Methods Core

方法核心

基本信息

批准号：
10436045
负责人：
Guy Brock
金额：
$ 128.66万
依托单位：
RESEARCH INST NATIONWIDE CHILDREN'S HOSP
依托单位国家：
美国
项目类别：
财政年份：
2022
资助国家：
美国
起止时间：
2022-08-01 至 2027-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10436045
关键词：
Address Applications Grants Area Artificial Intelligence Behavior Behavior Therapy Big Data Methods Capital Childhood Collaborations Communities Community Health Data Data Analyses Data Collection Data Element Development Elements Ensure Environment Evaluation Evidence based intervention Fostering Future Generations Goals Grant Growth and Development function Health Health system Healthcare Systems Information Technology Infrastructure Institutes Intervention Leadership Mental Health Mentors Methodology Methods Modeling Monitor National Institute of Mental Health Nerve Ohio Parents Patient Representative Patients Pediatric Hospitals Pilot Projects Population Population Intervention Population Study Positioning Attribute Practical Robust Implementation and Sustainability Model Predictive Analytics Preparation Prevention Research Process Productivity Protocols documentation Public Health Qualitative Methods Quality Control Research Research Design Research Institute Research Methodology Research Personnel Research Project Grants Resources Risk Science Services Standardization Statistical Models Suicide Suicide prevention Testing Universities Work Youth acute care career clinical decision-making data harmonization data management data sharing data standards design digital health health management implementation framework implementation science implementation strategy improved innovation interdisciplinary collaboration medical specialties model design multidisciplinary novel outreach population health preventive intervention program dissemination programs public health intervention reducing suicide social health determinants social structure student training success suicide rate working group

项目摘要

ABSTRACT – METHODS CORE The ASPIRES Methods Core (MC) brings together investigators from diverse and complementary backgrounds to collectively address design, implementation, methodological, and technological challenges that impede progress toward effectively reducing the youth suicide rate. Our transdisciplinary team includes experts in study design methodology for behavioral and population interventions, predictive analytics to improve clinical decision making, development of digital health interventions, implementation science, qualitative methods, integration of multi-level data elements representative of patient and community health, and geospatial modeling of environment and social structure on population health. The MC capitalizes on substantial institutional infrastructure and intellectual capital at both The Abigail Wexner Research Institute (AWRI) at Nationwide Children’s Hospital (NCH) and The Ohio State University (OSU), and Co-Leaders Drs. Brock, McAlearney, and Lin have each led both specialized and multidisciplinary teams with broad impact spanning multiple areas of health. The MC will work with ASPIRES investigators to facilitate in a pediatric population 1) development and testing of novel and scalable interventions and research-generated resources with significant appeal for stakeholders; 2) rapid and widespread dissemination of new, effective practices; 3) continuous improvement of suicide prevention interventions delivered in real-world settings; 4) interdisciplinary team science to facilitate novel and convergent solutions to intractable suicide prevention challenges; and 5) training of students, fellows, early career, and advanced investigators from diverse backgrounds to increase the diversity of investigators conducting cutting-edge translational suicide prevention research. Our MC provides a methodological anchor connecting all ASPIRES projects, and our transdisciplinary team with substantial expertise, resources, and infrastructure at both NCH and OSU will ensure that all ASPIRES projects are conducted with scientific rigor and broadly disseminated. Creative partnerships with the Zero Suicide Institute and the OSU CCTS Pilot Project Program augment outreach, engagement, and dissemination. Methodological and technological advances from our MC provide innovative approaches to overcoming challenges facing behavioral interventions for reducing the youth suicide rate. Synergistic study design elements across ASPIRES projects provide unique opportunities to study implementation and efficacy aspects of suicide prevention interventions across primary, specialty, and acute care. Collectively, these developments support innovative and rigorous evaluation of ASPIRES interventions and provide the groundwork for further design and refinement of implementation strategies necessary to scale these interventions in future studies.

摘要 - 方法核心质量方法核心（MC）汇集了来自潜水员和完整背景的研究者共同解决阻碍的设计，实施，方法论和技术挑战朝着有效降低青年自杀率的进展。我们的跨学科团队包括研究设计方法的行为和人口干预措施，预测分析以改善临床决策，数字健康干预措施的发展，实施科学，定性方法，代表患者和社区健康以及地理空间的多层次数据元素的整合对人口健康的环境和社会结构的建模。 MC大大实现 Abigail Wexner研究所（AWRI）的机构基础设施和智力资本全国儿童医院（NCH）和俄亥俄州立大学（OSU）和联合领导者Drs。布罗克， McAlearney和Lin各自领导了具有广泛影响力的专业和多学科团队多个健康领域。 MC将与志向调查人员合作，以促进儿科人群1）具有重大的新颖和可扩展干预措施以及研究生成的资源的开发和测试呼吁利益相关者； 2）快速而广泛地传播新的有效实践； 3）继续改善在现实世界中提供的预防自杀干预措施； 4）跨学科团队科学促进新颖和收敛的解决方案，以解决顽固的自杀预防挑战； 5）培训来自潜水员背景的学生，研究员，早期职业和高级调查员进行尖端翻译自杀预防研究的研究人员的多样性。我们的MC提供了方法论锚将所有志向项目连接起来，我们的跨学科团队与大量 NCH和OSU的专业知识，资源和基础设施都将确保所有志向项目都是以科学的严格性和广泛的传播进行。与零自杀研究所的创造性伙伴关系以及OSU CCTS试点项目计划扩大外展，参与和传播。方法论我们MC的技术进步提供了克服挑战的创新方法降低青年自杀率的行为干预措施。协同研究设计元素志向项目提供了研究实施和自杀有效方面的独特机会预防干预措施跨主要，专业和急性护理。这些发展共同支持对志向干预措施的创新和严格评估，并为进一步设计提供基础以及在未来的研究中规模规模所必需的实施策略的完善。