Early-Stage Medical Diagnostics by Plasmon-Mediated Gas Sensing

通过等离子体介导的气体传感进行早期医学诊断

• 批准号: DP150101939
• 负责人: Prof Antonio Tricoli
• 金额: $ 29.94万
• 依托单位: The Australian National University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-06-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP150101939
• 关键词: Early; Stage; Medical; Diagnostics; Plasmon

This project will investigate the use plasmonic absorption of light in metal nanostructures to activate the selective oxidation/reduction of a gas molecule on a semiconductor nanoparticle. This concept will be used with the aim of developing a sensing technique capable of measuring ultra-low concentrations (ppb) of breath markers for lung cancer detection. It is expected that porous sensing films of semiconductor and metal nanoparticles with well-defined light absorption properties will be fabricated. Superior selectivity will be achieved by matching the wavelength of the absorbed light with the required activation energy for oxidation/reduction. Successful outcomes will enable multi-analyte fingerprint identification by on-chip devices with applications ranging from portable medical diagnostics to national security.

该项目将研究利用金属纳米结构中的等离激元吸收光来激活半导体纳米颗粒上气体分子的选择性氧化/还原。这一概念的目的是开发一种能够测量超低浓度 (ppb) 呼吸标记物的传感技术，用于肺癌检测。预计将制造出具有明确光吸收特性的半导体和金属纳米粒子的多孔传感薄膜。通过将吸收光的波长与氧化/还原所需的活化能相匹配，可以实现优异的选择性。成功的成果将使片上设备能够进行多分析物指纹识别，其应用范围从便携式医疗诊断到国家安全。