Administrative Core

行政核心

• 批准号: 10518244
• 负责人: Pankaj Kumar Singh
• 金额: $ 11.83万
• 依托单位: UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-20 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10518244
• 关键词: Advisory Committees; Advocate; Area; Basic Science; Bioinformatics; Biometry; Cancer Biology; Cancer Center; Collaborations; Communication; Communities; Data; Development; Environment; Faculty; Fostering; Funding Agency; Future; Goals; Grant; Human Resources; Immune; Information Dissemination; Infrastructure; Intervention; Joints; Laboratories; Lead; Leadership; Link; Malignant Neoplasms; Malignant neoplasm of pancreas; Medical center; Metabolic; Metabolism; Monitor; National Cancer Institute; Nebraska; Occupational activity of managing finances; Organoids; Pilot Projects; Progress Reports; Records; Research; Research Personnel; Research Project Grants; Resistance; Resources; Schedule; Science; Scientist; Signal Transduction; Stromal Neoplasm; Students; Talents; Technical Expertise; Testing; Tissues; Translational Research; Travel; Universities; Work; anticancer research; cancer education; cancer therapy; data management; graduate student; innovation; interest; meetings; member; mouse model; neoplasm resource; next generation; novel; novel therapeutic intervention; operation; prevent; programs; prospective; resistance mechanism; therapy resistant; translational cancer research; translational pipeline; translational research program; tumor; tumor metabolism; web portal

ADMINISTRATIVE CORE Abstract The administrative core will lead, manage, and support all activities of the Acquired Resistance to Therapy Network (ARTNet) Center for Pancreatic Cancer (ACPC). It will represent ACPC at the trans-ARTNet network activities, and in interactions with NCI. The ARTNet administrative core will be responsible for managing the activities of the synergistic research ACPC projects with scientific and technical expertise and resources in the areas of therapy resistance, signaling, metabolism, pancreatic cancer biology, organoid and mouse models, immune and non-immune stroma, and PDAC tissues for studying the acquired therapy resistance in cancer. The core leadership will provide expertise spanning the basic to translational spectrum, consistent with the overarching theme of ACPC, with track records of building and guiding large scientific teams to successfully advance fields in transformative ways. We will utilize strategic management with innovative approaches, including an educational component to bring new talent into the field, engage diverse teams to facilitate new ideas, leverage national talent pertinent to the proposed goals, engage university leadership in building support for cutting-edge science, and utilize dedicated university expertise to facilitate engagement with basic and translational research programs to grow ARTNet centric interests. The administrative core will provide support for personnel involved in the administration, coordination, communication, biostatistics, and bioinformatics to support the ARTNet activities within the center and campus, other ARTNet centers, ARTNet Coordinating Data and Management Center (CDMC) and National Cancer Institutes (NCI). The administrative core will also provide scientific oversight, result dissemination, budgetary oversight, and clerical functions associated with the overall research program in this ACPC application. The core will implement center-wide activities which include, developing new collaborations on the ACPC projects, organize annual retreat, support acquired cancer therapy resistance seminar speakers within various academic units, advocate for the next generation of scientists (graduate students, postdoctoral researchers, and junior faculty) in the ACPC member laboratories. Finally, the administrative core will represent ACPC on the ARTNet steering committee.