Southwest Health Equity Research Collaborative (SHERC)

西南健康公平研究合作组织 (SHERC)

基本信息

批准号：
10555410
负责人：
Julie Ann Baldwin
金额：
$ 447.4万
依托单位：
NORTHERN ARIZONA UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-09-20 至 2027-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10555410
关键词：
2019-nCoV Accountability Address Affect Area Arizona Asthma Behavior Therapy Behavioral Research Behavioral Sciences Biomedical Research Biometry Childhood Asthma Chronic Disease Clinical Clinical Research Clinical Sciences Clinical and Translational Science Awards Collaborations Communicable Diseases Communities Computing Methodologies County Data Analyses Data Collection Data Science Data Security Development Disease Ensure Environment Evaluation Extramural Activities Federally Qualified Health Center Feedback Fiber Fostering Funding Geography Goals Health Hospitals Imprisonment Individual Informatics Infrastructure Institution Intervention Justice Laboratories Lead Logistics Mentors Methodology Methods Minority-Serving Institution Modeling Morbidity - disease rate Outcome Physical activity Pilot Projects Policies Population Population Heterogeneity Postdoctoral Fellow Productivity Program Development Quality Control Reduce health disparities Relationship-Building Research Research Design Research Personnel Research Project Grants Risk Role Schools Science Scientific Inquiry Southwestern United States Supplementation Testing Time Translational Research Underserved Population United States Indian Health Service United States National Institutes of Health Universities Woman Work airway inflammation authority base behavioral health career community engagement data quality design disease transmission diversity and equity efficacious intervention empowered epidemiological model evidence base gut microbiome health disparity health disparity populations health equity health goals health inequalities improved innovation laboratory equipment leadership development member mortality novel population health programs recruit reduce symptoms research facility resilience respiratory microbiome sedentary lifestyle senior faculty social health determinants theories tool tribal health

项目摘要

PROJECT SUMMARY The overall goal of the Southwest Health Equity Research Collaborative (SHERC) is to increase basic biomedical, clinical, and behavioral research at Northern Arizona University (NAU) to address health disparities and advance health equity among diverse populations of the southwestern United States. In the next 5 years, we will increase research capacity especially in the areas of clinical and translational research with a focus on team science and diversity, equity, inclusion, and justice (DEIJ). SHERC will work closely with community partners to expand capacity to address health disparities in multiple chronic and infectious diseases, as well as high-priority behavioral health conditions, as determined by community partners. SHERC consists of 5 cores that all interact synergistically. Each of the SHERC cores provides a clear opportunity for innovation individually; in combination, they demonstrate significant impact in innovation. The Administrative Core combines evidence-based organizational theory with a tested but novel use of a “continuous improvement” model of program assessment and feedback. The innovative Core Leadership Development Program will cultivate a new cadre of mentored research leaders from underrepresented (UR) backgrounds. The Research Capacity Core focuses on enhancing translational, data, and clinical science, and simultaneously aims to grow the use of novel laboratory technologies, cutting-edge community-engaged methods and models, biostatistics, interinstitutional collaborations, and support of relevant NAU core research facilities. The Investigator Development Core will support early-stage investigators in basic biomedical, behavioral, and clinical sciences at NAU through 2 programs: a Pilot Project Program and an Individualized Mentoring Program. The Community Engagement Core uses an innovative 4-direction Framework for Inquiry and Action that will represent the shared and distinct social determinants of health in Arizona. The Recruitment Core aims to recruit 2 mid-level or senior faculty members with established health equity research programs to fill gaps in institutional expertise; to support the new hires in establishing collaborative and independent health equity research programs at NAU; and to integrate them into SHERC as collaborators, mentors, and leaders. The 3 Research Projects include the following innovative studies: Project 1 (Camplain) addresses physical activity and sedentary behavior and their impact on health outcomes among women incarcerated in Arizona. Project 2 (Cope) focuses on childhood asthma and aims to determine the effect of a gut microbiome modifying therapy (fiber supplementation) to improve type-2 asthma symptoms by reducing airway inflammation via the gut microbiome-airway axis. Project 3 (Mihaljevic) will develop and operationalize modeling tools that allow us to rapidly improve the design and implementation of spatial epidemiological models of SARS-CoV-2 that are informed by local-level geographic and demographic features, including social determinants of health.

项目摘要西南健康公平研究合作（SHERC）的总体目标是增加基本北亚利桑那大学（NAU）的生物医学，临床和行为研究以解决健康分布并促进美国西南部潜水员人口的健康公平。在接下来的5年中，我们将提高研究能力，尤其是在临床和翻译研究领域，重点团队科学与多样性，公平，包容和正义（DEIJ）。 Sherc将与社区紧密合作合作伙伴扩大能力解决多种慢性和传染病的健康分配的能力，以及由社区伙伴确定的高优先级行为健康状况。 Sherc由5个核心组成所有这些都协同互动。每个Sherc核心为创新提供了明显的机会单独；结合起来，它们对创新表现出重大影响。行政核心将基于证据的组织理论与经过测试但新颖的“持续改进”相结合计划评估和反馈的模型。创新的核心领导力发展计划将培养来自代表性不足（UR）背景的新的受过指导研究领导者干部。研究能力核心专注于增强翻译，数据和临床科学，而只是旨在扩大新型实验室技术，尖端社区参与方法和模型的使用，生物统计学，机构间合作以及相关NAU核心研究设施的支持。这研究者开发核心将支持基本生物医学，行为和 NAU通过2个计划的临床科学：试点项目计划和个性化指导程序。社区参与核心使用创新的4方向框架进行查询和将代表亚利桑那州卫生的共同社会决定者的行动。招募核心目标是招募2名中级或高级教职员工，并拥有既定的健康公平研究计划填补机构专业知识的空白；支持新员工建立合作和独立健康 NAU的股权研究计划；并将它们整合到Sherc中，成为合作者，导师和领导者。这三个研究项目包括以下创新研究：项目1（camplain）解决了身体活动和久坐行为及其对亚利桑那州受影响妇女的健康结果的影响。项目2（COPE）着重于儿童哮喘，旨在确定肠道微生物组的影响通过通过减少气道注射来改善2型哮喘症状的治疗（补充纤维）肠道微生物组轴。项目3（Mihaljevic）将开发和操作允许我们的建模工具快速改善SARS-COV-2的空间流行病学模型的设计和实施由地方级地理和人口特征（包括健康的社会决定者）所告知。