ISMRM workshop on MRI of Neuromodulation

ISMRM 神经调节 MRI 研讨会

• 批准号: 10540622
• 负责人: Danny JJ WANG
• 金额: $ 1万
• 依托单位: UNIVERSITY OF SOUTHERN CALIFORNIA
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10540622
• 关键词: Acoustics; Address; Animal Model; Area; BRAIN initiative; Baltimore; Biophysics; Boston; Brain; Brain Diseases; Cognition; Collaborations; Communities; Complex; Deep Brain Stimulation; Development; Devices; District of Columbia; Doctor of Philosophy; Educational workshop; Electromagnetic Fields; Funding; Gender; Goals; Human; Image; Imaging Techniques; Implant; Industry; International; Location; Magnetic Resonance Imaging; Manufacturer Name; Measures; Mental disorders; Methodology; Methods; Modeling; Optics; Oral; Perfusion; Permeability; Radiation; Recording of previous events; Research; Research Personnel; Safety; Schedule; Scientist; Secure; Social Network; Techniques; Temperature; Time; Transcranial magnetic stimulation; Translations; Travel; Ultrasonics; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Woman; Work; arterial spin labeling; biomarker development; brain computer interface; career; clinical application; clinical biomarkers; design; image guided therapy; improved; in vivo; industry partner; interest; meetings; member; metropolitan; nervous system disorder; neural circuit; neuromechanism; neurophysiology; neuroregulation; novel strategies; posters; pre-clinical; programs; symposium

Project Summary/Abstract: During recent years, neuromodulation techniques such as transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS) and deep brain stimulation (DBS), as well as alternative methods using optical and ultrasonic modulations, have become an important means to study how complex neural circuits interact in the brain, to manipulate human cognition and to treat brain disorders. Magnetic resonance imaging (MRI) can now be performed either concurrently with or pre and post these neuromodulation techniques to visualize their effects on the human brain, to understand the neurophysiological mechanism and to improve their efficacy. This topic is highly relevant to the theme and growing interests of ISMRM for MRI guided therapy and MRI with implants. It also aligns with the goals of the NIH BRAIN Initiative and public interest in brain-computer interfaces such as Elon Musk’s Neuralink. The proposed ISMRM workshop on “MRI in Neuromodulation: Target Engagement, Neural Mechanism, and Biomarker Development” will bring together a diverse group of scientists and clinicians as well as industry partners who are interested in developing and applying advanced MRI techniques to visualize, understand and quantify neuromodulation effects on the human brain. This workshop will be the first of its kind on the topic of MRI in neuromodulation in ISMRM history. The proposed 2.5 days workshop will take place Oct 17-19, 2022 on the NIH campus in Bethesda MD. The program will be designed for both senior investigators and junior scientists. The organizing committee will also emphasize attendance by trainee members of ISMRM, underrepresented groups and engage the international research community, and will work with industry partners to secure funding to provide travel support for trainees. The meeting will include invited and proffered oral presentations as well as short power-pitch poster sessions. The workshop’s schedule will integrate presentations with ample discussion periods covering advances in various MRI techniques for neuromodulation (electromagnetic field mapping, functional connectivity, arterial spin labeled perfusion and permeability, temperature and acoustic radiation force imaging etc), pre-clinical animal models and cellular-level mechanisms of neuromodulation, and safety issues related to MRI with neuromodulation devices. Existing and emerging clinical applications for MRI in neuromodulation and biomarker development will be discussed between academic and industry partners.

项目摘要/摘要： 近年来，神经调节技术如经颅直流电刺激（tDCS）、 经颅磁刺激（TMS）和深部脑刺激（DBS），以及使用的替代方法 光学和超声波调制，已成为研究复杂神经回路如何进行的重要手段 在大脑中相互作用，操纵人类认知并治疗大脑疾病。 （MRI）现在可以与这些神经调节技术同时或前后进行 可视化它们对人脑的影响，了解神经生理机制并提高 该主题与 ISMRM 对 MRI 引导治疗的主题和日益增长的兴趣高度相关。 它也符合 NIH BRAIN Initiative 的目标和公众对脑机的兴趣。 接口，例如 Elon Musk 的 Neuralink 提议的 ISMRM 研讨会“神经调节中的 MRI： “目标参与、神经机制和生物标志物开发”将汇集多元化的团队 对开发和应用先进技术感兴趣的科学家和牧师以及行业合作伙伴 MRI 技术可可视化、理解和量化神经调节对人脑的影响。 研讨会将是 ISMRM 历史上首次以 MRI 神经调节为主题的研讨会 提议的 2.5。 天研讨会将于 2022 年 10 月 17 日至 19 日在马里兰州贝塞斯达的 NIH 校区举行。 组委会还将强调为高级研究人员和初级科学家设计的。 ISMRM 的实习成员、代表性不足的群体出席并参与国际研究 社区，并将与行业合作伙伴合作，确保资金为学员提供差旅支持。 会议将包括受邀和口头报告以及简短的强力推介海报会议。 研讨会的日程安排将结合演讲和充足的讨论时间，涵盖各个方面的进展 用于神经调节的 MRI 技术（电磁场映射、功能连接、动脉自旋标记 灌注和渗透性、温度和声辐射力成像等）、临床前动物模型 神经调节的细胞水平机制，以及与神经调节 MRI 相关的安全问题 MRI 在神经调节和生物标志物开发中的现有和新兴临床应用将。 学术界和工业界合作伙伴之间进行讨论。