NW University Program in Endo Diabetes and Hormone Action

西北大学远藤糖尿病和激素作用项目

• 批准号: 10437953
• 负责人: Joseph Bass
• 金额: $ 29.31万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1976
• 资助国家: 美国
• 起止时间: 1976-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10437953
• 关键词: Diabetes Mellitus; Hormones; Universities; programs

Rapid advances in scientific knowledge have resulted in unparalleled opportunities for new discoveries that could substantially improve human health and cure disease. A cadre of interdisciplinary scientists who can work at the interface between pathophysiology and clinical medicine is essential to accomplish this goal. It is the overarching objective of the Northwestern University Program in Endocrinology, Diabetes and Hormone Action (NUPEDHA) to enable such research in endocrinology, diabetes and metabolism. This objective will be accomplished by training basic and clinical scientists in an environment that integrates rigorous fundamental science into a disease-oriented context. An essential component of this training program is the superb, highly collaborative training faculty of 24 outstanding mentors whose research focuses on translational science related to endocrinology, diabetes, obesity and metabolism. There are 5 tightly linked co-mentors who will provide expertise in state-of-the-art “Omics” and “Big Data” approaches. There is also 1 mentor in training to ensure that there is a pathway to develop junior faculty as mentors. The overall program objectives are to 1) provide training in the fundamental biology and integrative physiology of endocrinology, diabetes, obesity and metabolism in a disease-oriented environment; 2) integrate innovative “Omics” and “Big Data” approaches into trainee research projects through co-mentorships; 3) mentor the next generation of investigators who can work at the interface between the laboratory and clinical medicine to ensure that scientific advances are rapidly translated to improve the care of patients with endocrine and metabolic disorders, including diabetes and obesity. The combined training of graduate students (two per year; up to three year appointments), PhD,or MD postdoctoral fellows (three per year; up to two year appointments) in Endocrinology and Metabolism emphasizes these objectives as well as the continuum between fundamental science and patient care. The training program contains a core of didactic activities with additional didactic experiences tailored to the needs of each trainee. Mentor training occurs at the level of graduate students, post-docs, and faculty. The Individual Development Plan (IDP) was implemented for all trainees in 2010, well before it was an NIH requirement. Professional development opportunities include training in manuscript and grant writing, presentation skills, rigor and reproducibility, responsible conduct of research, and pathways to academic and research success. The rigorous, ongoing program evaluation will continue to be overseen by the External Advisory Committee and the Northwestern University Searle Center for Advancing Learning & Teaching. NUPEDHA has an outstanding record of accomplishment. Over the past 15 years, 23% (10/43) of NUPEDHA trainees (15 predoctoral; 28 postdoctoral) have been underrepresented minorities (URM). 86% (12/15 predoctoral; 25/28 postdoctoral) have academic or clinical appointments, research positions in industry, or are continuing in training. Currently, 50% (2/4) of trainees supported by NUPEDHA are URM.

科学知识的快速进步为新发现带来了无与伦比的机会，这些新发现可以 一支由跨学科科学家组成的骨干队伍，可以大大改善人类健康并治愈疾病。 病理生理学和临床医学之间的结合对于实现这一目标至关重要。 西北大学内分泌学、糖尿病和激素作用项目 (NUPEDHA) 的目标 实现内分泌学、糖尿病和新陈代谢方面的此类研究。 在将严格的基础科学融入到科学的环境中培训基础和临床科学家 该培训计划的一个重要组成部分是出色的、高度协作的。 培养 24 名杰出导师，他们的研究重点是与以下领域相关的转化科学 内分泌学、糖尿病、肥胖症和新陈代谢方面有 5 名密切相关的共同导师。 拥有最先进的“组学”和“大数据”方法的专业知识还有 1 名培训导师，以确保： 有一条培养初级教师作为导师的途径 总体计划目标是 1) 提供培训。 内分泌学、糖尿病、肥胖和新陈代谢的基础生物学和综合生理学 2）将创新的“组学”和“大数据”方法融入实习生研究中 通过共同指导项目；3）指导能够在界面上工作的下一代研究人员 实验室和临床医学之间的联系，以确保科学进步能够迅速转化为改进 内分泌和代谢紊乱患者的护理，包括糖尿病和肥胖症。 研究生（每年两名；最多三年的任命）、博士或医学博士后研究员的培训 （每年三个；最多两年的任命）《内分泌学和新陈代谢》强调了这些目标： 以及基础科学和患者护理之间的连续体，培训计划包含以下核心内容。 教学活动，并根据每位学员的需求量身定制额外的教学经验。 个人发展计划（IDP）发生在研究生、博士后和教师层面。 早在 NIH 提出职业发展要求之前，该计划于 2010 年对所有学员实施。 机会包括手稿和拨款写作、演示技巧、严谨性和可重复性方面的培训， 负责任的研究行为以及学术和研究成功的途径。 项目评估将继续由外部咨询委员会和西北大学监督 塞尔大学 NUPEDHA 学习与教学中心拥有杰出的记录。 在过去 15 年中，23% (10/43) 的 NUPEDHA 学员（15 名博士前；28 名博士后） 代表性不足的少数群体 (URM) 86%（12/15 博士前；25/28 博士后）拥有学术或学位。 目前，50% (2/4) 的学员已在临床任命、行业研究职位或继续接受培训。 NUPEDHA 支持的是 URM。