Temple Strategies to Innovate EmeRgENcy Care Clinical Trials Network (Temple-SIREN)

Temple 创新紧急护理临床试验网络的策略 (Temple-SIREN)

基本信息

批准号：
10552436
负责人：
NINA T GENTILE
金额：
$ 40.91万
依托单位：
TEMPLE UNIV OF THE COMMONWEALTH
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-15 至 2028-01-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10552436
关键词：
Academic Medical Centers Accident and Emergency department Acute Address Adenovirus Vector Adherence Adult African American Agreement Area Award Baltimore COVID-19 COVID-19 pandemic COVID-19 prevention Cardiac Cardiopulmonary Cessation of life Child Childhood Cities Clinical Clinical Research Clinical Trials Clinical Trials Network Collaborations Communication Communities Country County Data Coordinating Center Delaware Discipline Education Emergency Care Emergency Medicine Emergency Situation Emergency research Emotional Enrollment Ethnic Origin Evaluation Faculty Fellowship Financial cost Fostering Funding Future Geographic Locations Grant Health Policy Health Services Health system Hispanic Populations Hospital Departments Hospitals Informatics Injury Institution Language Leadership Lung Maryland Medicine Minority Groups Neurologic Neurology New Jersey New York Nursing Services Outcome Patient Care Patients Pennsylvania Persons Philadelphia Population Heterogeneity Pre-hospital setting Process Productivity Protocols documentation Provider Race Research Research Design Research Infrastructure Research Personnel Research Support Rewards Role Route Shock Site Societies Socioeconomic Status Structure System Time Training Translating Trauma Traumatic Brain Injury United States National Institutes of Health Universities University Hospitals Work acute care clinical practice disability improved injured innovation meetings member minority patient multidisciplinary operation participant enrollment payment pre-clinical research and development rural area social suburb surveillance study symposium synergism trauma centers trial enrollment vaccine trial webinar working group

项目摘要

The Temple-led Emergency care research network (Temple-SIREN) is comprised of multiple community and academic medical centers and EMS providers throughout Philadelphia, New Jersey, Delaware, and Maryland to execute SIREN emergency care trials. To meet the needs for specific study enrollment, Temple-SIREN engaged the highest volume emergency and trauma centers and the busiest EMS systems in the region. This large hub-spoke network serves very diverse populations in densely populated cities as well as highly affluent suburban areas to rural regions of Bucks and Berks counties in PA Dutch country. Temple-SIREN Hub and spoke leaders are committed to emergency care research and are active in trials of acute cardiopulmonary and neurological illness and traumatic brain injury trials. Through collaboration and hub oversight, the Temple-SIREN group expects to significantly contribute SIREN studies' enrollment. In addition, we plan to stay ahead of the curve by translating preclinical work to the bedside and using our highly diverse regional network for studies that needs of our diverse communities. The Temple-SIREN Hub staff will work closely with participating site investigators and coordinators from multiple disciplines to efficiently execute SIREN studies. Mechanisms to enhance efficiency and quality of clinical research across sites include use of a common informatics system to identify potential study patients; frequent communication with investigators and coordinators via webinars and conference calls; diligent site management focused on good clinical research practices and compliance, and regular Hub-spoke meetings to provide additional training by study role. Temple-SIREN investigators and coordinators will participate in SIREN clinical coordinating center and data management center and ad hoc working groups to develop SIREN studies. The Temple-SIREN Hub team would benefit from participating in this coordinated approach to emergency care research as would the people of Philadelphia and the surrounding communities served by our hospitals and EMS systems.

由寺庙领导的紧急护理研究网络（Temple-Siren）由费城，新泽西州，特拉华州和马里兰州的多个社区和学术医疗中心以及EMS提供商组成，以执行Siren紧急护理试验。为了满足特定研究入学的需求，Temple-Siren与该地区最繁忙的EMS系统接触了最高的紧急情况和创伤中心。这个大型的枢纽网络在人口稠密的城市以及荷兰国家雄鹿和伯克斯县的农村地区非常富裕的郊区提供非常多样化的人口。 Temple-Siren枢纽和讲话领导者致力于急诊研究，并积极参加急性心肺和神经系统疾病以及创伤性脑损伤试验的试验。通过协作和枢纽的监督，Temple-Siren集团预计将显着贡献Siren研究的入学率。此外，我们计划通过将临床前工作转换为床边，并使用我们高度多样化的区域网络来保持曲线的领先地位，以进行我们不同社区的研究。 Temple-Siren Hub的工作人员将与参与的现场调查员和协调员紧密合作，从多个学科到有效执行警笛研究。提高跨站点临床研究效率和质量的机制包括使用通用信息系统来识别潜在的研究患者；经常通过网络研讨会和电话会议与调查人员和协调员进行沟通；勤奋的站点管理着重于良好的临床研究实践和合规性，并定期进行枢纽会议，以通过研究角色提供额外的培训。 Temple-Siren的调查人员和协调员将参加Siren临床协调中心，数据管理中心以及临时工作组，以开发警笛研究。 Temple-Siren枢纽团队将受益于参与这种协调的急诊研究方法，费城人民和周围社区的医院和EMS系统也会受益。