An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes

通过行为助推进行家庭检测的适应性干预试验，以改善糖尿病患者的 COVID-19 检测和预防

• 批准号: 10548235
• 负责人: Kabayam M Venkat Narayan
• 金额: $ 99万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-07 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10548235
• 关键词: Adherence; Adoption; Adult; Affect; African American; Age; Appointment; Attitude; Behavior; Behavioral; Black race; COVID-19; COVID-19 mortality; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 test; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Caring; Cellular Phone; Climate; Clinic; Collaborations; Collection; Communities; Community Health; County; Data; Data Collection; Death Rate; Diabetes Mellitus; Diagnostic Reagent Kits; Disadvantaged; Epidemiology; Equity; Ethnic Origin; Face; Faith; Family member; Funding; Health; Health behavior; Home; Hospitals; Household and Family; Individual; Institution; Intervention Studies; Intervention Trial; Interview; Knowledge; Latinx; Learning; Long COVID; Methods; Minority; Minority Groups; Modeling; Monitor; Morehouse School of Medicine; Obesity; Participant; Perception; Persons; Phase; Play; Population; Positive Reinforcements; Prediabetes syndrome; Preventive; RADx Underserved Populations; Race; Randomized; Recording of previous events; Reporting; Research; Research Personnel; Resistance; Risk; Role; SARS-CoV-2 infection; Schedule; Site; Social Distance; Suggestion; Surveys; System; Technology; Test Result; Testing; Text; Text Messaging; Translational Research; Universities; Vaccination; Vaccines; Vulnerable Populations; adaptive intervention; barrier to testing; behavior change; community organizations; community partnership; design; diabetes risk; disorder prevention; follow-up; high risk; high risk population; home test; improved; informant; interest; member; news; pandemic disease; pandemic response; programs; recruit; sex; social; social media; social stigma; socioeconomics; study population; testing uptake; uptake; vaccine acceptance; vaccine distribution; vaccine hesitancy; vulnerable community; Adherence; Adoption; Adult; Affect; African American; Age; Appointment; Attitude; Behavior; Behavioral; Black race; COVID-19; COVID-19 mortality; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 test; COVID-19 testing; COVID-19 vaccination; COVID-19 vaccine; Caring; Cellular Phone; Climate; Clinic; Collaborations; Collection; Communities; Community Health; County; Data; Data Collection; Death Rate; Diabetes Mellitus; Diagnostic Reagent Kits; Disadvantaged; Epidemiology; Equity; Ethnic Origin; Face; Faith; Family member; Funding; Health; Health behavior; Home; Hospitals; Household and Family; Individual; Institution; Intervention Studies; Intervention Trial; Interview; Knowledge; Latinx; Learning; Long COVID; Methods; Minority; Minority Groups; Modeling; Monitor; Morehouse School of Medicine; Obesity; Participant; Perception; Persons; Phase; Play; Population; Positive Reinforcements; Prediabetes syndrome; Preventive; RADx Underserved Populations; Race; Randomized; Recording of previous events; Reporting; Research; Research Personnel; Resistance; Risk; Role; SARS-CoV-2 infection; Schedule; Site; Social Distance; Suggestion; Surveys; System; Technology; Test Result; Testing; Text; Text Messaging; Translational Research; Universities; Vaccination; Vaccines; Vulnerable Populations; adaptive intervention; barrier to testing; behavior change; community organizations; community partnership; design; diabetes risk; disorder prevention; follow-up; high risk; high risk population; home test; improved; informant; interest; member; news; pandemic disease; pandemic response; programs; recruit; sex; social; social media; social stigma; socioeconomics; study population; testing uptake; uptake; vaccine acceptance; vaccine distribution; vaccine hesitancy; vulnerable community

ABSTRACT This multi-institution team (Emory University, Morehouse School of Medicine, Georgia Institute of Technology), anchored by the Georgia Center for Diabetes Translation Research (P30DK111024) partnership, proposes to leverage and expand on the on-going, RADx-UP funded Project PEACH (P30DK111024), to design and evaluate a home-based COVID-19 testing program with behavioral nudges delivered via mobile phone texts to increase uptake of COVID-19 prevention activities (testing, vaccination, preventive behaviors) in “An Adaptive Intervention Trial of Home Testing with Behavioral Nudges for Improving COVID-19 Testing and Prevention among People Affected by Diabetes.” COVID-19 testing remains a cornerstone in understanding and managing the COVID-19 pandemic. The state of Georgia faces several challenges to COVID-19 management including low vaccine rates, over-extended community health partners struggling to manage both COVID-19 testing and vaccination, decreasing COVID-19 testing numbers, and large populations at elevated risk, including those with or at risk for diabetes, individuals at lower socioeconomic levels, and African American/Black and LatinX communities. In Project PEACH2, we propose to leverage the community partnerships developed and expanded at part of Project PEACH to gather additional information on COVID-19 testing, with a particular focus on at-home testing solutions (Aim 1), using both quantitative (an expansion of the follow-up surveys already being conducted as part of Project PEACH) and qualitative (in-depth interviews with 100 community members, key stakeholders, and community partners) methods. This data, along with the findings of Project PEACH and Georgia CEAL (1OT2HL156812-01/16-312-0217571-66105L), will be used to develop text message, behavioral nudges to promote continued COVID-19 testing, reporting and preventive behaviors including vaccination targeted to participants’ race/ethnicity, sex, age, vaccination status, and testing history. We will then evaluate (Aim 2a) the uptake, usage, and views of a home testing platform (provision a single home COVID-19 test kit for each household family member, collection of test results via an online reporting system, and targeted behavioral nudges delivered via text messages) in a randomized community- based, adaptive intervention trial (n=600) targeting individuals affected by diabetes through collaborations with community partner sites (faith- and community-based organization, the Grady Diabetes Clinic, COVID-19 community testing and vaccine distribution sites). We will also assess (Aim 2b) how the home testing platform affects vaccine uptake and hesitancy among study participants and family members. This study will build on the successful community-academic partnerships created through Project PEACH to further promote COVID- 19 testing among the most vulnerable communities in Georgia. Lessons learned can be disseminated to other at-risk communities and can be adapted to promote home-based testing for other conditions.

抽象的 这个多机构团队（埃默里大学，莫里豪斯医学院，佐治亚理工学院）， 由佐治亚州糖尿病翻译研究中心（P30DK111024）锚定，提案 利用和扩展正在进行的RADX-UP资助项目（P30DK111024），以设计和设计 评估一个基于家庭的COVID-19测试计划，并通过手机提供的行为推动 增加了COVID-19预防活动的摄取（测试，疫苗接种，预防行为）的文本 与行为午睡的家庭测试的自适应干预试验，用于改进COVID-19测试 以及受糖尿病影响的人们的预防。 理解和管理COVID-19的大流行。佐治亚州面临一些挑战 COVID-19的管理层包括低疫苗率，过度扩张的社区健康合作伙伴挣扎 同时管理Covid-19测试和疫苗接种，减少COVID-19测试数字和大量人群 处于较高的风险，包括患有糖尿病风险或有风险的人，社会经济水平较低的人以及 非裔美国人/黑人和拉丁文社区。在Peach2项目中，我们建议利用社区 在Peach项目的一部分中建立和扩展的合作伙伴关系，以收集有关Covid-19的其他信息 测试，特别关注在家测试解决方案（AIM 1），使用既有定量（扩展） 后续调查已经作为桃子项目的一部分进行）和定性（深入的访谈 有100名社区成员，主要利益相关者和社区合作伙伴）方法。这些数据，以及 PECH和GEORGIA CEAL项目的发现（1OT2HL156812-01/16-312-0217571-66105L）将用于 开发短信，行为轻推，以促进持续的COVID-19测试，报告和预防性 行为，包括针对参与者种族/种族，性别，年龄，疫苗状况和测试的疫苗 历史。然后，我们将评估（AIM 2A）家庭测试平台的吸收，用法和视图（提供 每个家庭成员的单个家用Covid-19测试套件，通过在线收集测试结果 报告系统，以及通过文本消息传递的针对性的行为轻推）在一个随机社区中 - 基于与糖尿病影响的个体的基于自适应干预试验（n = 600）通过与 社区合作伙伴网站（基于信仰和社区的组织，Grady糖尿病诊所，Covid-19 社区测试和疫苗分配地点）。我们还将评估（AIM 2B）家庭测试平台如何 影响研究参与者和家人的疫苗摄取和犹豫。这项研究将基于 通过Peach项目建立了成功的社区学术伙伴关系，以进一步促进Covid- 19在佐治亚州最脆弱的社区中进行测试。经验教训可以传播到其他 处于危险的社区，可以改编以促进基于家庭的测试针对其他条件。