Development and Initial Efficacy Testing of a Cognitive-Behavioral Intervention to Treat Adolescent Binge Eating

治疗青少年暴食的认知行为干预措施的开发和初步疗效测试

• 批准号: 9914267
• 负责人: Janet A Lydecker
• 金额: $ 19.49万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9914267
• 关键词: Adolescent; Adolescent Development; Adult; Advisory Committees; Advocate; Anxiety Disorders; Attention; Award; Behavior; Behavior Control; Behavioral Model; Behavioral inhibition; Binge Eating; Binge eating disorder; Body mass index; Child; Clinical; Clinical Research; Clinical Trials; Cognitive; Cognitive Science; Cognitive Therapy; Complement; Consult; Control Groups; Data; Decision Making; Development; Distress; Doctor of Philosophy; Eating; Eating Disorders; Effectiveness; Emotional; Evidence based treatment; Feedback; Feeling; Focus Groups; Food; Foundations; Frequencies; Funding; Future; Grant; Health; Healthy Eating; Height; Impaired health; Impulsivity; International; Intervention; Lead; Learning; Manuals; Measures; Mediator of activation protein; Mental Depression; Mental Health; Mentored Patient-Oriented Research Career Development Award; Mentors; Mentorship; Methodology; Obesity; Parents; Patients; Pattern; Persons; Pilot Projects; Positioning Attribute; Process; Protocols documentation; Psychiatry; Psychology; Psychotherapy; Randomized; Research; Research Activity; Research Personnel; Research Training; Resources; Rewards; Series; Statistical Data Interpretation; Testing; Therapeutic Studies; Thinking; Training; Training Activity; Weight; Weight Gain; Youth; active control; adolescent patient; adult obesity; base; career; career development; cognitive development; effectiveness trial; efficacy testing; efficacy trial; evidence base; executive function; experience; food consumption; high risk; improved; individualized medicine; insight; interest; interpersonal therapy; loss of control over eating; obesity in children; physical conditioning; professor; programs; psychosocial; research and development; secondary outcome; self esteem; skills; social; statistics; therapy design; therapy development; treatment planning

PROJECT SUMMARY/ ABSTRACT Binge-eating episodes involve eating an unusually large amount of food and feeling unable to control the type or amount of food consumed while eating. Among adolescents, loss-of-control (LOC) eating is a precursor to excess weight gain and binge-eating disorder. Binge/LOC eating is also associated with physical and mental health impairments, and psychosocial distress. Although excess weight and binge/LOC eating have serious immediate and long-term consequences, assessment and treatment have received minimal attention for adolescent patients. Among adults, cognitive-behavioral therapy (CBT) has a strong evidence base for binge- eating disorder. Among adolescents, there are no well-established treatments for binge/LOC eating. Adolescents have unique social, cognitive and emotional needs because of their developmental stage; unique treatment approaches are essential to meet these unique needs. This Mentored Patient-Oriented Research Career Development Award (K23 with Clinical Trial) builds upon the candidate’s programmatic clinical- research interest in the treatment of weight and eating disorders. Training objectives and research activities for this K23 are to develop new skills and expertise in (a) treatment development and initial efficacy testing as described by the Stage Model of Behavioral Therapies Research, and (b) advanced statistical skills for repeated and dyadic data. Development of CBT for adolescent binge/LOC eating will make a significant contribution to our understanding of treatment in an important step towards reducing health impairments and psychosocial distress associated with adolescent binge/LOC eating and excess weight. Research activities are tightly integrated with training activities and mentorship from an advisory team of internationally-recognized scholars to facilitate the candidate’s development of necessary skills to become an independent and impactful investigator in the fields of childhood obesity and eating disorders. The training plan enlists the mentorship of Carlos Grilo, PhD, Professor of Psychiatry and Psychology and Director of the Yale Program for Obesity, Weight, and Eating Research, and Wendy Silverman, PhD, Alfred A. Messer Professor in the Yale Child Study Center and Professor of Psychology and Director of the Yale Child Study Center Program for Anxiety Disorders. Dr. Grilo’s expertise in the treatment of adult binge-eating disorder and obesity is complemented by Dr. Silverman’s expertise in youth treatments. Together, their mentorship will facilitate successful execution of the proposed research aims and career objectives. Research and training activities will also make use of other clinical-research educational programs at Yale (e.g., CTSA, Psychotherapy Development Center) that offer many formal training activities, opportunities, and resources. Skills (treatment development and advanced statistical analysis) will yield a new treatment and initial efficacy data for future tests of efficacy and effectiveness throughout the candidate’s career.

项目摘要/摘要 暴饮暴食的情节涉及吃异常大量的食物，并且无法控制这种类型 或进食时消耗的食物数量。在青少年中，控制丧失（LOC）饮食是 体重增加过多和暴饮暴食障碍。暴饮暴食/LOC饮食也与身体和精神 健康障碍和社会心理困扰。尽管超出了体重和暴饮暴食/饮食严重 立即和长期后果，评估和治疗对 青春期患者。在成年人中，认知行为疗法（CBT）具有强大的狂欢证据基础 饮食失调。在青少年中，没有公认的暴饮暴食治疗方法。 由于他们的发展阶段，青少年有独特的社会，认知和情感需求。独特的 治疗方法对于满足这些独特的需求至关重要。这项指导的以患者为导向的研究 职业发展奖（带临床试验的K23）建立在候选人的程序临床基础上 研究对体重和饮食失调治疗的兴趣。培训对象和研究活动 该K23旨在在（a）治疗开发和初步有效测试方面发展新技能和专业知识 由行为疗法研究的舞台模型描述，（b） 重复和二元数据。为青少年/loc饮食开发CBT将成为重要的 在减少健康障碍和 与青少年的Benge/LOC饮食相关的社会心理困扰，超过体重。研究活动是 与国际公认的咨询团队的培训活动和心态紧密融合 学者促进候选人发展必要技能，成为独立有影响力的 儿童肥胖和饮食失调领域的研究者。 该培训计划获得了Carlos Grilo，Phd，精神病学和心理学教授的指导 耶鲁大学肥胖，体重和饮食研究计划的主任以及Alfred A. Wendy Silverman博士 耶鲁儿童学习中心的梅塞尔教授，心理学教授和耶鲁儿童的主任 学习中心焦虑症计划。 Grilo博士在治疗成人Benge的专业知识 Silverman博士在青年治疗方面的专业知识完成了障碍和肥胖症。在一起，他们 Menorship将有助于成功执行拟议的研究目标和职业目标。研究 培训活动还将利用耶鲁大学的其他临床研究教育计划（例如CTSA， 心理治疗开发中心）提供许多正式的培训活动，机会和资源。 技能（治疗开发和高级统计分析）将产生新的治疗和初始效率 在整个候选人职业生涯中的未来有效性和有效性测试的数据。