Colorado HNC SPORE Developmental Research Program

科罗拉多州 HNC SPORE 发展研究计划

• 批准号: 10477468
• 负责人: MARY ELAINE REYLAND
• 金额: $ 9.56万
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10477468
• 关键词: Applications Grants; Basic Science; Budgets; Cancer Patient; Clinic; Clinical; Collaborations; Colorado; Communities; Data; Development; Ensure; Evaluation; Funding; Goals; Grant; Head and Neck Cancer; Hospitals; Institution; Intervention; Medical; Monitor; Patient-Focused Outcomes; Pilot Projects; Population; Process; Program Research Project Grants; Progress Reports; Research; Research Personnel; Resources; Scientist; Technology; Translational Research; Translations; United States Department of Veterans Affairs; Universities; anticancer research; career; flexibility; high risk; innovation; meetings; novel; programs; response; success; tool; translational potential; translational research program

SUMMARY, Developmental Research Program The Developmental Research Program (DRP) promotes new and innovative Head and Neck Cancer (HNC) “pilot” projects. The goal is to fund projects with high scientific merit that will greatly impact HNC research and/or have the potential for translation to the clinic and population and thus reduce the burden of HNC. A core priority will be to identify and support junior or mid-career investigators. The DRP will encourage projects with a) high perceived impact, b) translational potential that may be integrated into full projects within the SPORE, c) innovative ideas and approaches that generate new hypothesis and preliminary data that support new R01-type grant applications, d) new collaborations to develop novel research and research tools and/or e) high risk/high return projects that move the HNC field forward for basic science and/or clinical interventions. DRP projects will be funded through the SPORE budget and institutional matching funds. With the approval of the SPORE's External Advisory Board (EAB) and the NCI Translational Research Program (TRP) Director, DRP studies have the opportunity to become full projects as part of the flexibility option as long as they have translational research potential within the SPORE. Solicitations for DRP projects are made within UCCC covered institutions including University of Colorado campuses (Denver, Anschutz Medical Campus, Boulder) and Colorado State University. The SPORE Administrative Core will ensure that DRP resources are used effectively to cultivate our HNC research. An efficient process is in place for successful review, selection, and monitoring of DRP projects. The influx of research from HNC investigators or those with expertise outside of HNC that will develop innovative, high-risk research will catalyze significant advances in the understanding and treatment of HNC.

摘要，发展研究计划 发展研究计划（DRP）促进了新的和创新的头颈癌（HNC） “飞行员”项目。目的是为具有高科学优点的项目提供资金，这将极大地影响HNC研究和/或 有可能转化为诊所和人口，从而减少HNC的燃烧。核心优先级 将是识别和支持初级或中级研究人员。 DRP将鼓励a）高 感知的影响，b）翻译潜力，这些潜力可能被整合到孢子中的完整项目中，c） 创新思想和方法产生了支持新R01型的新假设和初步数据 授予应用程序，d）开发新型研究和研究工具的新合作和/或e）高风险/高 将HNC领域推向基础科学和/或临床干预措施的返回项目。 DRP项目将 通过孢子预算和机构匹配资金资助。在孢子的批准下 外部顾问委员会（EAB）和NCI转化研究计划（TRP）主任DRP研究已有 只要他们翻译研究 孢子内的潜力。在UCCC涵盖的机构中，对DRP项目的招标包括在内 科罗拉多大学校园（丹佛，安苏兹医学校园，博尔德）和科罗拉多州立大学。 孢子行政核心将确保有效地使用DRP资源来培养我们的HNC 研究。为了成功审查，选择和监视DRP项目的有效过程。这 HNC研究人员或HNC以外具有专业知识的研究人员的研究涌入，这些研究将发展创新， 高风险的研究将促进HNC理解和治疗方面的重大进展。