Research Education Component

研究教育部分

• 批准号: 10475322
• 负责人: Kyle M Walsh
• 金额: $ 25.84万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10475322
• 关键词: Address; Aging; Alzheimer' s Disease; Alzheimer' s disease related dementia; American; American Indians; Basic Science; Biological Markers; Biology of Aging; Capsicum; Clinic; Clinical; Clinical Investigator; Clinical Research; Collaborations; Communication; Community Developments; Development; Discipline; Doctor of Philosophy; Educational Curriculum; Educational workshop; Environment; Exposure to; Face; Faculty; Fostering; Foundations; Future; Goals; Health; Historically Black Colleges and Universities; Institution; Journals; Knowledge; Learning; Longevity; Manuscripts; Mediating; Medical; Medical Research; Medical Students; Mentors; Mentorship; Neurosciences; North Carolina; Outcome; Pathologic; Pathology; Patient Recruitments; Population; Positioning Attribute; Postdoctoral Fellow; Preventive measure; Research; Research Design; Research Ethics; Research Personnel; Research Support; Research Training; Resources; Sampling; Science; Scientist; Site; Specimen; Statistical Data Interpretation; Students; Talents; Training; Training Programs; Training and Education; Translational Research; Underserved Population; Universities; age related; base; biobank; career; disparity reduction; education research; experience; health care delivery; improved; innovation; insight; interdisciplinary collaboration; interest; medical specialties; multidisciplinary; next generation; novel; online course; posters; programs; research data dissemination; responsible research conduct; rural healthcare; summer research; symposium; targeted delivery; training opportunity

ABSTRACT - Research Education Component The primary goal of the Duke/UNC Alzheimer’s Disease Research Center (ADRC) Research Education Component (REC) is to develop future leaders in Alzheimer’s disease (AD) and AD-related dementias (AD+ADRD) research, including within the Center’s theme of identifying age-related changes across the lifespan that mediate the development, progression and experience of AD. There are unique challenges facing AD+ADRD research, including limited training in researchprinciples, a lack of early-career exposure to AD+ADRD research, and research silos that impede knowledge transfer between basic and clinical investigators. To overcome these challenges, the REC research training program will broadly disseminate a foundational AD+ADRD research curriculum spanning both basic and clinical research, delivered to five universities across North Carolina and made available to the public (Aim 1). In addition to delivering broad cross-campus AD+ADRD research education, the REC will solicit “REC Scholar” applications and select 2-4 scholars annually from a diverse pool of talented early-career AD+ADRD investigators (Aim 2). REC Scholars will receive intensive research training and tailored professional development under the guidance of a faculty mentorship team comprised of a clinical researcher and a basic scientist. The REC will expand the reach of its training program by leveraging existing training assets at Duke and UNC (e.g., Duke’s “Creating AD Researchers for the Next Generation” STARR Program (R38), UNC’s “Summer Research Training in Aging for Medical Students” (T35) and Duke’s Claude D. Pepper Older Americans Independence Center and Edward R. Roybal Center). The REC’s close integration with the other Duke/UNC ADRC cores provides synergistic interactions with key research training opportunities in specimen biobanking, statistical analysis, study design, pathologic sample analysis, patient recruitment, and research dissemination. The REC will diversify AD+ADRD researcher perspectives and the workforce by partnering with UNC Pembroke (a designated historically American Indian university), NC Central University (an historically black university), and East Carolina University (an institution with expertise in rural healthcare delivery) (Aim 3). Investigators and trainees at these institutions will participate in monthly research colloquia, the online curriculum, monthly journal clubs, research consultancies that leverage Duke/UNC expertise to augment AD+ADRD research at other sites, and the annual Symposium for Learning about Alzheimer’s disease-related Medical research at Duke and UNC (SLAM-DUNC), hosted by each institution in turn. REC programming will foster interest in AD+ADRD research and cultivate the multidisciplinary expertise needed in its next generation of leaders. By fostering interactions among investigators from different disciplines and backgrounds through the REC’s innovative and inclusive programming, the REC will develop new AD+ADRD researchers prepared to engage in interdisciplinary collaborations aimed at improving health outcomes and reducing disparities by bringing novel treatments to the clinic and novel preventive measures to the population.

摘要 - 研究教育部分 杜克/UNC阿尔茨海默氏病研究中心（ADRC）研究教育的主要目标 组成部分（REC）是发展阿尔茨海默氏病（AD）和与AD相关的痴呆症的未来领导者 （AD+ADRD）研究，包括在中心的主题中确定整个寿命中与年龄相关的变化 调解AD的发展，发展和经验。面临着独特的挑战 AD+ADRD研究，包括研究普通的有限培训，缺乏早期职业 AD+ADRD研究以及阻碍基本研究者和临床研究人员之间知识转移的研究筒仓。 为了克服这些挑战，REC研究培训计划将广泛传播基础 AD+ADRD研究课程涵盖基础研究和临床研究，交付给五所大学 北卡罗来纳州并向公众提供（AIM 1）。除了提供宽阔的跨校园AD+ADRD 研究教育，REC将征集“ Rec Scholar”的应用，并从每年选择2-4名学者 多样化的才华横溢的早期AD+ADRD调查员（AIM 2）。娱乐学者将得到密集的 在教职员工团队的指导下，研究培训和量身定制的专业发展 完成了临床研究人员和基础科学家。 REC将扩大其培训计划的影响力 通过利用Duke和UNC的现有培训资产（例如，Duke的“为下一个创建广告研究人员 UNC的“医学生夏季研究培训”（T35） 以及杜克大学的克劳德·D·佩珀（Claude D. REC与其他Duke/UNC ADRC核心的紧密整合提供了与Key的协同互动 标本生物库的研究培训机会，统计分析，研究设计，病理样本 分析，招募和研究传播。 REC将使AD+ADRD研究人员多样化 与UNC Pembroke合作的观点和劳动力 大学），北卡罗来纳大学（历史悠久的黑人大学）和东卡罗来纳大学（一个机构 具有粗略的医疗保健交付方面的专业知识（AIM 3）。这些机构的调查人员和学员将参加 在每月研究座谈会上 Duke/UNC的专业知识，以增强其他网站的AD+ADRD研究，以及年度学习研讨会 关于每个机构主持的杜克大学和UNC（SLAM-DUNC）与阿尔茨海默氏病有关的医学研究 反过来。 REC编程将促进对AD+ADRD研究的兴趣，并培养多学科专业知识 在下一代领导者中需要。通过促进来自不同学科的研究者之间的互动 以及通过REC的创新和包容性编程的背景，Rec将开发新的 AD+ADRD研究人员准备进行跨学科合作，以改善健康 通过将新的治疗方法带入诊所和新颖的预防措施来降低差异和降低差异 人口。