Engineering a diagnostic platform for rapid breath-based respiratory pathogen identification and treatment monitoring

设计一个诊断平台，用于基于呼吸的呼吸道病原体快速识别和治疗监测

• 批准号: 10430287
• 负责人: LESLIE CHAN
• 金额: $ 24.9万
• 依托单位: GEORGIA INSTITUTE OF TECHNOLOGY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10430287
• 关键词: Acute respiratory infection; Aftercare; Amides; Amines; Animals; Antibiotic Therapy; Antibiotics; Antimicrobial susceptibility; Bacteria; Bacterial Pneumonia; Bar Codes; Biological Assay; Blinded; Blood; Classification; Clinical; Data; Detection; Diagnosis; Diagnostic; Diagnostic tests; Disease; Drug resistance; Early Diagnosis; Engineering; Enzymes; Fingerprint; Fluorocarbons; Goals; Immune response; In Vitro; Infection; Inhalation; Leukocyte Elastase; Ligands; Lung; Mass Spectrum Analysis; Measures; Mentors; Methods; Monitor; Mus; Peptide Hydrolases; Peptides; Pharmaceutical Preparations; Phase; Predisposition; Prognosis; Pseudomonas aeruginosa; Randomized; Reporter; Research Personnel; Resistance; Sensitivity and Specificity; Signal Transduction; Specificity; Sputum; Survival Rate; System; Testing; Time; Tissues; Validation; Work; antimicrobial drug; base; classification algorithm; cohort; diagnostic platform; extracellular; in vivo; in-vivo diagnostics; mouse model; nanoparticle; nanosensors; pathogen; pathogenic bacteria; pathogenic fungus; pathogenic virus; portability; random forest; resistant strain; respiratory pathogen; response; urinary; ventilator-associated pneumonia; volatile organic compound