Developing the first 100% real food solution for tube feeding that is prescription ready: Improving access to a healthy balanced diet for all.

开发%20the%20first%20100%%20real%20food%20solution%20for%20tube%20feeding%20that%20is%20prescription%20ready:%20改善%20access%20to%20a%20healthy%20balanced%20diet%20for%20all。

• 批准号: 10068044
• 金额: $ 35.63万
• 依托单位: WILBO'S BLENDS LIMITED
• 依托单位国家: 英国
• 项目类别: Collaborative R&D
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=10068044
• 关键词: Developing; first; 100; real; food

Over 1 million individuals in the EU and North America (\>70,000 people in the UK) require long-term tube feeding, typically using formula through a tube inserted directly into the stomach. Commercial formula is expensive, costing the NHS more than £200million/year. Formula feeding can cause various side-effects including nausea, vomiting, reflux, and constipation which impact quality of life and NHS budgets. Side-effects can result in hospitalisation and a reliance on long-term medicines to manage them.There's been huge growth in the use of home-blended food, 'blended diet', as an alternative to formula. Blended diet has fewer side effects, improving quality of life and reducing reliance on other medicines. Crucially, home-blended food is far cheaper for society to sustain, costing £10-£20 per-person per-week, versus up to £245 per-person per-week for formula, an 80% reduction in costs for the NHS.Wilbo's Blends' vision is to help everyone with a feeding tube have equitable access to real food via prescription to reduce diet-related inequalities. We project \>£30m/year savings could be realised within 5-years by reducing formula, the medicines required alongside formula and the cost of unnecessary hospitalisations \[UoM, Health Economics\].Our company is user-led 'inspired by Wilbo'. William, born with complex care needs has, like thousands of others, successfully transitioned onto blended diet, reducing symptoms. This drives our commitment to support the tube feeding population and ensure equitable access to the blended diet.We will create a set of organic, 100% real food products for people (age3+) that are tube fed which will be the first to meet Food for Special Medical Purposes (FSMP) regulations, be approved by the Advisory Committee on Borderline Substances (ACBS) and be available on prescription.???Wilbo's will overcome technical complexities associated with formulating the products, manufacturing at scale and testing with users to meet:* Nutritional profile within FSMP tolerances* Calorie density \>1.0kcal/ml* A consistency that is smooth enough to pass through a feeding tube (IDDSI-level-3).* Sterile packaging that is shelf-stable for up to 12months and can connect to a syringe.This project brings together a world-class team of academic, clinical and commercialisation professionals from across Manchester's innovation ecosystem, working closely with FSMP manufacturing specialists, dietitians and regulatory consultants.Our products are designed to support tube fed individuals, but they can also be accessed by people with an oral diet who have an unsafe swallow (called dysphagia), including stroke and cancer patients. We will work to drive access for all.

欧盟和北美有超过 100 万人（英国有超过 70,000 人）需要长期管饲，通常通过直接插入胃中的管子使用配方奶。商业配方奶价格昂贵，花费了 NHS 超过 2 亿英镑。配方奶喂养会引起各种副作用，包括恶心、呕吐、反流和便秘，这些副作用会影响生活质量和 NHS 预算。副作用可能导致住院和对长期药物的依赖。家庭混合食品（“混合饮食”）的使用大幅增长，作为配方食品的替代品，混合饮​​食的副作用较少，可以改善生活质量并减少对其他药物的依赖。混合食品对于社会的维持来说要便宜得多，每人每周花费 10-20 英镑，而配方奶每人每周高达 245 英镑，这使 NHS.Wilbo 的成本降低了 80% Blends 的愿景是帮助每个使用饲管的人通过处方公平地获得真正的食物，以减少与饮食相关的不平等。我们预计，通过减少配方奶、配方奶和配方奶所需的药物，每年可以节省 3000 万英镑。不必要的住院费用\[UoM，健康经济学\]。我们公司是用户主导的，“受到 Wilbo 的启发”，William 出生时就具有复杂的护理需求，与其他数千人一样，已成功过渡到混合型。这促使我们致力于支持管饲人群并确保公平获得混合饮食。我们将为管饲人群（3 岁以上）创造一套有机、100% 纯正的食品，这将是首先满足特殊医学用途食品 (FSMP) 法规，获得边界物质咨询委员会 (ACBS) 批准，并可凭处方使用。???Wilbo's 将克服与产品配制、大规模生产和测试相关的技术复杂性和用户需要满足：* 营养成分在 FSMP 公差范围内* 卡路里密度 \>1.0kcal/ml* 稠度足以顺利通过饲管（IDDSI 3 级）。* 无菌包装，可稳定保存长达 12 个月，可以连接到注射器。该项目汇集了来自曼彻斯特创新生态系统的世界一流学术、临床和商业化专业人士团队，与 FSMP 制造专家、营养师密切合作我们的产品旨在支持管饲人群，但吞咽不安全（称为吞咽困难）的口服饮食人群也可以使用这些产品，包括中风和癌症患者。我们将努力推动所有人使用这些产品。 。