NYUCI-ES: Psychosocial Intervention to Improve Health Outcomes for Chinese and Korean ADRD Caregivers

NYUCI-ES：通过心理社会干预改善中国和韩国 ADRD 护理人员的健康状况

• 批准号: 10437459
• 负责人: Bei Wu
• 金额: $ 73.31万
• 依托单位: RUTGERS BIOMEDICAL/HEALTH SCIENCES-RBHS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-24 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10437459
• 关键词: Adult; Alzheimer' s disease related dementia; American; Area; Asian Americans; Asians; Belief; Biological; Biological Assay; Blood specimen; COVID-19; Cardiometabolic Disease; Caregivers; Caring; Chinese American; Chinese People; Chronic Disease; Collaborations; Conflict (Psychology); Control Groups; Counseling; Cultural Backgrounds; Cultural Diversity; Dementia caregivers; Diabetes Mellitus; Disease Management; Educational Materials; Elderly; Emotional; Enrollment; Evidence based intervention; Failure; Family; Family Caregiver; Glycosylated Hemoglobin; Health; Health Policy; Health Promotion; Hypertension; Individual; Inflammation; Intake; Intervention; Korean American; Koreans; Language; Lead; Linguistics; Mainstreaming; Mediating; Mediator of activation protein; Mental Depression; Mental Health; Metabolic; Metabolism; Minority; Minority Groups; Modeling; Morbidity - disease rate; Multilingualism; New Jersey; New York; Nursing Homes; Outcome; Oxidative Stress; Patient Self-Report; Personal Satisfaction; Persons; Physiological; Policies; Population; Psychosocial Assessment and Care; Psychosocial Factor; Public Health; Quality of life; Questionnaires; Randomized; Randomized Controlled Trials; Research; Research Project Grants; Risk; Risk Factors; Sampling; Self Management; Services; Social Work; Social isolation; Social support; Stereotyping; Stress; Structure; Support Groups; Testing; Translating; arm; biological adaptation to stress; cardiometabolic risk; caregiver interventions; caregiving; caregiving outcomes; community organizations; cultural values; dementia care; dementia caregiving; depressive symptoms; efficacy testing; evidence base; follow-up; group intervention; health equity; health literacy; improved; lipid metabolism; metropolitan; multi-component intervention; peer support; physical conditioning; provider intervention; psychological outcomes; psychosocial; service providers; social; social media; social stigma; symptomatic improvement; underserved community

Research Project 3 – NYUCI-ES – Abstract The physical and emotional demands of dementia caregiving can have enormous negative effects on caregivers’ physical and mental health. Dementia caregivers have increased risk of hypertension and diabetes, compared to non-caregivers, especially in minority populations. This study will conduct a two-arm randomized controlled trial to test the efficacy of a culturally tailored version of the NYU Caregiver Intervention (NYUCI) plus enhanced support (ES) through online chat groups (the NYUCI plus WeChat/Kakaotalk [population social media app for Chinese/Korean] peer support which we call the NYUCI-ES in reducing health risks for cardiometabolic disease among older Chinese and Korean-American adults caring for relatives with ADRD. The NYUCI has proven efficacy in reducing psychological outcomes among largely White samples of caregivers of persons with ADRD and has been widely replicated and translated in the USA and elsewhere. This study will provide the first large- scale test of the potential effects of the NYUCI-ES, a multicomponent intervention that includes individual and family counseling and ongoing support via support group and online chat groups and ad hoc (on demand) counseling. In collaboration with community organizations across the New York and northern New Jersey metropolitan area, we will enroll 300 caregivers of people with ADRD (150 Chinese and 150 Korean) in this study. Aim 1: Develop culturally adapted informational and educational materials about dementia and caregiving issues for social service providers of the intervention and for family caregivers. Aim 2: Test the hypothesis, H1: A counseling and support intervention (the NYUCI-ES) will significantly improve psychosocial factors such as depression, stress self-rated health and chronic disease management among Chinese and Korean-American ADRD caregivers and these changes will be mediated by improvement in social support. H1a: By the first (6- month) follow-up, the mediators (increases in social support, stress reaction) will improve significantly in the intervention group compared to baseline values and the control group. H1b: These improvements will be maintained, and lead to reduction in depressive symptoms, and improvement in self-reported health and chronic disease self-management by the 12-month follow-up compared to the control group. Aim 3: Test the hypothesis, H2: the NYUCI-ES will reduce biologic risk factors, including metabolic health (glycosylated hemoglobin) and inflammation (Oxidative stress, lipid metabolism, etc.) within 6 months of enrollment compared to baseline and a control group; these changes will be mediated through increases in social support and decreases in depressive symptoms and will be maintained at the 12-month follow-up. The public health significance of these findings will likely have an impact on health care policy for CGs from diverse underserved ethnic and cultural backgrounds, potentially reducing morbidity, and improving their quality of life.

研究项目3 - Nyuci-ES - 摘要 痴呆症护理的身体和情感需求可能会对护理人员产生巨大的负面影响 身心健康。痴呆症护理人员增加了高血压和糖尿病的风险 给非照顾者，尤其是在少数民族中。这项研究将进行两臂随机控制 试验以测试纽约大学护理人员干预（NYUCI）和增强的文化量身定制版本的有效性 通过在线聊天组（ES）支持（ES）（Nyuci Plus Wechat/Kakaotalk [人口社交媒体应用程序 中文/韩语]同伴支持，我们称之为降低心脏代谢疾病健康风险的NyuciE 在携带ADRD亲戚的老年中国和韩裔美国人中。 Nyuci已证明 在降低ADRD的人的护理人员样本中，降低心理成果的功效 并在美国和其他地方被广泛复制和翻译。这项研究将提供第一个大型 对NyuciE的潜在影响的比例测试，Nyuci-Es是一种多组分干预措施，包括个人和 通过支持小组和在线聊天小组以及临时支持（按需）的家庭咨询和持续支持（按需） 咨询。 与纽约和新泽西州北部的社区组织合作 我们将在此注册300名ADRD（150个中文和150韩语）的护理人员 学习。目标1：开发有关痴呆和照料的文化适应性和教育材料 社会服务提供者的干预和家庭护理人员的问题。目标2：检验假设，H1： 咨询和支持干预（Nyuci-es）将显着改善社会心理因素，例如 中国和韩裔美国人的抑郁症，压力自我评估的健康和慢性病管理 ADRD护理人员和这些变化将通过改善社会支持来介导。 H1a：第一个（6- 一个月的随访，调解人（社会支持的增加，压力反应）将在 与基线值和对照组相比，干预组。 H1B：这些改进将是 维持并导致抑郁症状减轻，并改善自我报告的健康和慢性 与对照组相比，疾病自我管理为12个月的随访。目标3：检验假设， H2：NyuciE将减少生物学危险因素，包括代谢健康（糖基化血红蛋白）和 与基线相比，在入学后6个月内炎症（氧化应激，脂质代谢等） 对照组；这些变化将通过增加社会支持并减少抑郁症来介导 症状将在12个月的随访中保持。 这些发现的公共卫生意义可能会对CGS的医疗保健政策产生影响 来自潜水员服务不足的种族和文化背景，可能降低发病率并改善其 生活质量。