Yellow Gold: Innovative systems for sustainable daffodil-derived galanthamine production in the uplands.

黄金：在高地可持续生产水仙花加兰他敏的创新系统。

• 批准号: 102123
• 金额: $ 51.24万
• 依托单位: AGROCEUTICAL PRODUCTS LTD
• 依托单位国家: 英国
• 项目类别: BEIS-Funded Programmes
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=102123
• 关键词: Yellow; Gold; Innovative; systems; sustainable

Galantamine is a pharmaceutical product that had been an approved Alzheimer’s Disease treatment since 1998. Galantamine can be synthesised chemically but it is a difficult and expensive process. Producing galantamine from galanthamine extracted from plants is more cost effective, but supplies are limited. Daffodils are an economically feasible plant source for cultivation in the UK, and growing daffodils in upland areas triggers a 50% higher yield of galanthamine. This proposal will deliver a new approach for producing galanthamine based on integrating daffodil growing into existing upland pasture. This will increase the economic sustainability of hill farming by providing farmers with a high value crop while maintaining traditional farming systems in the upland areas. The project will develop the required machinery, quantify the yield of galanthamine achievable, and assess the impact on sheep performance of incorporating daffodil production into grazed pastures.

加兰他敏是一种药品，自 1998 年起就被批准用于治疗阿尔茨海默病。加兰他敏可以通过化学合成，但这是一个困难且昂贵的过程。从植物中提取的加兰他敏生产加兰他敏更具成本效益，但水仙花的供应有限。在英国种植水仙花在经济上是可行的，在高地地区种植水仙花可使加兰他敏的产量提高 50%。该提案将提供一种新的生产方法。加兰他敏将水仙花种植融入现有的高地牧场，这将为农民提供高价值作物，同时维持高地地区的传统农业系统，从而提高山地农业的经济可持续性。加兰他敏可实现的目标，并评估将水仙花生产纳入放牧牧场对绵羊生产性能的影响。