Advance Clinical and Translational Research (Advance-CTR)

高级临床和转化研究（Advance-CTR）

基本信息

批准号：
10468390
负责人：
Sharon Irene Smith Rounds
金额：
$ 77.39万
依托单位：
BROWN UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2021
资助国家：
美国
起止时间：
2021-09-07 至 2023-07-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10468390
关键词：
Address Area Award Basic Science Big Data Biological Biometry Caring Clinical Clinical Research Clinical Sciences Clinical effectiveness Collaborations Communities Community Outreach Core Facility Data Development Discipline of Nursing Environment Epidemiology Evolution Extramural Activities Fostering Funding Funding Opportunities Future Goals Government Agencies Grant Health Health Policy Health Priorities Health Services Health system Healthcare Systems Home Hospitals Human Resources Infrastructure Institutes Institution Lead Longevity Mental Health Mentors Modeling National Institute of General Medical Sciences New England Nonprofit Organizations Outcome Pharmacy facility Pilot Projects Population Positioning Attribute Program Development Program Evaluation Protocols documentation Public Health Publications Research Research Design Research Infrastructure Research Personnel Research Proposals Research Support Resources Rhode Island Services Teacher Professional Development Testing Training Translating Translational Research United States National Institutes of Health Universities University Hospitals Vulnerable Populations bench to bedside biomedical informatics career career development clinical application clinical infrastructure clinical practice community engaged research community engagement community organizations coronavirus disease cost demographics health care delivery health disparity health equity hospital organization improved innovation laboratory development multidisciplinary organizational structure patient oriented prevent programs success translational research program translational scientist virtual

项目摘要

ABSTRACT – OVERALL The universities, hospitals, government agencies and community organizations in Rhode Island are well positioned to bridge the gaps between the worlds of clinical and basic science. Rhode Island’s small size, population demographics, and organizational structure are assets and present opportunities to implement and test transformative clinical and translational research. The health care delivery environment within the state is highly conducive to clinical research due to the relatively limited number of health care systems. Further contributing to Rhode Island’s translational research infrastructure are a number of well-organized Institutional Developmental Award (IDeA) Programs, each with core facility, faculty development and collaborative research resources. But despite Rhode Island’s impressive educational institutions, streamlined clinical environment, and successful IDeA sponsored research and mentoring programs, the majority of these resources have not been coordinately focused towards developing a multi-institutional, clinical and translational research infrastructure that would serve to improve the effectiveness of clinical practice and health care policy in Rhode Island. The objective of the Advance Clinical and Translation Research Award (Advance-CTR) is to bridge these infrastructure gaps by creating an overarching, multidisciplinary, central organization to better coordinate and leverage existing resources for program management and thereby provide the infrastructure necessary to address current and future health concerns in Rhode Island. The goals of the Advance-CTR are to: 1. Educate, mentor and encourage young investigators in clinical research professional development. 2. Eliminate the obstacles that may prevent researchers from pursuing clinical research initiatives that can lead to funded research programs. 3. Bring together the diverse clinical research resources to provide a virtual home that facilitates new collaborations and enhanced efficiencies. 4. Facilitate research to gather preliminary data necessary for developing competitive research proposals. 5. Provide contemporary infrastructure for clinical and translational research including research planning and implementation, advanced biostatistics and epidemiology support and biomedical informatics. 6. Foster coordination between translational researchers at our participating entities so as to create new productive collaborations with translational outcomes. 7. Sustain a clinical translational research environment by providing the necessary management and coordination of resources. 8. Create an innovative Tracking and Evaluation program that will combine support requests with use and cost data and apply lessons learned in the CTSA program to the CTR environment.

摘要 – 总体罗德岛州的大学、医院、政府机构和社区组织状况良好旨在弥合罗德岛州面积较小的临床和基础科学领域之间的差距，人口统计数据和组织结构是资产，并提供实施和实施的机会测试变革性临床和转化研究该州的医疗保健提供环境是。由于医疗保健系统数量相对有限，非常有利于临床研究。许多组织良好的机构为罗德岛州的转化研究基础设施做出了贡献发展奖 (IDeA) 项目，每个项目都有核心设施、教师发展和协作但是，尽管罗德岛州拥有令人印象深刻的教育机构，但简化了临床。环境、成功的 IDeA 赞助的研究和指导计划，其中大部分资源尚未协调集中用于发展多机构、临床和转化研究基础设施将有助于提高临床实践的有效性和罗德岛州的医疗保健政策高级临床和转化研究奖的目标。 (Advance-CTR) 旨在通过创建一个总体性的、多学科的、集中的解决方案来弥合这些基础设施差距。组织更好地协调和利用现有资源进行计划管理，从而提供解决罗德岛州当前和未来健康问题所需的基础设施。 Advance-CTR 的目的是： 1. 教育、指导和鼓励年轻研究者进行临床研究专业发展。 2. 消除研究人员进行临床研究活动时可能遇到的障碍导致资助的研究项目。 3. 汇集多样化的临床研究资源，提供一个虚拟的家，促进新的研究协作并提高效率。 4. 促进研究收集制定竞争性研究提案所需的初步数据。 5. 为临床和转化研究提供现代基础设施，包括研究规划和实施、先进的生物统计学和流行病学支持以及生物医学信息学。 6. 促进参与实体的转化研究人员之间的协调，以创造新的成果富有成效的合作与转化成果。 7. 通过提供必要的管理和支持来维持临床转化研究环境资源协调。 8. 创建一个创新的跟踪和评估计划，将支持请求与使用和成本数据并将 CTSA 计划中吸取的经验教训应用到 CTR 环境中。