Administrative Core

行政核心

• 批准号: 10460074
• 负责人: Thomas Hope
• 金额: $ 4.55万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-15 至 2027-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10460074
• 关键词: AIDS/HIV problem; Accounting; Address; Agreement; Amendment; Area; Budgets; Cellular biology; Communication; Communities; Contracts; Cost Analysis; Data; Data Analyses; Disputes; Doctor of Philosophy; Ensure; Goals; Grant; HIV; Immunology; Individual; Infrastructure; Institution; Journals; Knowledge; Legal; Maintenance; Mediation; Monitor; Mucous Membrane; Organizational Policy; Patient Recruitments; Peer Review; Policies; Preparation; Procedures; Publications; Reporting; Research; Research Activity; Research Personnel; Resolution; Resources; Role; Schedule; Summary Reports; Supervision; Talents; Time; TimeLine; United States National Institutes of Health; Update; Viral reservoir; base; data exchange; data sharing; equipment acquisition; innovation; mast cell; meetings; multidisciplinary; nonhuman primate; organizational structure; program dissemination; programs; success; synergism; tool

PROJECT SUMMARY/ABSTRACT Thomas J. Hope, PhD, Program Director has assembled the investigative team for this proposed PPG based on the talents and expertise of each project/core leader and co-investigator. This team is perfectly posed to address the overall aim of the program to “unravel the mechanisms of HIV persistence and rebound” by focusing on leveraging innovative technical advances as well as the latest data and findings by the team and outside collaborators. The Core main focus will be to stimulate scientific synergism and the discovery of new knowledge. The Administrative Core (Core A) will serve a critical function as a centralized resource to the Program, providing for the overall management, coordination, and supervision of the Program, while facilitating the interactions between the 3 Projects and the NHP Core (Core B), to guarantee this integrated Program’s success in achieving its objective. The Administrative Core will be located at NU and will be operated under the direct guidance of Dr. Hope as Program Director (PD). The administrative core will provide the essential, functionally-interactive infrastructure supporting all projects and scientific cores with program management including frequent and timely communication platforms, resource and data exchange, timeline and fiscal oversight, critical review of research progress, and engagement with the broader HIV/AIDS research community to ensure the success of the PPG scientific goals. By facilitating efficient and frequent communications as well as iterative interactions between all investigators, both junior and senior, the AC will catalyze PPG progress by enabling PIs to proactively incorporate the advances and avoid the unplanned hurdles discovered by their colleagues in this highly interactive set of 3 projects

项目摘要/摘要 计划主任托马斯·J·霍普（Thomas J. Hope） 每个项目/核心领导者和共同投资者的才能和专家。这个团队的位置非常适合解决 该计划的总体目的是“揭示HIV持久性和反弹的机制” 利用创新的技术进步以及团队和外部的最新数据和发现 合作者。核心主要重点是刺激科学协同作用和新知识的发现。 行政核心（核心A）将作为该计划的集中资源来起关键功能， 为该计划提供整体管理，协调和监督，同时促进 3个项目与NHP核心（核心B）之间的交互，以确保该集成程序的 成功实现其目标。行政核心将位于NU，并将在 Hope博士担任计划主任（PD）的直接指导。 行政核心将提供支持所有项目的基本，功能相互互动的基础架构 以及具有计划管理的科学核心，包括经常，及时的沟通平台，资源 以及数据交流，时间表和财政监督，研究进度的批判性审查以及与 更广泛的艾滋病毒/艾滋病研究界，以确保PPG科学目标的成功。通过促进效率 并经常进行通信以及所有研究人员（大三和高级调查员）之间的迭代互动， AC将通过使PI主动地纳入进步并避免避免PPG来促进PPG的进展 他们的同事在这3个高度互动的3个项目中发现的计划外障碍