Biostatistics Core

生物统计学核心

基本信息

批准号：
10478842
负责人：
Peng Huang
金额：
$ 13.38万
依托单位：
JOHNS HOPKINS UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-18 至 2024-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10478842
关键词：
Address Animals Basic Science Bioinformatics Biological Biometry Biostatistics Core Cancer Biology Clinical Sciences Collaborations Consultations Custom Data Data Analyses Data Discovery Data Storage and Retrieval Detection Development Ensure Equipment Faculty Funding Genome Genomics Goals Human Immunologics Information Storage K-Series Research Career Programs Laboratory Finding Learning Malignant Neoplasms Malignant neoplasm of ovary Manuscripts Methodology Modeling Monitor Morbidity - disease rate Morphologic artifacts Oncology Positioning Attribute Publications Quality Control Recording of previous events Research Design Research Personnel Research Project Grants Resource Sharing Resources Running Services Techniques Technology Testing Visualization Work Writing base cancer genetics cancer genomics cancer prevention cancer therapy data acquisition design genomic data in vivo innovation interest member mortality multidimensional data personalized medicine programs stem synergism therapeutic target tool

项目摘要

BIOSTATISTICS CORE: PROJECT SUMMARY The Biostatistics Core Resource will provide comprehensive biostatistics and bioinformatics consultation and collaboration to all Research Projects in the proposed Johns Hopkins Ovarian Cancer SPORE. Core members will work with project investigators across a wide spectrum of activities, encompassing data acquisition (including study design, feasibility of objectives, availability of public-access genomic information, and data storage), statistical quality control (including artifact detection and preprocessing of data from genomic technologies), data analysis (including visualization, biostatistical modeling, and assistance with manuscript writing), and development of innovative customized biostatistical methodologies and tools if required by specific projects. The proposed Ovarian Cancer SPORE Biostatistics Core is housed in the Division of Oncology Biostatistics and Bioinformatics of the Department of Oncology, an active and committed group of biostatistics and bioinformatics faculty members, with access to state-of-the art equipment and a broad range of expertise. This Core resource builds on expertise gained by Core members who actively participate in other SPOREs at Johns Hopkins. Core members have a strong commitment to this SPORE, stemming from: a) a history of collaboration with the investigators on this other research projects in ovarian cancer, b) an active and independently funded agenda of synergistic projects in cancer genetics and genomics, and c) a demonstrated interest and understanding of both the biological and analytical questions and challenges. All proposed Projects are anticipated to make use of this Resource.

生物统计学核心：项目摘要生物统计学核心资源将提供全面的生物统计学和生物信息学咨询以及在拟议的约翰·霍普金斯卵巢癌孢子中与所有研究项目的合作。核心成员将与各种活动中的项目调查人员合作，包括数据获取（包括研究设计，目标的可行性，公共访问基因组信息的可用性和数据存储），统计质量控制（包括基因组技术的数据检测和数据的预处理），数据分析（包括可视化，生物统计建模以及手稿写作的帮助）和如果特定项目的需要，开发创新的定制生物统计学方法和工具。这拟议的卵巢癌孢子生物统计学核心位于肿瘤学生物统计学和肿瘤学系的生物信息学，一组活跃而坚定的生物统计学和生物信息学教职员工，拥有最先进的设备和广泛的专业知识。这个核心资源基于由约翰·霍普金斯（Johns Hopkins）积极参与其他孢子的核心成员获得的专业知识。核成员对这孢子有坚定的承诺，源于：a）与研究人员研究了卵巢癌的其他研究项目，b）癌症遗传学和基因组学方面的协同项目，以及c）表现出对两者的兴趣和理解生物学和分析问题和挑战。预计所有提出的项目都将利用这一点资源。