The Effect of Antenatal Maternal Cannabis Use on Parenting Behavior

产前吸食大麻对育儿行为的影响

基本信息

批准号：
10594488
负责人：
Natasha Alessandra Sokol
金额：
$ 18.06万
依托单位：
MIRIAM HOSPITAL
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-04-01 至 2027-03-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10594488
关键词：
Acute Address Adult Area Award Behavior Behavioral Biological Biological Assay Biological Markers Cannabis Cannabis policy Child Child Health Child Rearing Chronic stress Clinical Research Cognitive Complex Data Analyses Data Collection Development Developmental Process Discrimination Disparity Drug Addiction Drug usage Education Emotional Environment Environmental Risk Factor Epidemiologic Methods Family Frequencies Goals Growth Harm Reduction Health Health behavior Hormones Human Subject Research Hydrocortisone Income Individual Inequity Infant Intervention Interview Laboratories Legal Life Cycle Stages Life course epidemiology Longevity Longitudinal cohort Marijuana Dependence Maternal and Child Health Measurement Measures Mediating Mental Health Mentored Research Scientist Development Award Methods Mothers Motivation National Institute of Drug Abuse Outcome Parents Pathway interactions Pharmaceutical Preparations Physiological Play Population Postpartum Period Pregnancy Pregnant Women Prevalence Qualitative Methods Race Reporting Research Research Personnel Risk Role Social Environment Social Policies Societies Statistical Methods Strategic Planning Stress Stress and Coping Surveys Techniques Theoretical model Training Training Activity United States Woman antenatal behavior observation cannabis administration cannabis use behavior career career development coping mechanism critical period design developmental psychology drug of abuse epidemiological model experience health disparity health inequalities hypothalamic-pituitary-adrenal axis improved insight intergenerational marijuana use marijuana user maternal marijuana use novel offspring outcome disparities peer perceived stress physical conditioning postnatal prospective social social determinants social epidemiology social norm socioeconomics stress management substance use therapy development transmission process

项目摘要

PROJECT SUMMARY As United States cannabis policy shifts toward liberalization, norms and behaviors around adult use have shifted in kind. This includes parent use, which is increasing in frequency and prevalence. While certain deficits have been found in children of parents who use cannabis, these associations are inherently subject to confounding by parents and children’s social environments, and potential for causal inference has been limited. Parents report using for stress-coping, but the relationship between cannabis and stress is complex and highly dependent on social context. Patterns of cannabis use among parents mirror existing health inequities. Theoretical social epidemiologic models suggest that drug use as a stress-coping mechanism is both a reflection of health inequities and cause of health disparities, which may be further exacerbated in the context of intergenerational effects. Theoretical models and empirical evidence from developmental psychology underline the important and interacting roles of substance use, stress and the social environment on parenting. This Mentored Research Scientist Development Award (K01) will support the Candidate’s career development as an independent interdisciplinary researcher in modifiable factors that produce disparities and inequities in substance use, treatment and consequences across the life course. The award will support the Candidate’s short-term goal of understanding the intergenerational transmission of cannabis-related harm. This application aims to contribute a clearer understanding of the complex relationships between diverse families’ social environments, maternal cannabis use, parenting behaviors, and the maternal-infant relationship in the six months postpartum. Specific aims are to 1) understand the impact of maternal cannabis use in the first six months postpartum on parenting behaviors and maternal-infant interaction; 2) understand the influence of discrimination in the relationship between stress, cannabis use and parenting; and 3) characterize motivations for maternal cannabis use through qualitative interviews. Research aims will be explored in a prospective longitudinal cohort of pregnant women who use cannabis, following mothers and infants until one year postpartum. Outcomes will be assessed using qualitative and quantitative techniques, including interviews, surveys, behavioral observation, and biomarker measurement. By focusing on multiple levels of modifiable influence on maternal cannabis use, parenting and the maternal-infant relationship, including behavioral and biological pathways, results from this research have the potential to provide unique opportunities to address maternal and child health in the context of shifting social and legal norms surrounding adult cannabis use. This research is designed to address the Objective 4.1 of NIDA’s strategic plan to determine the impact of drug use and addiction on individuals, families, peers and society. The training plan is designed to prepare the Candidate for a career as an interdisciplinary researcher in substance use by supplementing her background in social epidemiology and secondary data analysis with training in stress research and primary data collection.

项目摘要随着美国大麻政策转向自由化转变为包括父母，车轮在自由和过早的情况下增加。在使用大麻的父母的孩子中发现了这些关联，固有地父母和孩子的社会环境和因果推断的潜力受到限制。父母报告使用压力打击，但大麻与压力之间的关系很复杂且高度依赖社会环境。理论社会流行病学模型模型表明，用作屁股涂抹机制的药物都是卫生不平等和健康差异原因的反映，这可能国际性效应。强调了物质使用，压力和社会环境在育儿中的重要和相互作用的作用。这个指导的研究科学家发展奖（K01）将支持候选人的职业发展是一个扎实的跨学科研究人员，这是导致差异和的因素因素。在整个生命过程中，药物使用，治疗和后果的不平等将支持该奖项。候选人理解与史蒂斯米斯斯相关的危害的短期目标。应用程序旨在更清楚地了解各种家庭之间的复杂关系社交环境，孕产妇使用，陈旧行为以及孕产妇的关系产后六个月。几个月的育儿行为和孕产妇交往； 2）压力，大麻使用和育儿之间的关系；对于孕产妇大麻，使用定性访谈。使用大麻，跟随母亲和婴儿直到一年的孕妇的纵向队列产后将使用定性和定量技术评估结果调查，行为观察和生物标志物测量。对孕产妇使用，育儿和孕产妇的关系的影响，包括行为和生物学途径，研究结果有可能提供独特的机会来解决在改变社会和法律正常正常大麻的情况下，孕产妇和儿童健康研究旨在增加NIDA战略计划的目标4.1，以确定吸毒的影响对个人，家庭，同伴和社会的成瘾旨在为您做好准备候选人从事支持我们的属性研究人员的候选人？社会流行病学和二级数据分析，包括压力研究和主要数据收集的培训。