Administrative Core

行政核心

• 批准号: 10505612
• 负责人: MARGIE L. CLAPPER
• 金额: $ 25.89万
• 依托单位: RESEARCH INST OF FOX CHASE CAN CTR
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10505612
• 关键词: Attention; Biological; Collaborations; Communication; Communities; Consultations; Data; Educational workshop; Ensure; Evaluation; Fox Chase Cancer Center; Goals; Hereditary Neoplastic Syndromes; Informatics; Infrastructure; Intercept; Interdisciplinary Study; Laboratory Research; Leadership; Malignant Neoplasms; Molecular Target; Monitor; Prevention; Productivity; Reproducibility; Research; Research Activity; Research Personnel; Research Project Grants; Resource Sharing; Resources; Technical Expertise; Validation; cancer prevention; conflict resolution; data resource; efficacy testing; in vivo; meetings; member; multidisciplinary; pre-clinical; precision cancer prevention; programs; screening; skills; success; targeted agent

PROJECT SUMMARY - ADMINISTRATIVE CORE The Administrative Core will provide the infrastructure required to ensure efficient coordination, integration, planning, and evaluation of all agent discovery activities associated with the proposed CAP-IT Center. The Core provides an integrated multidisciplinary framework for scientific collaboration among the participating members and Shared Resources at FCCC. To facilitate productivity, the Administrative Core will provide fiscal management and clerical support, as well as ensure scientific rigor, data reproducibility, attention to important biological variables, transparency, and consistent communication. Importantly, the Administrative Core will serve as a liaison with the NCI and other Specialized CAP-IT Centers, and leverage the support of the Informatics Core to effectively engage with the Data and Resource Coordinating Center. Active participation of CAP-IT members in meetings, workshops and activities of the CAP-IT Network will be coordinated through the Administrative Core. These activities will be accomplished according to four specific aims to: 1) Maintain an effective framework of well-integrated multidisciplinary research activities by applying strong communication and organizational skills, and frequently monitoring research progress; 2) Promote trans-Network collaborations by coordinating and participating in CAP-IT Network meetings, and organizing inter-programmatic seminars and workshops; 3) Engage early-stage investigators in precision cancer prevention – interception research and disseminate findings and capabilities to the scientific community; and 4) Evaluate the progress of the proposed CAP-IT Center using standard deliverables and defined metrics and milestones of success. The Leadership Team, comprised of accomplished investigators with expertise in hereditary cancer syndromes, target validation, agent screening, in vivo efficacy testing, and informatics, will provide oversight of all aspects of the research projects, and make informed decisions at critical junctures of the discovery pipeline. In close consultation with the NCI, the FCCC CAP-IT will leverage its unique resources and technical expertise to fuel the discovery of agents for cancer prevention and interception within the CAP-IT Network and beyond.

项目摘要 - 行政核心 行政核心将提供所需的基础架构，以确保有效的协调，集成， 计划和评估与拟议的CAP-IT中心相关的所有代理发现活动。核心 为参与成员之间的科学合作提供了一个综合的多学科框架 并在FCCC共享资源。为了促进生产力，行政核心将提供财政 管理和文书支持，并确保科学严谨，数据复制，关注重要的 生物学变量，透明和一致的沟通。重要的是，行政核心将服务 作为与NCI和其他专业的CAP-IT中心的联络，并利用信息学的支持 有效地参与数据和资源协调中心的核心。 CAP-IT的积极参与 CAP-IT网络的会议，研讨会和活动的成员将通过 行政核心。这些活动将根据四个具体目标来完成：1）维护 通过运用强烈的沟通和 组织技能，并经常监视研究进度； 2）通过 协调和参加CAP-IT网络会议，并组织程序间的半手 讲习班； 3）让早期调查人员参与预防精确癌症 - 拦截研究和 向科学界传播发现和能力； 4）评估提议的进度 CAP-IT中心使用标准可交付成果以及成功的指标和成功的里程碑。领导 团队完成了有成就的研究人员，具有珍藏癌综合症专业知识，目标验证， 代理筛选，体内效率测试和信息信息，将对研究的各个方面进行监督 项目，并在发现管道的关键关键时刻做出明智的决定。密切协商 NCI，FCCC CAP-IT将利用其独特的资源和技术专业知识来促进发现 CAP-IT网络及其他地区内预防癌症和拦截的代理。