HIV self-testing with online supervision for Vietnamese MSM

越南男男性行为者艾滋病毒自我检测和在线监督

基本信息

批准号：
10471788
负责人：
THOMAS E GUADAMUZ
金额：
$ 15.36万
依托单位：
MAHIDOL UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-08-19 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10471788
关键词：
AIDS prevention Antigens Asia Awareness Behavioral Blood Bypass Caring Cellular Phone Chemoprophylaxis Cities Clip Collaborations Collection Communities Continuity of Patient Care Counseling DNA Data Diagnostic Diagnostic Reagent Kits Disease Early Diagnosis Enrollment Epidemic Epidemiology Event Feasibility Studies Focus Groups Funding Mechanisms HIV HIV Infections HIV Seronegativity Health Human immunodeficiency virus test Incidence Individual Internet Intervention Knowledge Laboratories Logistics Measures Modality Molecular Epidemiology Outcome Persons Pilot Projects Population Pre-Post Tests Prevalence Professional counselor Rapid diagnostics Reading Reporting Research Research Personnel Research Proposals Resources Risk Risk Reduction Sexual Partners Social Network Spottings Supervision Surveys Target Populations Technology Testing Thailand Time Translations Universities Unsafe Sex Videoconferencing Vietnam Virus acceptability and feasibility antibody diagnostic antiretroviral therapy base behavioral outcome care systems design experience improved interest men who have sex with men novel strategies pilot test prevent prevention service psychosocial rapid testing recruit self testing social culture social stigma standard of care transmission process treatment services uptake video delivery virtual willingness young men who have sex with men

项目摘要

PROJECT SUMMARY/ABSTRACT There is a concentrated HIV epidemic among young men who have sex with men in Vietnam where HIV incidence was reported to be 5.8 per 100 person-years, one of the highest incidences in the region. Regular (at least annual) HIV testing of YMSM of unknown or HIV negative serostatus is critical for timely linkage to HIV prevention services, such as risk reduction counseling and HIV chemoprophylaxis. Among YMSM unaware of an existing or new HIV infection, timely identification is necessary to increase linkage and initiation of antiretroviral treatment and care to improve disease outlook and prevent onward HIV transmission. However, structural, logistical and psychosocial barriers limit the uptake and retention of Vietnamese MSM in regular HIV testing, hindering the rollout of much needed HIV prevention and treatment services targeting this population. This study proposes the use of online HIV testing (OHT) as an alternative HIV testing modality to increase engagement, retention and linkage of YMSM in HIV prevention, treatment and care services. The specific aims of this research proposal are 1) To identify potential barriers and facilitators to uptake of OHT among YMSM; 2) to develop an empirical profile of barriers and facilitators to HIV testing among YMSM, including an estimate of the proportion of YMSM likely to participate in an OHT intervention; and 3) To conduct a preliminary assessment of the OHT intervention, including introduction of a new HIV rapid diagnostic antibody/antigen-based self-testing with an HIV counselor through video conferencing, and “real time” self-collected dried blood spot (DBS) technology with centralized HIV DNA testing. Results of rapid testing will be read- and of centralized testing will be delivered by video conference, followed by discussion, post-test counseling and linkage to care and treatment, in a 12-month pilot study. Particularly, logistical issues, concerns over rapid HIV self-testing, DBS self-collection and laboratory testing, reading or reporting of results by video conferencing will be assessed, as well as how OHT may help to overcome some of the existing barriers to venue-based HIV testing. Using new HIV diagnostic and online technologies, OHT may be a promising strategy to increase engagement, retention and linkage to HIV prevention, treatment and care services among Vietnamese YMSM.

项目摘要/摘要在越南与男人发生性关系的年轻人中，艾滋病毒的浓缩流行据报道，艾滋病毒事件为每100人年5.8，这是最高的该地区的发生率。未知或HIV的YMMM的常规（至少每年）HIV测试阴性血统对于及时与艾滋病毒预防服务联系至关重要，例如风险还原咨询和HIV化学预防。在YMSM中，不知道现有或新的艾滋病毒感染，及时识别是为了增加联系和主动性的必要身份抗逆转录病毒治疗和护理以改善疾病前景并防止艾滋病毒前进传播。但是，结构，后勤和社会心理障碍限制了摄取和在常规的艾滋病毒测试中保留越南MSM，阻碍了急需的推出针对该人群的艾滋病毒预防和治疗服务。这项研究提出了使用在线艾滋病毒测试（OHT）作为替代性艾滋病毒测试方式以增加参与度， YMSM在艾滋病毒预防，治疗和护理服务中的保留和联系。具体该研究建议的目的是1）确定潜在的障碍和促进者以吸收 YMSM中的OHT； 2）为艾滋病毒发展障碍和促进因子的经验概况 YMSM的测试，包括对可能参与的YMSM比例的估计值在OHT干预中； 3）对OHT进行初步评估干预措施，包括引入新的HIV快速诊断抗体/基于抗原通过视频会议与艾滋病毒咨询师进行自我测试，并自行收获“实时” 带有集中式HIV DNA测试的干血点（DBS）技术。快速测试的结果将通过视频会议进行阅读和集中测试，然后在12个月的飞行员中讨论，测试后咨询以及与护理和治疗的联系学习。特别是后勤问题，对快速艾滋病毒自我测试的担忧，DBS自我收集以及通过视频会议阅读或报告结果的实验室测试，将是经过评估，以及OHT如何帮助克服一些现有的障碍基于场地的艾滋病毒测试。使用新的HIV诊断和在线技术，OHT可能是有希望增加参与，保留和与HIV预防联系的策略，越南YMSM的治疗和护理服务。