Developmental Research Program (DRP)

发展研究计划（DRP）

• 批准号: 10460219
• 负责人: Jeffrey Mark Rosen
• 金额: $ 7.32万
• 依托单位: BAYLOR COLLEGE OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-19 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10460219
• 关键词: Advocate; Applications Grants; Award; Biology; Breast; Breast Cancer Patient; Collaborations; Complement; Data; Development; Funding; Individual; Medicine; Pilot Projects; Prevention; Productivity; Publications; Research; Research Personnel; Research Project Grants; Resources; Techniques; Translating; Translational Research; anticancer research; base; college; fighting; flexibility; high risk; malignant breast neoplasm; member; outreach; programs; skills; translational cancer research; translational goal

ABSTRACT To enable SPORE investigators to rapidly develop new research opportunities which could translate into early benefits for breast cancer patients, and to allow for exploration of new techniques which may require substantial efforts but which are nevertheless not ready for full scale multi-year research funding, we have devoted considerable effort and resources to this SPORE Developmental Research Program. The Executive Committee, together with the advocate members and the Internal Advisory Board, selects proposals for funding as Developmental Projects, based on their scientific merit and relevance to SPORE translational goals. Through the funding of pilot projects, we broaden the scope of research, and allow exploration of high-risk ideas that have the potential for high yields in treatment, prevention, or basic biology of breast cancer. We also attract new investigators with a wide variety of special expertise to apply their expertise to problems and questions in breast cancer research, and we catalyze productive collaborations in which individual skills and approaches combine to create progress that no single investigator could achieve alone. It is important to point out that, although only $50,000 per year is requested from SPORE funds for this program, and Baylor College of Medicine is contributing an additional $50,000 per year in recognition of the value of this outreach effort to cancer research at Baylor. During the 26 years of funding since our first Breast SPORE award in 1992, we funded 106 developmental projects, contributing to 128 publications and providing essential preliminary data for 85 successful grant applications with several still pending. Two of the new full projects in this application derived in part from developmental projects to Drs. Chang and Westbrook. This mechanism complements the larger and longer- term regular research projects, offering a degree of flexibility which leads to enhanced productivity for the SPORE as a whole.

抽象的 使孢子调查人员能够快速发展新的研究机会，以转化为 乳腺癌患者的早期益处，并允许探索可能需要的新技术 巨大的努力，但尚未准备好全面进行多年研究资金，我们已经 为这个孢子发育研究计划付出了巨大的努力和资源。高管 委员会与倡导者成员和内部顾问委员会一起选择资金的建议 作为发展项目，基于其科学优点和与孢子翻译目标的相关性。 通过试点项目的资助，我们扩大了研究范围，并允许探索高风险 在治疗，预防或乳腺癌基本生物学方面具有高收益率的想法。我们也是 吸引具有各种特殊专业知识的新调查人员将其专业知识应用于问题和 乳腺癌研究中的问题，我们促进了个人技能和个人技能的富有成效合作 方法结合起来，创造了没有一个调查员可以单独实现的进展。指向很重要 出心，尽管该计划的孢子资金每年只要求50,000美元，而贝勒学院 医学的每年额外贡献50,000美元，以表彰这种外展工作的价值 贝勒的癌症研究。 自1992年首次乳腺孢子奖以来，在26年的资金中，我们资助了106个发展 项目，为128个出版物做出贡献，并为85个成功的赠款提供基本的初步数据 仍有几个仍在待处理的申请。该应用程序中的两个新的完整项目部分来自 向博士的发展项目。 Chang和Westbrook。这种机制补充了较大和更长的 定期研究项目，提供一定程度的灵活性，从而提高了孢子的生产率 整体。