Biomaterials Engineering and Testing core (BET)

生物材料工程与测试核心（BET）

基本信息

批准号：
10457962
负责人：
ROBERT A LATOUR
金额：
$ 34.76万
依托单位：
CLEMSON UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2024-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10457962
关键词：
Address Awareness Behavior Biocompatible Materials Biological Biomedical Engineering Bioreactors Centers of Research Excellence Chemicals Collaborations Complement Core Facility Data Analyses Development Device Designs Devices Disease Drug Delivery Systems Educational workshop Effectiveness Engineering Extracellular Matrix Faculty Fee Schedules Funding Goals Graduate Education Grant Image In Vitro Institutes Instruction Journals Laboratories Materials Testing Mechanics Medical Mentors Methods Natural regeneration Outcome Performance Phase Physiological Pilot Projects Postdoctoral Fellow Property Public Health Publications Regenerative Medicine Research Research Personnel Research Project Grants Research Support Schedule Scientist Series Services Signaling Molecule Students Supervision System Systems Development Testing Tissue Engineering Tissues Training Training Activity Translational Research United States National Institutes of Health Universities biofabrication biomechanical test design human disease improved in vivo in vivo evaluation laboratory development programs repaired replacement tissue response software systems success sustainable resource systems research undergraduate education undergraduate research experience voucher working group

项目摘要

The Phase III Biomaterials Engineering and Testing (BET) Core will support the synthesis and characterization of biomaterials and the design of biomaterial systems for research projects focused on the development of translational regenerative medicine applications for the treatment of human disease. The BET Core will provide both the facilities and staff necessary to provide this research support as well as training and mentoring for facilities users. The BET Core will build upon its track record of providing this type of support over the past 9 years under the Phase I & II COBRE grants and will substantial enhance its facilities for bioreactor system design, development, and biofabrication in order to support the extended in vivo research services to be offered by the Translational Research Imaging (TRI) Core. Over the past Phase I and II COBRE programs, the BET core has provided the facilities and support contributing to the publication of over 300 referred journal publications as well as the success of several of our junior investigators for attaining their own independent NIH R01 funding. Under the Phase III program, it is our objective to develop the BET Core into a sustainable resource to provide facilities for the continued support of translational regenerative medicine research well beyond the Phase III grant period.

III期生物材料工程和测试（BET）核心将支持合成和表征生物材料和研究项目的生物材料系统的设计，重点是发展翻译再生医学用于治疗人类疾病的应用。 BET核心将提供提供此研究支持以及培训和指导的设施和人员设施用户。 BET核心将基于其过去9次提供此类支持的记录在I阶段和II阶段的多年中，将大大改善其生物反应器系统设计的设施，开发和生物制造，以支持将提供的扩展体内研究服务翻译研究成像（TRI）核心。在过去的第一阶段和第二阶段的鞋垫计划中，BET Core具有提供了有助于出版300多个推荐期刊出版物的设施和支持作为我们几名初级调查人员获得自己独立的NIH R01资金的成功。在下面第三阶段计划，我们的目标是将BET核心发展为可持续资源以提供设施为了持续支持转化的再生医学研究，远远超出了第三阶段赠款期。