丙氨酸的十二硼酸盐用于硼中子俘获疗法对大鼠脑肿瘤模型的治疗作用
- DOI:
10.3390/biology9120437 - 发表时间:
2020 - 期刊:
- 影响因子:4.2
- 作者:
Fukuo Yusuke;Hattori Yoshihide;Kawabata Shinji;Kashiwagi Hideki;Kanemitsu Takuya;Takeuchi Koji;Futamura Gen;Hiramatsu Ryo;Watanabe Tsubasa;Hu Naonori;Takata Takushi;Tanaka Hiroki;Suzuki Minoru;Miyatake Shin;Kirihata Mitsunori;Wanibuchi Masahiko - 通讯作者:
Wanibuchi Masahiko
Kawabata Shinji的其他文献
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{{ truncateString('Kawabata Shinji', 18)}}的其他基金
Establishment of multi-target neutron capture therapy with multiple boron drugs for brain tumor
多种硼药物多靶点中子俘获治疗脑肿瘤的建立
- 批准号:
20H03797 - 财政年份:2020
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Translocator protein (TSPO) targetting boron deliverly and neutron capture therapy against malignant brain tumors
易位蛋白(TSPO)靶向硼输送和中子捕获治疗恶性脑肿瘤
- 批准号:
17K10878 - 财政年份:2017
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
相似海外基金
Development and Validation of Safe and Efficient Multi-functional Boron Nanoformulation for Next-generation BNCT
用于下一代 BNCT 的安全高效多功能硼纳米制剂的开发和验证
- 批准号:
18K07256 - 财政年份:2018
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Clinical comparison of nuclear reactor BNCT and accelerator BNCT for head and neck cancer.
核反应堆BNCT与加速器BNCT治疗头颈癌的临床比较。
- 批准号:
24592611 - 财政年份:2012
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Therapeutic effect improvement by new boron neutron capture therapy with amino acid - BSH
新型氨基酸硼中子俘获疗法改善疗效 - BSH
- 批准号:
23592146 - 财政年份:2011
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Improvement of BNCT effect by control of intracellular distribution
通过控制细胞内分布提高BNCT效果
- 批准号:
23500544 - 财政年份:2011
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of boron-conjugate targeting adenovirus vector for novel boron neutron capture therapy
开发用于新型硼中子捕获疗法的硼缀合物靶向腺病毒载体
- 批准号:
23592126 - 财政年份:2011
- 资助金额:
$ 3.16万 - 项目类别:
Grant-in-Aid for Scientific Research (C)