Developing a sleep health intervention for shift workers

为轮班工人制定睡眠健康干预措施

基本信息

批准号：
10449909
负责人：
Jessica R Dietch
金额：
$ 20万
依托单位：
OREGON STATE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-07-01 至 2027-06-30
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10449909
关键词：
Accidents Address Area Automobile Driving Biology Care given by nurses Cessation of life Circadian Dysregulation Circadian Rhythms Clinical Clinical Investigator Clinical Trials Design Cognitive Therapy Complement Conduct Clinical Trials Confidence Intervals Data Development Development Plans Discipline of Nursing Disease Drowsiness Enrollment Fatigue Feedback Food Services Future Grant Health Heart Diseases Hematological Disease Hour Immersion Impairment Individual Institutes Intervention Light Lung diseases Malignant Neoplasms Manuals Manuscripts Medical Errors Mental Depression Mentors Mentorship Metabolic Diseases Napping National Heart, Lung, and Blood Institute Nurses Occupations Outcome Participant Pathway interactions Patients Personal Satisfaction Pilot Projects Population Preparation Public Health Randomized Randomized Controlled Trials Recommendation Reporting Research Research Design Research Project Grants Risk Risk Factors Safety Schedule Series Sleep Sleep Disorders Sleep disturbances Sleeplessness Stroke Structure Symptoms Testing Time Training Training Activity Transportation Underserved Population Visit Work acceptability and feasibility actigraphy adequate sleep barrier to care base cardiovascular disorder risk career career development circadian circadian biology compliance behavior depressive symptoms design diaries disorder risk effective intervention evidence base executive function experience feasibility research flexibility follow-up health assessment implementation facilitation implementation science improved meetings mortality multidisciplinary novel novel therapeutic intervention patient handout pilot test poor sleep power analysis prevent programs secondary outcome shift work sleep health sleep pattern telehealth therapy design trial comparing usability

项目摘要

PROJECT SUMMARY/ABSTRACT Consistent with the NHLBI Strategic Objective to “develop and optimize novel…therapeutic strategies to prevent, treat, and cure heart, lung, blood and sleep diseases,” this proposal aims to develop, refine, and preliminarily test a comprehensive, personalized, media-augmented telehealth intervention designed to improve sleep health among shift workers. Approximately 20% of the US workforce engages in some form of shift work. Shift work is common in essential occupations (e.g. nursing, transportation, food service). Shift work is associated with elevated risk for cardiovascular disease, stroke, multiple cancers, metabolic disorders, depression, driving accidents, medical errors, and all-cause mortality. One modifiable factor that contributes to increased risk for disease, accidents, errors, and death among shift workers is poor sleep health, defined as the multidimensional pattern of sleep and wake which promotes optimal health and wellbeing. Poor sleep health in shift workers manifests during both sleep (e.g., insomnia symptoms, short sleep duration) and wake (e.g., fatigue, sleepiness, executive function, depression). The proposed study seeks to improve sleep health among shift workers by developing, refining, and testing a novel intervention, termed Shift Worker Intervention for Sleep Health (SWISH), which will integrate existing effective interventions into a comprehensive program that addresses the constellation of sleep health problems experienced by many shift workers. The aims of this research are to: 1) iteratively refine and finalize the structure and materials of SWISH; 2) examine feasibility and acceptability of SWISH compared to delayed treatment control in a randomized pilot study; 3) preliminarily test the effect of SWISH on sleep health parameters; and 4) preliminarily test the effect of SWISH on wake time functioning. The proposed research plan will be the first step towards building an intervention that can contribute to the improvement and reduce the significant societal burden of poor sleep health among shift workers. This research has potential far-reaching public health implications, as the sleep health of shift workers has impacts beyond the individual (e.g., patients under a nurse's care). The candidate's planned training activities are also vital to the completion of this project. As outlined in the Career Development Plan, a multidisciplinary team of experts will provide the candidate with advanced training and mentoring in key areas including clinical trial design, conduct, and reporting, circadian rhythms biology and circadian interventions for shift work, implementation science, and development of rich, engaging media products to support therapist-led interventions. The training plan includes strong mentorship, seminars and didactics, formal coursework and institutes, hands-on training, manuscript and grant preparation, and attendance at scientific meetings. The proposed research project leverages the candidate's rigorous prior research and clinical training in sleep health assessment and interventions while providing necessary additional training to set the stage for the candidate to become an independent clinical investigator focused on increasing accessibility for sleep health interventions in underserved populations.

项目概要/摘要与 NHLBI 的战略目标一致，即“开发和优化新颖的……治疗策略，以预防、治疗和治愈心、肺、血液和睡眠疾病”，该提案旨在开发、完善和初步测试旨在改善睡眠健康的全面、个性化、媒体增强的远程医疗干预措施大约 20% 的美国劳动力从事某种形式的轮班工作。常见于基本职业（例如护理、运输、餐饮服务）。心血管疾病、中风、多种癌症、代谢紊乱、抑郁、驾驶的风险增加事故、医疗事故和全因死亡率是导致风险增加的一种可改变因素。轮班工人的疾病、事故、错误和死亡是睡眠健康状况不佳的原因，被定义为多维的促进轮班工人最佳健康和福祉的睡眠和觉醒模式。在睡眠期间（例如失眠症状、睡眠时间短）和清醒期间（例如疲劳、困倦、执行功能、抑郁）。拟议的研究旨在通过以下方式改善轮班工人的睡眠健康。开发、完善和测试一种新型干预措施，称为轮班工人睡眠健康干预措施 (SWISH)，它将把现有的有效干预措施纳入一个综合方案，以解决许多轮班工人经历的一系列睡眠健康问题本研究的目的是：1) 迭代完善并最终确定 SWISH 的结构和材料 2) 检查可行性和可接受性；随机试点研究中 SWISH 与延迟治疗对照的比较；3) 初步测试效果 SWISH 对睡眠健康参数的影响；4) 初步测试 SWISH 对唤醒时间功能的影响。拟议的研究计划将是建立干预措施的第一步，该干预措施有助于这项研究改善并减少了轮班工人睡眠健康状况不佳所造成的重大社会负担。具有潜在的深远的公共卫生影响，因为轮班工人的睡眠健康的影响超出了正常范围。候选人计划的培训活动对于个人（例如，接受护士护理的患者）也至关重要。正如职业发展计划中所述，一个多学科专家团队将完成该项目。为候选人提供关键领域的高级培训和指导，包括临床试验设计、实施、和报告、昼夜节律生物学和轮班工作的昼夜节律干预、实施科学和开发丰富、引人入胜的媒体产品来支持治疗师主导的干预措施。强有力的指导、研讨会和教学、正式课程和机构、实践培训、手稿和拟议的研究项目利用了拨款准备和参加科学会议。候选人之前在睡眠健康评估和干预方面接受过严格的研究和临床培训，同时提供必要的额外培训，为候选人成为独立的临床医生奠定基础研究人员的重点是提高服务不足的人群获得睡眠健康干预措施的机会。