Development and Initial Efficacy Testing of a Cognitive-Behavioral Intervention to Treat Adolescent Binge Eating

治疗青少年暴食的认知行为干预措施的开发和初步疗效测试

基本信息

批准号：
10416090
负责人：
Janet A Lydecker
金额：
$ 19.49万
依托单位：
YALE UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-07-01 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10416090
关键词：
Adolescent Adolescent Development Adult Advisory Committees Advocate Anxiety Disorders Attention Award Behavior Behavior Control Behavioral Model Behavioral inhibition Binge Eating Binge eating disorder Body mass index Child Clinical Clinical Research Clinical Trials Cognitive Cognitive Science Cognitive Therapy Complement Consult Control Groups Data Decision Making Development Distress Doctor of Philosophy Eating Eating Disorders Effectiveness Emotional Evidence based treatment Feedback Feeling Focus Groups Food Foundations Frequencies Funding Future Grant Health Healthy Eating Height Impaired health Impulsivity International Intervention Lead Learning Manuals Measures Mediator of activation protein Mental Depression Mental Health Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Methodology Obesity Parents Patients Pattern Persons Pilot Projects Positioning Attribute Process Protocols documentation Psychiatry Psychology Psychotherapy Randomized Research Research Activity Research Personnel Research Training Resources Rewards Series Statistical Data Interpretation Testing Therapeutic Studies Thinking Training Training Activity Weight Youth active control adolescent patient adult obesity base career career development cognitive development effectiveness trial efficacy testing efficacy trial evidence base excessive weight gain executive function experience food consumption high risk improved individualized medicine insight interest interpersonal therapy loss of control over eating obesity in children physical conditioning pilot test professor programs psychosocial research and development secondary outcome self esteem skills social statistics therapy design therapy development treatment planning

项目摘要

PROJECT SUMMARY/ ABSTRACT Binge-eating episodes involve eating an unusually large amount of food and feeling unable to control the type or amount of food consumed while eating. Among adolescents, loss-of-control (LOC) eating is a precursor to excess weight gain and binge-eating disorder. Binge/LOC eating is also associated with physical and mental health impairments, and psychosocial distress. Although excess weight and binge/LOC eating have serious immediate and long-term consequences, assessment and treatment have received minimal attention for adolescent patients. Among adults, cognitive-behavioral therapy (CBT) has a strong evidence base for binge- eating disorder. Among adolescents, there are no well-established treatments for binge/LOC eating. Adolescents have unique social, cognitive and emotional needs because of their developmental stage; unique treatment approaches are essential to meet these unique needs. This Mentored Patient-Oriented Research Career Development Award (K23 with Clinical Trial) builds upon the candidate’s programmatic clinical- research interest in the treatment of weight and eating disorders. Training objectives and research activities for this K23 are to develop new skills and expertise in (a) treatment development and initial efficacy testing as described by the Stage Model of Behavioral Therapies Research, and (b) advanced statistical skills for repeated and dyadic data. Development of CBT for adolescent binge/LOC eating will make a significant contribution to our understanding of treatment in an important step towards reducing health impairments and psychosocial distress associated with adolescent binge/LOC eating and excess weight. Research activities are tightly integrated with training activities and mentorship from an advisory team of internationally-recognized scholars to facilitate the candidate’s development of necessary skills to become an independent and impactful investigator in the fields of childhood obesity and eating disorders. The training plan enlists the mentorship of Carlos Grilo, PhD, Professor of Psychiatry and Psychology and Director of the Yale Program for Obesity, Weight, and Eating Research, and Wendy Silverman, PhD, Alfred A. Messer Professor in the Yale Child Study Center and Professor of Psychology and Director of the Yale Child Study Center Program for Anxiety Disorders. Dr. Grilo’s expertise in the treatment of adult binge-eating disorder and obesity is complemented by Dr. Silverman’s expertise in youth treatments. Together, their mentorship will facilitate successful execution of the proposed research aims and career objectives. Research and training activities will also make use of other clinical-research educational programs at Yale (e.g., CTSA, Psychotherapy Development Center) that offer many formal training activities, opportunities, and resources. Skills (treatment development and advanced statistical analysis) will yield a new treatment and initial efficacy data for future tests of efficacy and effectiveness throughout the candidate’s career.

项目概要/摘要暴食症包括吃下异常大量的食物并感觉无法控制食物的类型在青少年中，饮食失控（LOC）是出现这种情况的先兆。体重增加过多和暴食症也与身体和精神有关。尽管体重过重和暴饮暴食会造成严重的健康损害和社会心理困扰。近期和长期的后果、评估和治疗很少受到关注在青少年患者中，认知行为疗法（CBT）对于暴饮暴食有强有力的证据基础。对于青少年的饮食失调，目前还没有针对暴饮暴食/LOC 饮食的完善治疗方法。青少年因其独特的发展阶段而具有独特的社交、认知和情感需求；治疗方法对于满足这些独特的需求至关重要。职业发展奖（K23 临床试验）以候选人的计划性临床为基础对体重和饮食失调治疗的研究兴趣培训目标和研究活动。该 K23 将在 (a) 治疗开发和初步疗效测试方面培养新技能和专业知识行为疗法研究阶段模型所描述的，以及（b）高级统计技能针对青少年暴饮暴食/LOC 饮食的重复和二元数据的开发将产生重大影响。有助于我们对治疗的理解，这是减少健康损害和与青少年暴饮暴食和超重相关的心理社会困扰。与国际公认的咨询团队的培训活动和指导紧密结合学者帮助候选人发展必要的技能，成为独立且有影响力的人儿童肥胖和饮食失调领域的研究员。该培训计划得到了精神病学和心理学教授 Carlos Grillo 博士的指导，耶鲁大学肥胖、体重和饮食研究项目主任、Wendy Silverman 博士、Alfred A. 耶鲁儿童研究中心梅塞尔教授、心理学教授兼耶鲁儿童中心主任焦虑症研究中心项目。格里洛博士在治疗成人暴食方面的专业知识。西尔弗曼博士在青少年治疗方面的专业知识对疾病和肥胖症进行了补充。研究指导将有助于成功执行拟议的研究目标和职业目标。培训活动还将利用耶鲁大学的其他临床研究教育项目（例如 CTSA、心理治疗发展中心）提供许多正式的培训活动、机会和资源。技能（治疗开发和高级统计分析）将产生新的治疗方法和初步疗效用于未来测试候选人整个职业生涯中的功效和效果的数据。