PrEP Initiation and Adherence among Black SMM: A Social Network-Level Intervention

黑人 SMM 中 PrEP 的启动和坚持：社交网络级别的干预

• 批准号: 10493327
• 负责人: DEMARC A HICKSON
• 金额: $ 30.99万
• 依托单位: US HELPING US, PEOPLE INTO LIVING, INC.
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2023-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10493327
• 关键词: 18 year old; AIDS prevention; Address; Adherence; Age; Alcohols; Americas; Area; Behavior; Behavioral; Bisexual; Black race; Caring; Characteristics; Clinical; Communication; Communities; Data; Decision Making; Diagnosis; Diffuse; Diffusion of Innovation; Discrimination; Drug usage; Epidemic; Evaluation; Failure; Focus Groups; Gays; Goals; HIV; HIV Seronegativity; HIV diagnosis; Health system; Homophobia; Human immunodeficiency virus test; Incidence; Individual; Influentials; Injectable; Interpersonal Relations; Intervention; Latino; Manuals; Medical; Methodology; Methods; Modeling; Motivation; Network-based; Outcome; Participant; Phase; Pilot Projects; Population; Prevalence; Prevention; Prevention strategy; Primary Prevention; Procedures; Protocols documentation; Provider; Public Health; Recommendation; Research; Research Personnel; Resource-limited setting; Resources; Role; Services; Social Network; Spottings; Testing; Trust; United States National Institutes of Health; Universities; Washington; Work; acceptability and feasibility; age group; aged; base; black men; community based research; condoms; cost effective; design; effectiveness study; experience; health care settings; high risk; homonegativity; innovation; intervention delivery; intervention refinement; member; men; men' s group; multidisciplinary; patient-clinician communication; peer; pre-exposure prophylaxis; preference; prospective; racial disparity; racism; recruit; sexual minority men; skills; social; social norm; social stigma; social structure; substance use; theories; therapy development; uptake

PROJECT SUMMARY Background. The social networks of Black men, including Black gay, bisexual and other Black sexual minority men (SMM), influence their decision-making and HIV-related behaviors (e.g., condom use, HIV testing). Social networking strategies (SNS) interventions have been successful at increasing HIV testing among Black SMM who had never been tested and with unknown HIV status in Washington, D.C. (McCree et al., 2013; Baytop et al., 2014). A recent differential effectiveness study among Black SMM in Washington, DC (conducted at Us Helping Us) demonstrated SNS to be superior to venue testing and partner services in recruiting men that had never been tested (Baytop et al., 2014). SNS interventions also circumvent structural barriers to pre-exposure prophylaxis (PrEP) such as stigma, discrimination and medical mistrust. The proposed study aims are to design and open-phase pilot a low-intensity, cost-effective SNS intervention to increase PrEP initiation among Black SMM. This is critical because Black SMM have the highest HIV incidence in the U.S. and based on current HIV prevention, treatment and care rates, 50% of Black SMM will acquire HIV in their lifetime compared with ~10% of White SMM and 25% of Latino SMM Importantly, this highlights a critical failure of the U.S. public health system. Therefore, focused HIV prevention and social network-based intervention efforts, such as SNS, are warranted to meet the unique needs of Black SMM. Overview of project. The first 12 months (Phase 1: Formative Research) will be an intervention development/adaptation phase. Using a community-based participatory approach (n=18 age- and PrEP use profile-specific focus groups, of at least 4-5 participants each, totaling 72-90), participants will be asked about the social network dynamics and characteristics (e.g., influential network members, communication about PrEP as an HIV prevention method) that influenced their decision to initiate PrEP. Among participants with no PrEP use, they will be asked about the acceptability and feasibility of talking with PrEP-using Black SMM within their respective social network to support initiation along with preferences for relevant PrEP-related information from peers. The following 12 months (Phase 2: Open-phase Pilot Study) will involve conducting an open pilot of the SNS intervention, in up to six batches of up to 5 participants (n=30), allowing for further intervention refinement. This will allow us to demonstrate participant feasibility and acceptance, which includes the ability to recruit network members, feasibility of intervention delivery, and changes in participant behaviors. It will allow for further evaluation of the feasibility of all study procedures, refinement of intervention manual, and provide pilot data to submit an NIH application for a larger prospective trial. Therefore, the expected outcome is a culturally relevant SNS intervention to increase PrEP initiation among Black SMM through PrEP-using social network members.

项目摘要 背景。黑人的社交网络，包括黑人同性恋，双性恋和其他黑人性 少数民族（SMM），影响他们的决策和与HIV相关的行为（例如，使用避孕套，艾滋病毒 测试）。社交网络策略（SNS）干预措施已成功增加HIV测试 在从未接受过测试并且在华盛顿特区的HIV状况未知的黑人SMM中（McCree ET Al。，2013年； Baytop等，2014）。华盛顿特区Black SMM的最新差异有效性研究 （在我们的帮助下进行）证明SNS优于场地测试和合作伙伴服务 从未经过测试的招聘男人（Baytop等，2014）。 SNS干预措施也规避结构 暴露前预防（PREP）的障碍，例如污名，歧视和医疗不信任。提议 研究目的是设计和开放式飞行员进行低强度，具有成本效益的SNS干预以增加准备 黑色SMM之间的启动。这很关键，因为黑人SMM在美国的HIV发病率最高 并基于当前的艾滋病毒预防，治疗和护理率，黑人SMM的50％将在其中获取HIV 终生与约10％的白色SMM和25％的拉丁裔SMM相比重要，这突出了一个关键 美国公共卫生系统的失败。因此，集中的艾滋病毒预防和基于社交网络的 有必要有必要满足Black SMM的独特需求，例如SNS。 项目概述。前12个月（第1阶段：形成性研究）将是一项干预 开发/适应阶段。使用基于社区的参与方法（n = 18岁和准备使用 特定于个人资料特定的焦点小组，每个参与者至少有4-5个参与者，总计72-90），将询问参与者 社交网络动态和特征（例如，有影响力的网络成员，有关准备的沟通 作为预防艾滋病毒的方法），影响了他们启动准备的决定。在没有准备的参与者中 使用，将询问他们在他们的中与预备使用黑色SMM交谈的可接受性和可行性 各自的社交网络支持启动以及偏好从 同龄人。在接下来的12个月（阶段2：开放相试验研究）将涉及进行开放式飞行员 SNS干预，最多六批最多5名参与者（n = 30），可以进一步干预 精致。这将使我们能够证明参与者的可行性和接受，其中包括 招募网络成员，干预交付的可行性以及参与者行为的变化。它将允许 为了进一步评估所有研究程序的可行性，简化干预手册，并提供 试点数据提交NIH申请进行更大的前瞻性试验。因此，预期的结果是 与文化相关的SNS干预措施，通过预先使用社会来增加黑人SMM的准备 网络成员。

项目成果

Psychometric Testing of the Daily Spiritual Experiences Scale (DSES) Among Black Gay, Bisexual, and Other Sexual Minority Men (SMM) and Black Transwomen in the Deep South: The MARI Study.

对南方腹地的黑人同性恋、双性恋和其他性少数男性 (SMM) 以及黑人跨性别女性的日常精神体验量表 (DSES) 进行心理测量测试：MARI 研究。

• DOI: 10.1007/s10943-022-01516-6
• 发表时间: 2022
• 期刊: Journal of religion and health
• 影响因子: 2.8
• 作者: Hickson,DeMarcA;He,Ying;Odusanya,Anne;Smith,AdamE;Ogunbajo,Adedotun;Smallwood,StacyW
• 通讯作者: Smallwood,StacyW