UAB Predoctoral Training Grant in Translational and Molecular Sciences

UAB 转化和分子科学博士前培训补助金

• 批准号: 10417022
• 负责人: RAKESH P. PATEL
• 金额: $ 26.78万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-07-01 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10417022
• 关键词: Grant; Molecular; Science; Training; pre-doctoral

This is a new pre-doctoral training grant application in Translational and Molecular Sciences (TMS) at the University of Alabama at Birmingham (UAB). Currently, too few PhD graduates are entering the workforce with sufficient training in pathobiology of disease and translational experiences to effectively translate molecular advances into clinical practice. This proposal addresses this need with our goal being to provide a training environment that develops the necessary skills for the next generation of PhD biomedical scientists to incorporate translational objectives into their research and prepare them for the workforce of tomorrow. Our recent experiences in graduate education show increased demand from students for training in translational research. A major challenge in effective training in translational sciences for pre-doctoral students is the need to incorporate multiple disciplines and concepts ranging from understanding disease mechanisms, understanding of how findings may be translated in academia or industry, to understanding regulatory oversight procedures and rules. We propose a 2 year program (with 6 students per year) with students enrolling at the beginning of their second year. An integrative curriculum is proposed that involves didactic elements (that includes understanding disease mechanisms, drug discovery and development, translational research administration), career and translational research enrichment activities (including enrollment in a Certificate program in Translational and Molecular Sciences, academia and industry workshops, CTSA interactions and team based exercises that foster innovation, entrepreneurship and requisite skills and knowledge for commercializing discoveries) and meaningful clinical / patient interaction experiences, the latter of which will be linked with the trainees’ research interests. We feel that providing students with training in translational research early during a student’s matriculation will develop skills and enable them to incorporate translational thinking into their research and prepare them for the diverse requirements for the future workforce. To achieve this, we have assembled 60 training faculty with well-funded laboratories and a unique array of expertise and experience that address fundamental scientific problems with a strong emphasis on translation and human disease. Several disease areas that are perennial strengths of UAB are represented and will provide breadth for students in diverse research disciplines. This proposal underscores our previous and ongoing commitment to pre-doctoral education and our collective goal of providing an environment for students to learn and develop the skills they will require to be successful in the biomedical research and other science related occupations.

这是一项新的转化与分子科学 (TMS) 博士前培训资助申请 阿拉巴马大学伯明翰分校 (UAB) 目前，进入职场的博士毕业生太少。 足够的疾病病理学培训和转化经验，以​​有效转化分子 该提案解决了这一需求，我们的目标是提供培训。 为下一代生物医学博士科学家培养必要技能的环境 将转化目标纳入他们的研究中，并为他们成为未来的劳动力做好准备。 最近的研究生教育经验表明，学生对转化培训的需求不断增加 对博士前学生进行有效的转化科学培训的一个主要挑战是需要。 整合多个学科和概念，包括理解疾病机制、 了解如何在学术界或工业界转化研究结果，了解监管监督 我们提出一个为期 2 年的课程（每年 6 名学生），学生在该校注册。 第二学年开始时，提出了包含教学要素的综合课程。 包括了解疾病机制、药物发现和开发、转化研究 管理）、职业和转化研究丰富活动（包括注册证书 转化和分子科学、学术界和行业研讨会、CTSA 互动和 以团队为基础的练习，培养创新、创业精神和必要的技能和知识 商业化的发现）和有意义的临床/患者互动体验，后者将是 我们认为为学生提供转化研究的培训。 在学生入学初期将培养技能并使他们能够将转化思维融入到 他们的研究并为他们满足未来劳动力的多样化需求做好准备。 汇集了 60 名培训教师，他们拥有资金雄厚的实验室以及一系列独特的专业知识和经验， 解决基本科学问题，重点关注翻译和人类疾病。 作为 UAB 常年优势的疾病领域都有代表性，并将为学生提供广度 该提案强调了我们之前和当前对博士前的承诺。 教育和我们的集体目标是为学生提供学习和发展技能的环境 将需要在生物医学研究和其他科学相关职业中取得成功。