Application of an innovative enzyme-based technology for production of gluten-safe bread

应用创新酶技术生产无麸质面包

基本信息

  • 批准号:
    10110007
  • 负责人:
  • 金额:
    $ 12.74万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Launchpad
  • 财政年份:
    2024
  • 资助国家:
    英国
  • 起止时间:
    2024 至 无数据
  • 项目状态:
    未结题

项目摘要

In the UK, more than 13 million individuals suffer from gluten allergies, such as gluten ataxia, non-coeliac gluten sensitivity and irritable bowel syndrome, triggered by specific parts of gluten proteins which can be found in wheat, barley, and other grain flours commonly used in bread, pasta, and everyday food items. Additionally, many people experience gluten sensitivities, while approximately 600,000 individuals in the UK have coeliac disease, an allergy to gluten that can be life-threatening.The growing awareness of gluten-related health issues has led to a significant expansion in gluten-free food options. Roughly one in five UK shoppers now regularly purchase gluten-free products, and most supermarkets offer a wide range of gluten-free bread, cakes, pasta, and beer. However, consumers often find themselves disappointed by the texture and taste of gluten-free bread, which tends to come at a higher price.Our project aims to revolutionise the bread-making industry by developing an innovative solution that resembles the taste and texture of traditional bread in gluten-free alternatives. Current approaches rely on gluten-free flours such as rice flour, tapioca starch, and potato starch, resulting in increased costs and noticeable differences in texture and taste. Our unique solution involves a novel set of enzymes capable of selectively deactivating the harmful parts of gluten protein, which are responsible for gluten-related issues, while preserving the remaining gluten protein that gives bread its familiar texture. As a result, the final bread product can be characterised as gluten-safe rather than gluten-free. By targeting these specific components, we aim to eliminate gluten-related problems without compromising the overall texture and flavour of the bread.The project involves multiple stages. Currently, we are characterising the enzymes, followed by optimising their activity to achieve the desired gluten content in bread. Subsequently, we will move on to the dough-making phase, ensuring that the enzymes do not affect the texture of the bread. Finally, we will conduct sensory tests to ensure that the gluten-safe bread tastes the same as regular bread.This solution offers an authentic and healthier alternative that closely resembles conventional bread in both texture and flavour, all at an affordable price. Our ultimate goal is to create a gluten-safe world full of flavour.
在英国,超过 1300 万人患有麸质过敏,例如麸质共济失调、非乳糜泻麸质敏感性和肠易激综合症,这些过敏是由小麦、大麦和其他谷物粉中常见的麸质蛋白的特定部分引发的用于面包、面食和日常食品。此外,许多人对麸质过敏,而英国大约有 600,000 人患有乳糜泻,这是一种可能危及生命的麸质过敏。人们对麸质相关健康问题的认识不断提高,导致无麸质食品的大幅增加选项。大约五分之一的英国购物者现在定期购买无麸质产品,大多数超市都提供各种无麸质面包、蛋糕、面食和啤酒。然而,消费者经常发现自己对无麸质面包的质地和味道感到失望,而且无麸质面包的价格往往更高。我们的项目旨在通过开发一种类似于传统面包味道和质地的创新解决方案来彻底改变面包制作行业。无麸质面包替代品。目前的方法依赖于无麸质面粉,如米粉、木薯淀粉和马铃薯淀粉,导致成本增加,并且质地和味道存在明显差异。我们独特的解决方案涉及一组新型酶,能够选择性地灭活面筋蛋白中的有害部分(这些部分是导致面筋相关问题的原因),同时保留剩余的面筋蛋白,使面包具有熟悉的质地。因此,最终的面包产品可以被描述为无麸质而不是无麸质。通过针对这些特定成分,我们的目标是在不影响面包整体质地和风味的情况下消除与麸质相关的问题。该项目涉及多个阶段。目前,我们正在对酶进行表征,然后优化其活性,以达到面包中所需的麸质含量。随后,我们将进入面团制作阶段,确保酶不会影响面包的质地。最后,我们将进行感官测试,以确保无麸质面包的味道与普通面包相同。该解决方案提供了一种正宗、更健康的替代品,其质地和味道与传统面包非常相似,而且价格实惠。我们的最终目标是创造一个充满风味的无麸质世界。

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

数据更新时间:{{ journalArticles.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ monograph.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ sciAawards.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ conferencePapers.updateTime }}

{{ item.title }}
  • 作者:
    {{ item.author }}

数据更新时间:{{ patent.updateTime }}

其他文献

Products Review
  • DOI:
    10.1177/216507996201000701
  • 发表时间:
    1962-07
  • 期刊:
  • 影响因子:
    2.6
  • 作者:
  • 通讯作者:
Farmers' adoption of digital technology and agricultural entrepreneurial willingness: Evidence from China
  • DOI:
    10.1016/j.techsoc.2023.102253
  • 发表时间:
    2023-04
  • 期刊:
  • 影响因子:
    9.2
  • 作者:
  • 通讯作者:
Digitization
References
Putrescine Dihydrochloride
  • DOI:
    10.15227/orgsyn.036.0069
  • 发表时间:
    1956-01-01
  • 期刊:
  • 影响因子:
    0
  • 作者:
  • 通讯作者:

的其他文献

{{ item.title }}
{{ item.translation_title }}
  • DOI:
    {{ item.doi }}
  • 发表时间:
    {{ item.publish_year }}
  • 期刊:
  • 影响因子:
    {{ item.factor }}
  • 作者:
    {{ item.authors }}
  • 通讯作者:
    {{ item.author }}

{{ truncateString('', 18)}}的其他基金

An implantable biosensor microsystem for real-time measurement of circulating biomarkers
用于实时测量循环生物标志物的植入式生物传感器微系统
  • 批准号:
    2901954
  • 财政年份:
    2028
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Exploiting the polysaccharide breakdown capacity of the human gut microbiome to develop environmentally sustainable dishwashing solutions
利用人类肠道微生物群的多糖分解能力来开发环境可持续的洗碗解决方案
  • 批准号:
    2896097
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
A Robot that Swims Through Granular Materials
可以在颗粒材料中游动的机器人
  • 批准号:
    2780268
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Likelihood and impact of severe space weather events on the resilience of nuclear power and safeguards monitoring.
严重空间天气事件对核电和保障监督的恢复力的可能性和影响。
  • 批准号:
    2908918
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Proton, alpha and gamma irradiation assisted stress corrosion cracking: understanding the fuel-stainless steel interface
质子、α 和 γ 辐照辅助应力腐蚀开裂:了解燃料-不锈钢界面
  • 批准号:
    2908693
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Field Assisted Sintering of Nuclear Fuel Simulants
核燃料模拟物的现场辅助烧结
  • 批准号:
    2908917
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Assessment of new fatigue capable titanium alloys for aerospace applications
评估用于航空航天应用的新型抗疲劳钛合金
  • 批准号:
    2879438
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Developing a 3D printed skin model using a Dextran - Collagen hydrogel to analyse the cellular and epigenetic effects of interleukin-17 inhibitors in
使用右旋糖酐-胶原蛋白水凝胶开发 3D 打印皮肤模型,以分析白细胞介素 17 抑制剂的细胞和表观遗传效应
  • 批准号:
    2890513
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
CDT year 1 so TBC in Oct 2024
CDT 第 1 年,预计 2024 年 10 月
  • 批准号:
    2879865
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship
Understanding the interplay between the gut microbiome, behavior and urbanisation in wild birds
了解野生鸟类肠道微生物组、行为和城市化之间的相互作用
  • 批准号:
    2876993
  • 财政年份:
    2027
  • 资助金额:
    $ 12.74万
  • 项目类别:
    Studentship

相似国自然基金

白念珠菌F1Fo-ATP合酶中创新药靶的识别与确认研究
  • 批准号:
  • 批准年份:
    2022
  • 资助金额:
    52 万元
  • 项目类别:
    面上项目
基于CRISPR-Cas12a核酸酶的高效植物启动子编辑系统创新及应用
  • 批准号:
  • 批准年份:
    2022
  • 资助金额:
    54 万元
  • 项目类别:
    面上项目
毛茛科产二萜生物碱性状的发生与创新:基于贝壳杉烯氧化酶基因(KO)的功能歧化
  • 批准号:
  • 批准年份:
    2022
  • 资助金额:
    54 万元
  • 项目类别:
    面上项目
病原体艰难梭菌中创新药靶金属酶的化学生物学研究
  • 批准号:
    21977017
  • 批准年份:
    2019
  • 资助金额:
    66 万元
  • 项目类别:
    面上项目

相似海外基金

Discreet Wearable device for Continuous Real-time Monitoring of Alcohol
用于连续实时监测酒精浓度的谨慎可穿戴设备
  • 批准号:
    10547664
  • 财政年份:
    2022
  • 资助金额:
    $ 12.74万
  • 项目类别:
An innovative proof-of-concept approach to identify age-modulating drugs capable of reversing inflammation and re-setting the epigenetic clock
一种创新的概念验证方法,用于识别能够逆转炎症和重置表观遗传时钟的年龄调节药物
  • 批准号:
    10264863
  • 财政年份:
    2020
  • 资助金额:
    $ 12.74万
  • 项目类别:
An innovative proof-of-concept approach to identify age-modulating drugs capable of reversing inflammation and re-setting the epigenetic clock
一种创新的概念验证方法,用于识别能够逆转炎症和重置表观遗传时钟的年龄调节药物
  • 批准号:
    10040501
  • 财政年份:
    2020
  • 资助金额:
    $ 12.74万
  • 项目类别:
Clinical platform for high-throughput analyses of extracellular vesicles
细胞外囊泡高通量分析的临床平台
  • 批准号:
    10462501
  • 财政年份:
    2018
  • 资助金额:
    $ 12.74万
  • 项目类别:
Clinical platform for high-throughput analyses of extracellular vesicles
细胞外囊泡高通量分析的临床平台
  • 批准号:
    9754806
  • 财政年份:
    2018
  • 资助金额:
    $ 12.74万
  • 项目类别:
{{ showInfoDetail.title }}

作者:{{ showInfoDetail.author }}

知道了