Advance Clinical and Translational Research (Advance-CTR)

高级临床和转化研究（Advance-CTR）

• 批准号: 10468390
• 负责人: Sharon Irene Smith Rounds
• 金额: $ 77.39万
• 依托单位: BROWN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-07 至 2023-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10468390
• 关键词: Address; Area; Award; Basic Science; Big Data; Biological; Biometry; Caring; Clinical; Clinical Research; Clinical Sciences; Clinical effectiveness; Collaborations; Communities; Community Outreach; Core Facility; Data; Development; Discipline of Nursing; Environment; Epidemiology; Evolution; Extramural Activities; Fostering; Funding; Funding Opportunities; Future; Goals; Government Agencies; Grant; Health; Health Policy; Health Priorities; Health Services; Health system; Healthcare Systems; Home; Hospitals; Human Resources; Infrastructure; Institutes; Institution; Lead; Longevity; Mental Health; Mentors; Modeling; National Institute of General Medical Sciences; New England; Nonprofit Organizations; Outcome; Pharmacy facility; Pilot Projects; Population; Positioning Attribute; Program Development; Program Evaluation; Protocols documentation; Public Health; Publications; Research; Research Design; Research Infrastructure; Research Personnel; Research Proposals; Research Support; Resources; Rhode Island; Services; Teacher Professional Development; Testing; Training; Translating; Translational Research; United States National Institutes of Health; Universities; University Hospitals; Vulnerable Populations; bench to bedside; biomedical informatics; career; career development; clinical application; clinical infrastructure; clinical practice; community engaged research; community engagement; community organizations; coronavirus disease; cost; demographics; health care delivery; health disparity; health equity; hospital organization; improved; innovation; laboratory development; multidisciplinary; organizational structure; patient oriented; prevent; programs; success; translational research program; translational scientist; virtual

ABSTRACT – OVERALL The universities, hospitals, government agencies and community organizations in Rhode Island are well positioned to bridge the gaps between the worlds of clinical and basic science. Rhode Island’s small size, population demographics, and organizational structure are assets and present opportunities to implement and test transformative clinical and translational research. The health care delivery environment within the state is highly conducive to clinical research due to the relatively limited number of health care systems. Further contributing to Rhode Island’s translational research infrastructure are a number of well-organized Institutional Developmental Award (IDeA) Programs, each with core facility, faculty development and collaborative research resources. But despite Rhode Island’s impressive educational institutions, streamlined clinical environment, and successful IDeA sponsored research and mentoring programs, the majority of these resources have not been coordinately focused towards developing a multi-institutional, clinical and translational research infrastructure that would serve to improve the effectiveness of clinical practice and health care policy in Rhode Island. The objective of the Advance Clinical and Translation Research Award (Advance-CTR) is to bridge these infrastructure gaps by creating an overarching, multidisciplinary, central organization to better coordinate and leverage existing resources for program management and thereby provide the infrastructure necessary to address current and future health concerns in Rhode Island. The goals of the Advance-CTR are to: 1. Educate, mentor and encourage young investigators in clinical research professional development. 2. Eliminate the obstacles that may prevent researchers from pursuing clinical research initiatives that can lead to funded research programs. 3. Bring together the diverse clinical research resources to provide a virtual home that facilitates new collaborations and enhanced efficiencies. 4. Facilitate research to gather preliminary data necessary for developing competitive research proposals. 5. Provide contemporary infrastructure for clinical and translational research including research planning and implementation, advanced biostatistics and epidemiology support and biomedical informatics. 6. Foster coordination between translational researchers at our participating entities so as to create new productive collaborations with translational outcomes. 7. Sustain a clinical translational research environment by providing the necessary management and coordination of resources. 8. Create an innovative Tracking and Evaluation program that will combine support requests with use and cost data and apply lessons learned in the CTSA program to the CTR environment.

摘要 - 总体 罗德岛州的大学，医院，政府机构和社区组织很好 定位弥合临床和基础科学世界之间的差距。罗德岛的小规模， 人口统计学和组织结构是实施和 测试变革性临床和翻译研究。该州内的医疗保健提供环境是 由于医疗系统数量相对有限，因此对临床研究高度有效。更远 为罗德岛的转化研究基础设施做出贡献是许多组织良好的机构 开发奖（IDEA）计划，每个计划都有核心设施，教师发展和协作 研究资源。但是目的地罗德岛令人印象深刻的教育机构，简化了临床 环境和成功的想法赞助了研究和心理计划，其中大多数 资源尚未协调地致力于开发多机构，临床和 翻译研究基础设施将提高临床实践的有效性和 罗德岛州的医疗保健政策。提前临床和翻译研究奖的目标 （Advance-CTR）是通过创建一个总体，多学科的中心来弥合这些基础设施差距 组织以更好地协调和利用现有资源进行计划管理，从而 提供必要的基础设施来解决罗德岛当前和未来的健康问题。目标 Advance-ctr的内容是： 1。教育，心理和鼓励临床研究专业发展的年轻研究人员。 2。消除可能阻止研究人员追求临床研究计划的障碍 导致资助的研究计划。 3。将潜水员临床研究资源汇集在一起​​，提供一个虚拟房屋，以促进新 协作和提高效率。 4。促进研究以收集制定竞争性研究建议所需的初步数据。 5。为临床和翻译研究提供当代基础设施，包括研究计划 以及实施，先进的生物统计学和流行病学支持和生物医学信息。 6。培养我们参与实体的翻译研究人员之间的协调，以创建新的 与翻译成果的生产合作。 7.通过提供必要的管理和 资源协调。 8。创建一个创新的跟踪和评估程序，将支持请求与使​​用和 成本数据并将CTSA计划中学习的教训应用于CTR环境。