Informing treatment adaptation based on the interplay between behavioral undercontrol and context: an event-level study

根据行为失控和环境之间的相互作用来告知治疗适应：一项事件级研究

基本信息

批准号：
10474362
负责人：
Tim Janssen
金额：
$ 18.07万
依托单位：
BROWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2018
资助国家：
美国
起止时间：
2018-09-01 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10474362
关键词：
Acute Adolescent Adolescent Development Adult Affect Age Alcohol abuse Alcohol consumption Alcohols Assessment tool Behavior assessment Behavioral Characteristics Collection Complement Coupled Data Development Development Plans Ecological momentary assessment Environment Environmental Risk Factor Esthesia Etiology Event Female Adolescents Funding Future Gender Grain Health Heavy Drinking Human Impulsivity Individual Individual Differences Intervention Laboratories Laboratory Study Learning Life Link Location Male Adolescents Measures Mediating Mediation Mediator of activation protein Methods Modeling National Institute on Alcohol Abuse and Alcoholism Onset of illness Participant Patient Self-Report Pattern Persons Predisposition Process Reporting Research Role Secure Social Environment Supervision Surveys Technology Teenagers Testing Time Training United States Variant Violence Youth adolescent alcohol misuse alcohol availability alcohol consequences alcohol measurement alcohol related consequences alcohol risk alcohol use disorder base binge drinking career development computerized contextual factors design discounting drinking drinking behavior early drinking experience indexing individual variation legal drinking age mindfulness multilevel analysis peer prototype public health relevance recruit response sex social theories trait underage drinker underage drinking vehicular accident willingness

项目摘要

PROJECT SUMMARY Underage drinking in the United States is a serious health concern, with a multifaceted etiology and wide- ranging implications including risky situations (motor vehicle accidents, risky sex, and violence) and alcohol use disorder (adolescents have the highest rate of alcohol use disorder onset). Both environmental and individual characteristics are implicated in the development of adolescent drinking behavior. At the environmental level, social, locational, and situational context characteristics influence adolescent patterns of drinking. At the individual level, one of the strongest individual predictors of underage drinking is behavioral undercontrol (BU; e.g. impulsivity, sensation seeking). Interventions that target differences in BU successfully delay onset and reduce quantity of alcohol use in underage drinkers. However, research has shown that context characteristics, and differences in BU, meaningfully change drinking behavior. Hence, there is an opportunity to investigate how context effects differ by sex and are moderated by BU to produce heavy episodic drinking at the event level; by conducting time-sensitive research investigating how BU predicts self- selection into drinking contexts, and how BU subsequently moderates the impact of those contexts. This K01 proposal, titled “Informing treatment adaptation using fine-grained context data in adolescent alcohol use” proposes to collect fine-grained data that could inform context-sensitive interventions, by informing when, where, and with whom to intervene, along with adaptation to sex- or context-specific situations. Equal numbers of male and female adolescents (N = 120, ages 15-17 years) who report at least one heavy drinking episode in the past two weeks, will be recruited for a 17-day ecological momentary assessment (EMA) survey preceded by a single laboratory session. The laboratory session will include self-report and behavioral assessments of BU as well as environmental factors. The EMA will include random user prompts as well as self-initiated reports assessing alcohol use, social, locational, and situational context characteristics, along with assessments of BU prior to, and after, alcohol use. The project has three specific research aims: 1) Examine whether context mediates the effect of BU on adolescent drinking. 2) Examine whether BU moderates the role of context in predicting adolescent drinking. 3) Examine how drinking impacts impulsivity, and how this impact predicts alcohol consequences. By informing context-sensitive interventions based on findings, we will capitalize on technology that allows for context-appropriate prompts (“Just-in-time” interventions). The associated training plan will provide the candidate with the ability to independently conduct EMA surveys among adolescents and aid in securing future funding, becoming a substantive expert on event-level context characteristics and individual traits using fine-grained assessment tools, and informing treatment adaptations for individual-differences-based interventions. Thus, the project is aligned at multiple levels with NIAAA’s underage drinking research initiative into investigating factors that drive harmful adolescent alcohol use.

项目摘要美国的未成年饮酒是一个严重的健康问题，具有多方面的病因和广泛的饮酒。包括风险情况（汽车事故，风险性行为和暴力）和酒精的含义使用障碍（青少年的酒精使用障碍率最高）。环境和在青少年饮酒行为的发展中实施了个体特征。在环境层面，社会，位置和情境环境特征会影响青少年模式喝。在个人层面上，未成年人饮酒的个人预测指标之一是行为控制不足（bu;例如冲动性，寻求感觉）。成功针对BU的干预措施成功延迟发作并减少未成年人饮酒者的饮酒量。但是，研究表明上下文特征和BU的差异，有意义地改变了饮酒行为。因此，有一个调查上下文效果如何因性别而不同的机会，并由BU调节以产生沉重活动级别的情节饮酒；通过进行时间敏感的研究调查BU如何预测自我选择饮酒环境，以及BU随后如何缓和这些环境的影响。这个K01 提案，标题为“使用青少年饮酒中的细颗粒上下文数据告知治疗适应” 通过通知何时，收集可以为上下文敏感干预提供信息的细粒度数据的建议在哪里，与谁进行干预，并适应性别或上下文特定的情况。相等的数字男性和女性青少年（n = 120，年龄15-17岁），他们在过去的两个星期，将招募17天的生态瞬时评估（EMA）调查。通过一次实验室会议。实验室会议将包括自我报告和行为评估 BU以及环境因素。 EMA将包括随机用户提示以及自发的评估饮酒，社会，位置和情境环境特征的报告在使用酒精之前和之后对BU的评估。该项目具有三个特定的研究目的：1）检查上下文是否介导BU对青少年饮酒的影响。 2）检查BU是否适应角色预测青少年饮酒的背景。 3）检查饮酒如何影响冲动性，以及这如何影响预测酒精后果。通过基于发现的对上下文敏感的干预措施，我们将利用允许上下文提示的技术（“及时”干预措施）。这相关的培训计划将使候选人能够独立进行EMA调查在青少年中，并有助于获得未来的资金，成为事件级环境的实质专家使用细粒度评估工具的特征和个人特征，并告知治疗适应用于基于个人差异的干预措施。那就与NIAAA的项目保持一致未成年人饮酒研究计划研究了促进有害青少年饮酒的因素。