Biostatistics/Bioinformatics Core

生物统计学/生物信息学核心

基本信息

批准号：
10428583
负责人：
Yongzhao Shao
金额：
$ 25.25万
依托单位：
NEW YORK UNIVERSITY SCHOOL OF MEDICINE
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-06-01 至 2025-05-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10428583
关键词：
Adoption Algorithmic Analysis Alzheimer&apos s Disease American Animals Behavioral Bioinformatics Biological Markers Biometry Collaborations Communities Consultations Data Data Analyses Data Collection Data Set Databases Doctor of Philosophy Electrons Ensure Funding Genes Genomics Human In Vitro Informatics Investigation Knowledge Portal Laboratories Laboratory Study Leadership Masks Mass Fragmentography Mass Spectrum Analysis Measurement Messenger RNA Metadata MicroRNAs Mission Multiomic Data Mus Online Systems Ontology Outcomes Research Pathogenesis Pathway Analysis Proteins Proteomics Publications Publishing Randomized Records Reporting Reproducibility Research Research Design Research Personnel Research Project Grants Resources Sampling Services Source Statistical Data Interpretation Statistical Models System Time Transgenic Animals Visualization Visualization software animal data base bioinformatics pipeline clinically relevant computer framework computerized tools data integration data management data sharing experience human tissue in vivo innovation insight ionization large scale data mass spectrometer medical schools metabolomics multiple omics novel novel strategies professor public repository repository small molecule statistics synergism transcriptomics translational study

项目摘要

PROJECT SUMMARY The Biostatistics and Bioinformatics Core (Core D) of this P01 will provide statistical and bioinformatics collaboration and consultation to all Research Projects and Cores. Consultation is available from the study design and planning stages through implementation, data management, statistical and bioinformatics analysis, and interpretation of results. Core D will provide support for all proposed laboratory studies and translational studies, including investigation of various biomarkers based on human samples and animal studies to support the overarching mission and central scientific strategy of the P01. Furthermore, strategies for the systematic selection of samples from all the projects and the coordination of informatics support and data management in Core D will permit data sharing and overall integration of results across projects of this P01 to develop novel approaches to understanding the pathogenesis and treating AD.

项目摘要该P01的生物统计学和生物信息学核心（核心D）将提供统计和生物信息学与所有研究项目和核心的协作和咨询。可以从研究中获得咨询通过实施，数据管理，统计和生物信息学分析设计和计划阶段，和结果的解释。核心D将为所有拟议的实验室研究和翻译提供支持研究，包括基于人类样本和动物研究的各种生物标志物的研究 P01的总体任务和中央科学策略。此外，系统的策略从所有项目中选择样本以及信息学支持和数据管理的协调核心D将允许数据共享和整个P01项目的结果整体整合以开发新颖理解发病机理和治疗AD的方法。