Development of a Multi-sensory Rehabilitation Program for People with Ultra Low Vision

为超低视力患者制定多感官康复计划

基本信息

批准号：
10480053
负责人：
Arathy Ganga Kartha
金额：
$ 9.75万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-30 至 2023-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10480053
关键词：
Address American Area Auditory Blindness Canada Cream Cues Data Development Devices Evidence based program Eye Goals Hand Impairment Individual Institutes Knowledge Letters Life Light Location Measures Mentors Methods Mission Modeling Outcome Outcome Measure Outcomes Research Participant Patients Pattern Performance Persons Phase Play Population Prosthesis Protocols documentation Psychophysics Quality of life Questionnaires Recommendation Recovery Rehabilitation Outcome Rehabilitation therapy Research Residual state Retina Role Sensory Shapes Source Space Perception Tactile Techniques Technology Touch sensation Training Training Programs Tube United States National Institutes of Health Universities Vision Visual Visual impairment Washington Weight Work age related aging population auditory feedback base blind career design effectiveness evaluation effectiveness study evidence base experimental study eye hand coordination feasibility testing gene therapy grasp haptic feedback haptics improved information gathering innovation multimodality multisensory performance tests programs rehabilitation research rehabilitation strategy sensory integration sensory substitution sight restoration skills stem cell therapy tool virtual environment virtual reality virtual reality environment vision rehabilitation visual feedback visual information visual performance way finding

项目摘要

Project Summary On the low vision continuum, the term ultra-low vision (ULV) defines vision good enough to be functional, but too limited to see detailed shapes, even the largest letters on the eye chart at 50 cm (VA<20/1600 or 1.9 log MAR). Approximately 1 million Americans currently suffer from severe visual impairment, and the number of individuals with ULV is expected to grow, both due to an aging population and due to vision restoration treatments (e.g., retinal and cortical prosthesis, stem cell therapy, gene therapy) that restore vision from total blindness to the ULV level. Indeed, the number of patients with ULV is expected to double by 2050. The current practice of visual rehabilitation in ULV is based on sensory substitution training. However, can visual input enhance functional performance using inputs from auditory and tactile senses? In this study we will evaluate the range of activities that can be performed with different levels of ULV; for which of these activities multisensory integration can enhance functional performance; test a pilot multisensory rehabilitation program; and develop and validate a rehabilitation program for ULV based on multisensory integration. During the mentored phase, we will assess visual performance using virtual reality (ULV lab at Johns Hopkins); use cue combination paradigms to assess if there is enhancement of performance using multisensory integration (VisCog lab at University of Washington, Seattle); and design and conduct a pilot multisensory rehabilitation program (CRIR at Université de Montreal, Canada). During the independent phase, I will expand my training to develop an evidence-based multisensory rehabilitation program for ULV that will be validated for use in ULV population. The outcomes of this research will have important implications on improving visual ability and integration of visual, auditory and haptic senses. A program better suited to ULV needs will have a significant impact on ULV individuals' quality of life. Currently, individuals with ULV are not served well by the vision rehabilitation programs that are available, in part because of the lack of tools to assess visual ability in any given ULV individual. People with ULV are generally encouraged to ignore their remaining vision in order to strengthen their non-visual skills. Many of them find this frustrating and unnecessary, become disillusioned, and avoid further rehabilitation training. Using the methods developed in this study, we will be able to measure functional vision and validate a vision rehabilitation program for people with ULV built on a multisensory approach. This study will bridge a critical knowledge gap in the field of rehabilitation for people with ULV.

项目摘要在低视力中，“超低视觉（ULV）”一词定义了足够好的视力，但也是如此限制以查看详细的形状，甚至是眼图上50厘米的最大字母（VA <20/1600或1.9 log Mar）。目前约有100万美国人患有严重的视觉障碍，并且个人数量随着人口老龄化和视力恢复治疗，随着ULV的增长（例如，视网膜和皮质假体，干细胞疗法，基因疗法），将视力从完全失明恢复到 ULV水平。实际上，ULV患者的数量预计到2050年。 ULV的康复基于感觉替代培训。但是，可视输入可以增强功能使用听觉和触觉感觉的输入的性能？在这项研究中，我们将评估活动范围可以用不同级别的ULV执行；这些活动中的哪一个多感官一体化可以增强功能性能；测试试点多感觉康复计划；并开发和验证基于多感官整合的ULV康复计划。在修订阶段，我们将评估使用虚拟现实（Johns Hopkins的ULV实验室）的视觉性能；使用提示组合范式评估如果使用多感官集成提高性能（华盛顿大学的Viscog Lab，西雅图）;设计和执行飞行员多感觉康复计划（蒙特利尔大学的CRIR，加拿大）。在独立阶段，我将扩大培训以开发基于证据的多感官将用于ULV的康复计划，该计划将在ULV人群中使用。这项研究的结果将对改善视觉能力以及视觉，听觉和狂热感觉的整合具有重要意义。一项更适合ULV需求的计划将对ULV个人的生活质量产生重大影响。现在，可用的视觉康复计划对患有ULV的个人无法很好地服务，部分原因是缺乏评估任何给定ULV个体视觉能力的工具。普遍鼓励有ULV的人忽略他们剩余的愿景，以增强他们的非视觉技能。他们中的许多人觉得这很沮丧并且不必要，幻灭并避免进一步的康复培训。使用开发的方法在这项研究中，我们将能够衡量功能视觉并验证人们的视觉康复计划使用ULV建立在多感官方法上。这项研究将弥合在领域的关键知识差距为患有ULV的人进行康复。

项目成果

期刊论文数量（3）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Poster Session: Development and validation of a virtual reality based toolkit to assess functional vision in Ultra Low Vision.

海报会议：开发和验证基于虚拟现实的工具包，以评估超低视力的功能性视力。

DOI：
10.1167/jov.23.11.55
发表时间：
2023
期刊：
Journal of vision
影响因子：
1.8
作者：
Kartha,Arathy;Sadeghi,Roksana;Swanson,Thom;Gee,Will;Dagnelie,Gislin
通讯作者：
Dagnelie,Gislin

Measuring visual information gathering in individuals with ultra low vision using virtual reality.

DOI：
10.1038/s41598-023-30249-z
发表时间：
2023-02-23
期刊：
SCIENTIFIC REPORTS
影响因子：
4.6
作者：
Kartha, Arathy;Sadeghi, Roksana;Bradley, Chris;Tran, Chau;Gee, Will;Dagnelie, Gislin
通讯作者：
Dagnelie, Gislin

Self-Reported Visual Ability Versus Task Performance in Individuals With Ultra-Low Vision.