FASEB SRC: The Nuclear Bodies Conference: Hubs of Genomic Activity

FASEB SRC：核机构会议：基因组活动中心

• 批准号: 10467741
• 负责人: PAUL D. KAUFMAN
• 金额: $ 0.45万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-19 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10467741
• 关键词: Area; Attention; Award; Biochemistry; Biological Models; Biomedical Research; Biophysics; Canada; Cancer Biology; Cell Nucleus; Cell Proliferation; Cellular Structures; Cellular biology; Child Care; Collaborations; Data; Development; Developmental Biology; Diffusion; Disabled Persons; Disease; Eukaryotic Cell; Event; Explosion; Faculty; Family; Fostering; Funding; Future; Gene Expression; Gene Expression Regulation; Genome; Genomics; Grant; In Vitro; Individual; International; Investigation; Island; Lead; Link; Liquid substance; Malignant Neoplasms; Massachusetts; Membrane; Mentors; Mentorship; Minority Women; Nova Scotia; Nuclear; Oncoproteins; Oral; Participant; Persons; Phase; Postdoctoral Fellow; RNA metabolism; Research; Research Personnel; Resort; Role; Science; Scientist; Stereotyping; Structure; Systems Biology; Therapeutic; Time; Travel; Underrepresented Minority; Underrepresented Populations; Universities; Woman; base; cancer cell; care systems; career; career development; career networking; cell growth; cost; design; diversity and inclusion; gender diversity; genomic tools; global health; graduate student; in vivo Model; innovation; insight; interdisciplinary collaboration; interest; intermolecular interaction; medical schools; meetings; member; mid-career faculty; novel; posters; professor; programs; social; summer research; symposium; synergism

PROJECT SUMMARY This is an application for partial support of the 2022 FASEB-sponsored Science Research Conference “Nuclear Bodies: Hubs of Genome Activity”, the first meeting solely devoted to this topic. A key objective is to provide a platform for presentation of cutting-edge, interdisciplinary discoveries, connecting nuclear bodies to cancer biology and eukaryotic genomics. Another major objective is to provide abundant opportunities for postdoc and graduate student trainees, especially women and members of groups underrepresented in science, to present their research and to engage in career development and mentoring opportunities. Nuclear bodies are essential for cellular growth and proliferation, and are involved in genome organization and regulation of gene expression. Notably, study of these bodies has included the development of broadly useful genomic tools. Dysregulation of nuclear body structure and function is strongly associated with developmental abnormalities, diseases, and cancer, which are profound global health concerns. Interest in the mechanism of nuclear body formation and in their roles in normal and disease states have intensified over the past decade. Thus, the topic of our conference is both timely and highly relevant. The conference will provide a unique platform that brings together interdisciplinary expertise, fostering synergistic and cooperative investigations of nuclear bodies. We will also promote mentorship of trainees and junior investigators, and provide networking/collaboration opportunities for all participants. There will be two poster sessions and two special initiatives for stimulating interactions with junior scientists, including a Career Mentoring session and a “Speed Networking” opportunity for junior scientists to individually interact with established faculty. The three co-organizers are Dr. Paul Kaufman (Professor, University of Massachusetts Medical School), Dr. Sui Huang (Associate Professor, Northwestern University School of Medicine), and Dr. Thoru Pederson (Professor, University of Massachusetts Medical School). They are deeply committed to diversity and promotion of broad participation of women scientists, researchers from under-represented individuals (UIs), international attendees and persons with disabilities. We have confirmed oral presentations from 36 renowned scientists, of whom 17 are women, 4 are UI investigators, and 13 are international colleagues. In selecting abstracts for oral presentations, priority will be given to new investigators (especially women and UIs). Indeed, 100% funds from this grant will be allocated for supporting participation of women, junior and UI colleagues: travel awards for 25 chosen abstracts by junior investigators, child care grants, plus funds requested for participants in these groups with especially high travel costs or other special needs. Individuals with disabilities will have complete access to all aspects of the meeting program, and child-care services will be available.

项目摘要 这是对2022 Faseb赞助的科学研究会议的部分支持的申请。 身体：基因组活动的枢纽”，第一次专门致力于该主题的会议。一个关键目标是提供一个 介绍尖端，跨学科发现的平台，将核体连接起来取消 生物学和真核基因组学。另一个主要目标是为博士后和 研究生学员，尤其是妇女和科学人数不足的团体成员 他们的研究并从事职业发展和心理机会。 核体对于细胞生长和增殖至关重要，并且参与了基因组组织和 基因表达的调节。值得注意的是，对这些机构的研究包括开发广泛有用的 基因组工具。核体结构和功能的失调与发育密切相关 异常，疾病和癌症，这是全球健康问题。对机制的兴趣 在过去的十年中，核体的形成及其在正常状态和疾病状态中的作用受到了启发。 这是我们会议的主题既及时又高度相关。 会议将提供一个独特的平台，该平台将跨学科的专业知识融合在一起，促进协同作用 和对核体的合作调查。我们还将促进学员和初中的心态 调查人员，并为所有参与者提供网络/协作机会。将有两个海报 会议和两项刺激与初级科学家互动的特殊举措，包括职业指导 会议和初级科学家的“速度网络”机会与已建立的教师单独互动。 这三个共同组织者是保罗·考夫曼（Paul Kaufman）博士（马萨诸塞大学医学院教授），Sui博士 黄（西北大学医学院副教授）和Thoru Pederson博士（教授， 马萨诸塞大学医学院）。他们深切致力于多样性和促进广泛的促进 女科学家，代表性不足的个人（UI）的研究人员，国际参与者的参与 和残疾人。我们已经确认了来自36位著名科学家的口头演讲，其中17位 是女性，4名是UI调查人员，13位是国际同事。在选择口头摘要时 演讲，将优先给新的调查人员（尤其是妇女和UI）。确实，100％的资金来自 该赠款将分配给妇女，初中和UI同事的参与：旅行奖 对于初级调查人员选择的25个摘要，托儿赠款，以及要求参与者的资金 小组的旅行成本特别高或其他特殊需求。残疾人将完成 可以访问会议计划的所有方面，并提供儿童保育服务。

项目成果

The nuclear bodies conference: Hubs of genomic activity, June 24-28, Western Shore, Nova Scotia, Canada.

核体会议：基因组活动中心，6 月 24 日至 28 日，加拿大新斯科舍省西海岸。

• DOI: 10.1096/fj.202201455r
• 发表时间: 2022
• 期刊: FASEB journal : official publication of the Federation of American Societies for Experimental Biology
• 作者: Kaufman,PaulD;Huang,Sui;Pederson,Thoru
• 通讯作者: Pederson,Thoru