The University of Kansas Cancer Center's- MCA Rural NCORP

堪萨斯大学癌症中心 - MCA Rural NCORP

基本信息

批准号：
10460177
负责人：
GARY C. DOOLITTLE
金额：
$ 169.61万
依托单位：
UNIVERSITY OF KANSAS MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-08-13 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10460177
关键词：
Address Affect Age Area Cancer Center Cancer Control Cancer Control Research Caring Clinical Research Clinical Trials Communities Community Clinical Oncology Program Diagnosis Disadvantaged Face Funding Geography Goals Health Health Personnel Healthcare Home Hospitals Human Infrastructure Insurance Coverage Kansas Lead Leadership Localized Malignant Neoplasm Location Low income Malignant Neoplasms Midwestern United States Minority Missouri Oncology Patients Population Population Group Positioning Attribute Prevention Prevention Research Primary Health Care Process Provider Race Recording of previous events Research Research Personnel Risk Risk Factors Running Rural Rural Community Rural Population Site Southwest Oncology Group Structure Subgroup Telemedicine Time Training Universities base cancer care cancer health disparity cancer prevention care delivery care providers data quality experience geographic barrier health equity high standard human subject low socioeconomic status medical specialties member outreach patient-level barriers practice-based research network primary care setting programs rural area rural dwellers rural healthcare rural patients rural setting suburb underserved community underserved minority urban area weight loss intervention

项目摘要

Abstract The overarching goal for The University of Kansas Cancer Center – Midwest Cancer Alliance Rural NCORP (KUCC-MCA Rural NCORP) is to enhance capacity for increasing clinical trials accrual and participation of rural populations in cancer control, prevention, treatment, and care delivery clinical trials, as well as in other human research developed and conducted by NCORP Research Bases. While cancer affects all population groups, certain subgroups, including those living in rural communities, are more at risk than others.[1, 2] Contributing risk factors include older age, inadequate insurance coverage, lower socio-economic status, minority race, and more isolated geography—all of which can be barriers to receiving specialty healthcare. Inaccessibility of clinical trials due to geographical barriers clearly disadvantages rural patients and is their most frequently cited reason for not enrolling in studies.[5] Patients living in suburban areas have the highest accrual rates to clinical trials, while those by patients living in rural areas is quite low[6, 7]. The University of Kansas Cancer Center (KUCC) is strongly positioned to enhance clinical trial accrual and participation of rural populations through its leadership of the Midwest Cancer Alliance (MCA) and its cadre of accomplished investigators with extensive experience working with rural communities and practices. As the outreach network of the KUCC, the MCA has partnered with hospitals, cancer centers, and health care providers across the state of Kansas for over a decade. The goal of these MCA partnerships has always been to extend the reach of clinical research into under-represented communities, with a focus on rural and low-income communities. MCA recently expanded to include our state-wide rural primary care practice based research network, Kansas Patients and Providers Engaged in Prevention Research (KPPEPR), a network of over 75 primary care providers from across Kansas with a longstanding history of supporting cancer prevention and control research initiatives. KUCC-MCA Rural NCORP will leverage our over 45-year experience as a SWOG-member, 20-year experience providing oncology care via telemedicine, 15-year history of successfully conducting research in rural primary care settings, and 10-year experience opening and running clinical trials within rural health care networks—all supported by KUCC expertise in partnering with rural oncology and primary care practices to accomplish our goals. Specifically for the KUCC-MCA Rural NCORP, we will assess institutional, provider, clinical trial, and patient barriers to trial accrual, and implement processes to: 1) Enhance the infrastructure of local cancer centers and primary care offices to support clinical trials accrual in rural communities; 2) Expand access to clinical trials across the MCA network by offering available NCORP clinical trials in local rural communities; 3) Decrease barriers to clinical trial participation for rural and low-income patients across Kansas and western Missouri by providing trial participation opportunities in their home communities; and 4) Leverage KUCC/MCA expertise for addressing rural cancer disparities to clinical trial participation with NCORP grantees.

抽象的堪萨斯大学癌症中心 - 中西部癌症联盟农村的总体目标 NCORP (KUCC-MCA Rural NCORP) 旨在增强增加临床试验应计和农村人口参与癌症控制、预防、治疗和护理提供临床试验，以及 NCORP 研究基地开发和进行的其他人类研究，而癌症也会影响。所有人口群体、某些亚群体，包括生活在农村社区的人口，都比其他群体面临更大的风险 [1, 2] 造成风险的因素包括年龄较大、保险覆盖范围不足、社会经济地位较低地位、少数族裔和更偏僻的地理位置——所有这些都可能成为接受专业的障碍由于地理障碍而无法进行临床试验显然对农村患者和医疗保健不利。是他们最常提到的不参加研究的原因。[5] 临床试验的应计率最高，而居住在农村地区的患者的应计率相当低[6, 7]。堪萨斯癌症中心 (KUCC) 致力于提高临床试验的积累和参与度通过中西部癌症联盟 (MCA) 的领导及其取得的成就，为农村人口提供帮助具有与农村社区和实践合作的丰富经验的调查员作为外展网络。作为 KUCC 的成员，MCA 与全州的医院、癌症中心和医疗保健提供者合作这些 MCA 合作伙伴关系的目标始终是扩大堪萨斯州的影响范围。对代表性不足的社区进行临床研究，重点是农村和低收入社区。最近扩大到包括我们基于堪萨斯州农村初级保健实践的研究网络参与预防研究的患者和提供者 (KPPEPR)，一个由超过 75 个初级保健机构组成的网络来自堪萨斯州各地的提供者，在支持癌症预防和控制研究方面拥有悠久的历史 KUCC-MCA Rural NCORP 将利用我们作为 SWOG 成员超过 45 年的经验（20 年）。通过远程医疗提供肿瘤护理的经验，在以下领域成功开展研究的 15 年历史农村初级保健机构，以及在农村卫生保健领域开展和运行临床试验的 10 年经验网络——所有这些都得到 KUCC 与农村肿瘤学和初级保健实践合作的专业知识的支持，特别是对于 KUCC-MCA Rural NCORP，我们将评估机构、提供者、临床试验以及患者获得试验的障碍，并实施以下流程： 1) 增强临床试验的基础设施当地癌症中心和初级保健办公室支持农村社区的临床试验 2) 扩大通过在当地农村提供可用的 NCORP 临床试验，访问整个 MCA 网络的临床试验 3) 减少堪萨斯州农村和低收入患者参与临床试验的障碍和密苏里州西部，在他们的家乡社区提供试验参与机会；以及 4) 影响力； KUCC/MCA 的专业知识用于解决农村癌症差异与 NCORP 受助者参与临床试验的问题。